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Select item 117023781.

Upshot of Some Bioactive Compounds on Angiogenesis in Retinal Pigment Epithelial Cells

Serkan Sen, Murat Kasikci

J Cell Mol Med. 2025 Jan; 29(1): e70327. Published online 2025 Jan 3. doi: 10.1111/jcmm.70327

PMCID:: PMC11702378

Abstract Article PDF–1000K

Select item 116977212.

Deep-learning prediction of cardiovascular outcomes from routine retinal images in individuals with type 2 diabetes

Mohammad Ghouse Syed, Emanuele Trucco, Muthu R. K. Mookiah, Chim C. Lang, Rory J. McCrimmon, Colin N. A. Palmer, Ewan R. Pearson, Alex S. F. Doney, Ify R. Mordi

Cardiovasc Diabetol. 2025; 24: 3. Published online 2025 Jan 2. doi: 10.1186/s12933-024-02564-w

PMCID:: PMC11697721

Abstract Article PDF–1.6M

Select item 116267053.

Causal association between glaucoma and risk of retinal vascular occlusion: a Mendelian randomization study

Zixun Wang, Kaihua Xu, Xiaoling Zhang, Ruihua Wei, Zhiqing Li

J Int Med Res. 2024 Dec; 52(12): 03000605241286985. Published online 2024 Dec 9. doi: 10.1177/03000605241286985

PMCID:: PMC11626705

Abstract Article PDF–765K

Select item 115735224.

VEGF inhibition increases expression of HIF-regulated angiogenic genes by the RPE limiting the response of wet AMD eyes to aflibercept

Deepti Sharma, Evan Lau, Yu Qin, Kathleen Jee, Murilo Rodrigues, Chuanyu Guo, Aumreetam Dinabandhu, Emma McIntyre, Shaima Salman, Yousang Hwang, Ala Moshiri, Gregg L. Semenza, Silvia Montaner, Akrit Sodhi

Proc Natl Acad Sci U S A. 2024 Nov 12; 121(46): e2322759121. Published online 2024 Nov 5. doi: 10.1073/pnas.2322759121

PMCID:: PMC11573522

Abstract Article PDF–8.1M

Select item 115639185.

Inflammasome activation aggravates choroidal neovascularization

Ryan D. Makin, Ivana Apicella, Roshni Dholkawala, Shinichi Fukuda, Shuichiro Hirahara, Yoshio Hirano, Younghee Kim, Ayami Nagasaka, Yosuke Nagasaka, Siddharth Narendran, Felipe Pereira, Akhil Varshney, Shao-bin Wang, Jayakrishna Ambati, Bradley D. Gelfand

Angiogenesis. 2024; 27(4): 919–929. Published online 2024 Sep 24. doi: 10.1007/s10456-024-09949-1

PMCID:: PMC11563918

Abstract Article PDF–1.8M

Select item 115255796.

Adverse effects of CXCR2 deficiency in mice reared under non-gnotobiotic conditions

Maximilian J. Garcia, Monica S. Morales, Tzushan S. Yang, Joseph Holden, Olivia L. Bossardet, Samuel A. Palmer, Marvarakumari Jhala, Stephen Priest, Neeraj Namburu, Nolan Beatty, Sariah E. D’Empaire Salomon, Jordan Vancel, Lauren K. Wareham, Dolly Ann Padovani-Claudio

Sci Rep. 2024; 14: 26159. Published online 2024 Oct 30. doi: 10.1038/s41598-024-75532-9

PMCID:: PMC11525579

Abstract Article PDF–5.9M

Select item 115085477.

C3a Mediates Endothelial Barrier Disruption in Brain-Derived, but Not Retinal, Human Endothelial Cells

Hannah Nora Wolf, Larissa Guempelein, Juliane Schikora, Diana Pauly

Int J Mol Sci. 2024 Oct; 25(20): 11240. Published online 2024 Oct 19. doi: 10.3390/ijms252011240

PMCID:: PMC11508547

Abstract Article PDF–16M

Select item 114908398.

Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux

Daniel T. Hass, Kriti Pandey, Abbi Engel, Noah Horton, Cameron D. Haydinger, Brian M. Robbings, Rayne R. Lim, Martin Sadilek, Qitao Zhang, Gillian A. Gulette, Amy Li, Libin Xu, Jason M.L. Miller, Jennifer R. Chao, James B. Hurley

J Biol Chem. 2024 Oct; 300(10): 107772. Published online 2024 Sep 12. doi: 10.1016/j.jbc.2024.107772

PMCID:: PMC11490839

Abstract Article PDF–4.8M

Select item 114871299.

GWAS-by-subtraction reveals an IOP-independent component of primary open angle glaucoma

Yu Huang, Denis Plotnikov, Huan Wang, Danli Shi, Cong Li, Xueli Zhang, Xiayin Zhang, Shulin Tang, Xianwen Shang, Yijun Hu, Honghua Yu, Hongyang Zhang, Jeremy A. Guggenheim, Mingguang He

Nat Commun. 2024; 15: 8962. Published online 2024 Oct 17. doi: 10.1038/s41467-024-53331-0

PMCID:: PMC11487129

Abstract Article PDF–3.3M

Select item 1147681910.

Bim Expression Influences Choroidal Endothelial Cell Characteristics and Their Response to Therapeutic Intervention

Nader Sheibani, Yong-Seok Song, Mitra Farnoodian, Samay Inampudi, Barbara Hanna, Shoujian Wang, Soesiawati R. Darjatmoko, Christine M. Sorenson

Int J Mol Sci. 2024 Oct; 25(19): 10254. Published online 2024 Sep 24. doi: 10.3390/ijms251910254

PMCID:: PMC11476819

Abstract Article PDF–12M

Select item 1145592111.

YTHDF1-regulated ALOX5 in retinal pigment epithelial cells under hypoxia enhances VEGF expression and promotes viability, migration, and angiogenesis of vascular endothelial cells

Yi Dong, Cheng Qian, Panshi Yan, Guangming Wan

Sci Rep. 2024; 14: 23226. Published online 2024 Oct 5. doi: 10.1038/s41598-024-72388-x

PMCID:: PMC11455921

Abstract Article PDF–4.3M

Select item 1141588412.

Heme: A link between hemorrhage and retinopathy of prematurity progression

Tamás Gáll, Dávid Pethő, Katalin Erdélyi, Virág Egri, Jázon György Balla, Annamária Nagy, Annamária Nagy, Szilárd Póliska, Magnus Gram, Róbert Gábriel, Péter Nagy, József Balla, György Balla

Redox Biol. 2024 Oct; 76: 103316. Published online 2024 Aug 16. doi: 10.1016/j.redox.2024.103316

PMCID:: PMC11415884

Abstract Article PDF–17M

Select item 1139631313.

The Impact of ARMS2 (rs10490924), VEGFA (rs3024997), TNFRSF1B (rs1061622), TNFRSF1A (rs4149576), and IL1B1 (rs1143623) Polymorphisms and Serum Levels on Age-Related Macular Degeneration Development and Therapeutic Responses

Dzastina Cebatoriene, Alvita Vilkeviciute, Greta Gedvilaite-Vaicechauskiene, Monika Duseikaite, Akvile Bruzaite, Loresa Kriauciuniene, Dalia Zaliuniene, Rasa Liutkeviciene

Int J Mol Sci. 2024 Sep; 25(17): 9750. Published online 2024 Sep 9. doi: 10.3390/ijms25179750

PMCID:: PMC11396313

Abstract Article PDF–1.6M

Select item 1137761614.

Clinical and genetic studies for a cohort of patients with Leber congenital amaurosis

Yunyu Zhou, Lijuan Huang, Yan Xie, Wen Liu, Shasha Zhang, Lili Liu, Ping Lin, Ningdong Li

Graefes Arch Clin Exp Ophthalmol. 2024; 262(9): 3029–3038. Published online 2024 Apr 25. doi: 10.1007/s00417-024-06450-9

PMCID:: PMC11377616

Abstract Article PDF–2.4M

Select item 1134617415.

Pigment Epithelium-Derived Factor Binding to VEGFR-1 (Flt-1) Increases the Survival of Retinal Neurons

Jie Meng, Xiu Mei Yang, Oliver Scheer, Johannes Lange, Heidi Müller, Susanne Bürger, Sven Rothemund, Ruaa Younis, Jan D. Unterlauft, Wolfram Eichler

Invest Ophthalmol Vis Sci. 2024 Aug; 65(10): 27. Published online 2024 Aug 21. doi: 10.1167/iovs.65.10.27

PMCID:: PMC11346174

Abstract Article PDF–2.6M

Select item 1134220316.

Therapeutic efficacy of ECs Foxp1 targeting Hif1α-Hk2 glycolysis signal to restrict angiogenesis

Jingjiang Pi, Jie Liu, Huan Chang, Xiaoli Chen, Wenqi Pan, Qi Zhang, Tao Zhuang, Jiwen Liu, Haikun Wang, Brian Tomlinson, Paul Chan, Yu Cheng, Zuoren Yu, Lin Zhang, Zhenlin Zhao, Zhongmin Liu, Jie Liu, Yuzhen Zhang

Redox Biol. 2024 Sep; 75: 103281. Published online 2024 Jul 26. doi: 10.1016/j.redox.2024.103281

PMCID:: PMC11342203

Abstract Article PDF–14M

Select item 1133176417.

Association of outer retinal and choroidal alterations with neuroimaging and clinical features in posterior cortical atrophy

Yuzhu Gao, Ruihan Wang, Kefan Mou, Yifan Zhang, Hanyue Xu, Yilin Liu, Feng Yang, Yunxia Gao, Xiaoyue Wang, Li Bao, Jie Zhang, Qin Chen, Hongbo Yin, Ming Zhang

Alzheimers Res Ther. 2024; 16: 187. Published online 2024 Aug 19. doi: 10.1186/s13195-024-01551-3

PMCID:: PMC11331764

Abstract Article PDF–2.2M

Select item 1130349018.

Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization

Gideon Obasanmi, Manjosh Uppal, Jing Z. Cui, Jeanne Xi, Myeong Jin Ju, Jun Song, Eleanor To, Siqi Li, Wania Khan, Darian Cheng, John Zhu, Lyden Irani, Isa Samad, Julie Zhu, Hyung-Suk Yoo, Alexandre Aubert, Jonathan Stoddard, Martha Neuringer, David J. Granville, Joanne A. Matsubara

Angiogenesis. 2024; 27(3): 351–373. Published online 2024 Mar 18. doi: 10.1007/s10456-024-09909-9