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Items: 1 to 20 of 263

1.
Multi-omics approaches reveal that diffuse midline gliomas present altered DNA replication and are susceptible to replication stress therapy
Anastasia E. Hains, Kashish Chetal, Tsunetoshi Nakatani, Joana G. Marques, Andreas Ettinger, Carlos A. O. Biagi Junior, Adriana Gonzalez-Sandoval, Renjitha Pillai, Mariella G. Filbin, Maria-Elena Torres-Padilla, Ruslan I. Sadreyev, Capucine Van Rechem
Genome Biol. 2024; 25: 319. Published online 2024 Dec 20. doi: 10.1186/s13059-024-03460-y
PMCID:
PMC11660928
AbstractArticlePDF–3.7M
2.
Prospective longitudinal analysis of imaging-based spatiotemporal tumor habitats in glioblastoma, IDH-wild type: implication in patient outcome using multiparametric physiologic MRI
Hye Hyeon Moon, Ji Eun Park, NakYoung Kim, Young-Hoon Kim, Sang Woo Song, Chang Ki Hong, Jeong Hoon Kim, Ho Sung Kim
BMC Cancer. 2024; 24: 1197. Published online 2024 Sep 27. doi: 10.1186/s12885-024-12939-7
PMCID:
PMC11438318
AbstractArticlePDF–1.6M
3.
Glioblastoma mesenchymal subtype enhances antioxidant defence to reduce susceptibility to ferroptosis
Simona D’Aprile, Simona Denaro, Alessandro Lavoro, Saverio Candido, Sebastiano Giallongo, Filippo Torrisi, Lucia Salvatorelli, Giacomo Lazzarino, Angela Maria Amorini, Giuseppe Lazzarino, Gaetano Magro, Daniele Tibullo, Massimo Libra, Cesarina Giallongo, Nunzio Vicario, Rosalba Parenti
Sci Rep. 2024; 14: 20770. Published online 2024 Sep 5. doi: 10.1038/s41598-024-72024-8
PMCID:
PMC11377710
AbstractArticlePDF–4.9M
4.
Pediatric Hemispheric High-Grade Gliomas and H3.3-G34 Mutation: A Review of the Literature on Biological Features and New Therapeutic Strategies
Marta Bonada, Matilde Pittarello, Emerson De Fazio, Alessandro Gans, Paolo Alimonti, Hasan Slika, Federico Legnani, Francesco Di Meco, Betty Tyler
Genes (Basel) 2024 Aug; 15(8): 1038. Published online 2024 Aug 6. doi: 10.3390/genes15081038
PMCID:
PMC11353413
AbstractArticlePDF–4.9M
5.
Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma
Maria F. Gonzalez-Aponte, Anna R. Damato, Laura Lucía Trebucq, Tatiana Simon, Sandra P. Cárdenas-García, Kevin Cho, Gary J. Patti, Diego A. Golombek, Juan José Chiesa, Joshua B. Rubin, Erik D. Herzog
J Neurooncol. Author manuscript; available in PMC 2024 Aug 6.
Published in final edited form as: J Neurooncol. 2024 Feb; 166(3): 419–430. Published online 2024 Jan 26. doi: 10.1007/s11060-023-04535-9
PMCID:
PMC11301575
AbstractArticlePDF–955K
6.
Distribution of EGFR fusions in 35,023 Chinese patients with solid tumors-the frequency, fusion partners and clinical outcome
Haiping Zhang, Julei Wang, Xiaoxiao Li, Dongfeng Zhang, Yingxue Qi, Qin Zhang, Ningning Luo, Xiaoou Wang, Tuo Wang
World J Surg Oncol. 2024; 22: 194. Published online 2024 Jul 25. doi: 10.1186/s12957-024-03463-w
PMCID:
PMC11271172
AbstractArticlePDF–4.7M
7.
Causal relationship between type 2 diabetes and glioblastoma: bidirectional Mendelian randomization analysis
Wei Chen, Taoyuan Zhang, Hui Zhang
Sci Rep. 2024; 14: 16544. Published online 2024 Jul 17. doi: 10.1038/s41598-024-67341-x
PMCID:
PMC11255221
AbstractArticlePDF–3.2M
8.
Targeting Integrin α3 Blocks β1 Maturation, Triggers Endoplasmic Reticulum Stress, and Sensitizes Glioblastoma Cells to TRAIL-Mediated Apoptosis
Yuki Kuranaga, Bing Yu, Satoru Osuka, Hanwen Zhang, Narra S. Devi, Sejong Bae, Erwin G. Van Meir
Cells. 2024 May; 13(9): 753. Published online 2024 Apr 26. doi: 10.3390/cells13090753
PMCID:
PMC11083687
AbstractArticlePDF–3.6M
9.
Germline biallelic BRCA2 pathogenic variants and medulloblastoma: an international cohort study
Svenja Kastellan, Reinhard Kalb, Bia Sajjad, Lisa J. McReynolds, Neelam Giri, David Samuel, Till Milde, Miriam Elbracht, Susanne Holzhauer, Marena R. Niewisch, Christian P. Kratz
J Hematol Oncol. 2024; 17: 26. Published online 2024 Apr 29. doi: 10.1186/s13045-024-01547-4
PMCID:
PMC11057105
AbstractArticlePDF–880K
10.
Depletion of the N6-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4
Limei Deng, Yunbo Di, Caiyun Chen, Juan Xia, Bingxi Lei, Ning Li, Qingyu Zhang
Cell Death Dis. 2024 Mar; 15(3): 181. Published online 2024 Mar 1. doi: 10.1038/s41419-024-06486-z
PMCID:
PMC10907351
AbstractArticlePDF–5.8M
11.
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti–PD-1 Monotherapy: A Report from the International RRD Consortium
Anirban Das, Nicholas R. Fernandez, Adrian Levine, Vanessa Bianchi, Lucie K. Stengs, Jiil Chung, Logine Negm, Jose Rafael Dimayacyac, Yuan Chang, Liana Nobre, Ayse B. Ercan, Santiago Sanchez-Ramirez, Sumedha Sudhaman, Melissa Edwards, Valerie Larouche, David Samuel, An Van Damme, David Gass, David S. Ziegler, Stefan S. Bielack, Carl Koschmann, Shayna Zelcer, Michal Yalon-Oren, Gadi Abede Campino, Tomasz Sarosiek, Kim E. Nichols, Rebecca Loret De Mola, Kevin Bielamowicz, Magnus Sabel, Charlotta A. Frojd, Matthew D. Wood, Jason M. Glover, Yi-Yen Lee, Magimairajan Vanan, Jenny K. Adamski, Sebastien Perreault, Omar Chamdine, Magnus Aasved Hjort, Michal Zapotocky, Fernando Carceller, Erin Wright, Ivana Fedorakova, Alexander Lossos, Ryuma Tanaka, Michael Osborn, Deborah T. Blumenthal, Melyssa Aronson, Ute Bartels, Annie Huang, Vijay Ramaswamy, David Malkin, Adam Shlien, Anita Villani, Peter B. Dirks, Trevor J. Pugh, Gad Getz, Yosef E. Maruvka, Derek S. Tsang, Birgit Ertl-Wagner, Cynthia Hawkins, Eric Bouffet, Daniel A. Morgenstern, Uri Tabori
Cancer Discov. 2024 Feb 8; 14(2): 258–273. Published online 2023 Oct 12. doi: 10.1158/2159-8290.CD-23-0559
PMCID:
PMC10850948
AbstractArticlePDF–17M
12.
Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance
William Echavidre, Jérôme Durivault, Célia Gotorbe, Thays Blanchard, Marina Pagnuzzi, Valérie Vial, Florian Raes, Alexis Broisat, Rémy Villeneuve, Régis Amblard, Nicolas Garnier, Cécile Ortholan, Marc Faraggi, Benjamin Serrano, Vincent Picco, Christopher Montemagno
Cancer Res Commun. 2023 Dec; 3(12): 2483–2496. Published online 2023 Dec 7. doi: 10.1158/2767-9764.CRC-23-0298
PMCID:
PMC10702273
AbstractArticlePDF–16M
13.
Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma
Elena Mariotto, Elena Rampazzo, Roberta Bortolozzi, Fatlum Rruga, Ilaria Zeni, Lorenzo Manfreda, Chiara Marchioro, Martina Canton, Alice Cani, Ruben Magni, Alessandra Luchini, Silvia Bresolin, Giampietro Viola, Luca Persano
Acta Neuropathol Commun. 2023; 11: 183. Published online 2023 Nov 17. doi: 10.1186/s40478-023-01679-7
PMCID:
PMC10655385
AbstractArticlePDF–6.5M
14.
EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma
Antoni Andreu Martija, Alexandra Krauß, Natalie Bächle, Laura Doth, Arne Christians, Damir Krunic, Martin Schneider, Dominic Helm, Rainer Will, Christian Hartmann, Christel Herold-Mende, Andreas von Deimling, Stefan Pusch
Acta Neuropathol Commun. 2023; 11: 177. Published online 2023 Nov 7. doi: 10.1186/s40478-023-01673-z
PMCID:
PMC10629159
AbstractArticlePDF–5.6M
15.
Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells
Johanna Vollmer, Jonas Ecker, Thomas Hielscher, Gintvile Valinciute, Johannes Ridinger, Nora Jamaladdin, Heike Peterziel, Cornelis M. van Tilburg, Ina Oehme, Olaf Witt, Till Milde
J Neurooncol. 2023; 164(3): 617–632. Published online 2023 Oct 3. doi: 10.1007/s11060-023-04445-w
PMCID:
PMC10589189
AbstractArticlePDF–7.4M
16.
Multi-ancestry genome-wide association study of 4069 children with glioma identifies 9p21.3 risk locus
Jon Foss-Skiftesvik, Shaobo Li, Adam Rosenbaum, Christian Munch Hagen, Ulrik Kristoffer Stoltze, Sally Ljungqvist, Ulf Hjalmars, Kjeld Schmiegelow, Libby Morimoto, Adam J de Smith, René Mathiasen, Catherine Metayer, David Hougaard, Beatrice Melin, Kyle M Walsh, Jonas Bybjerg-Grauholm, Anna M Dahlin, Joseph L Wiemels
Neuro Oncol. 2023 Sep; 25(9): 1709–1720. Published online 2023 Feb 22. doi: 10.1093/neuonc/noad042
PMCID:
PMC10484172
AbstractArticlePDF–4.9M
17.
Comprehensive profiling of pathogenic germline large genomic rearrangements in a pan‐cancer analysis
Zhe Sun, Chujie Bai, Miaoyi Su, Haimeng Tang, Xiaoying Wu, Yue Wang, Hua Bao, Xunbiao Liu, Xue Wu, Yang Shao, Bei Xu
Mol Oncol. 2023 Sep; 17(9): 1917–1929. Published online 2023 Apr 12. doi: 10.1002/1878-0261.13430
PMCID:
PMC10483597
AbstractArticlePDF–1.0M
18.
MYC up-regulation confers vulnerability to dual inhibition of CDK12 and CDK13 in high-risk Group 3 medulloblastoma
Consuelo Pitolli, Alberto Marini, Marika Guerra, Marco Pieraccioli, Veronica Marabitti, Fernando Palluzzi, Luciano Giacò, Gianpiero Tamburrini, Francesco Cecconi, Francesca Nazio, Claudio Sette, Vittoria Pagliarini
J Exp Clin Cancer Res. 2023; 42: 214. Published online 2023 Aug 21. doi: 10.1186/s13046-023-02790-2
PMCID:
PMC10440921
AbstractArticlePDF–2.6M
19.
Dynamic susceptibility contrast perfusion-weighted and diffusion-weighted magnetic resonance imaging findings in pilocytic astrocytoma and H3.3 and H3.1 variant diffuse midline glioma, H3K27-altered
Ryo Kurokawa, Mariko Kurokawa, Akira Baba, John Kim, Ashok Srinivasan, Toshio Moritani
PLoS One. 2023; 18(7): e0288412. Published online 2023 Jul 14. doi: 10.1371/journal.pone.0288412
PMCID:
PMC10348548
AbstractArticlePDF–1.5M
20.
Australian genome-wide association study confirms higher female risk for adult glioma associated with variants in the region of CCDC26
Karen Alpen, Claire M Vajdic, Robert J MacInnis, Roger L Milne, Eng-Siew Koh, Elizabeth Hovey, Rosemary Harrup, Fiona Bruinsma, Tuong L Nguyen, Shuai Li, David Joseph, Geza Benke, Pierre-Antoine Dugué, Melissa C Southey, Graham G Giles, Mark Rosenthal, Katharine J Drummond, Anna K Nowak, John L Hopper, Miroslaw Kapuscinski, Enes Makalic
Neuro Oncol. 2023 Jul; 25(7): 1355–1365. Published online 2022 Dec 20. doi: 10.1093/neuonc/noac279
PMCID:
PMC10326491
AbstractArticlePDF–1.0M

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