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Select item 88830001.

Computational pathology aids derivation of microRNA biomarker signals from Cytosponge samples

Neus Masqué-Soler, Marcel Gehrung, Cassandra Kosmidou, Xiaodun Li, Izzuddin Diwan, Conor Rafferty, Elnaz Atabakhsh, Florian Markowetz, Rebecca C. Fitzgerald

EBioMedicine. 2022 Feb; 76: 103814. Published online 2022 Jan 17. doi: 10.1016/j.ebiom.2022.103814

PMCID:: PMC8883000

Abstract Article PDF–2.4M

Select item 83972872.

Insights Into the Oral Microbiome and Barrett's Esophagus Early Detection: A Narrative Review

Zhenzhen Zhang, Grace Curran, Duygu Altinok Dindar, Ying Wu, Hui Wu, Thomas Sharpton, Lianmei Zhao, David Lieberman, Fouad Otaki

Clin Transl Gastroenterol. 2021 Sep; 12(9): e00390. Published online 2021 Aug 26. doi: 10.14309/ctg.0000000000000390

PMCID:: PMC8397287

Abstract Article PDF–211K

Select item 83806863.

Hybrid stomach-intestinal chromatin states underlie human Barrett’s metaplasia

Harshabad Singh, Kyungsik Ha, Jason L. Hornick, Shariq Madha, Paloma Cejas, Kunal Jajoo, Pratik Singh, Paz Polak, Hwajin Lee, Ramesh A. Shivdasani

Gastroenterology. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Gastroenterology. 2021 Sep; 161(3): 924–939.e11. Published online 2021 Jun 4. doi: 10.1053/j.gastro.2021.05.057

PMCID:: PMC8380686

Abstract Article PDF–3.7M

Select item 82869784.

P63 deficiency and CDX2 overexpression lead to Barrett’s-like metaplasia in mouse esophageal epithelium

Yu Fang, Wenbo Li, Xiaoxin Chen

Dig Dis Sci. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Dig Dis Sci. 2021 Dec; 66(12): 4263–4273. Published online 2021 Jan 19. doi: 10.1007/s10620-020-06756-8

PMCID:: PMC8286978

Abstract Article PDF–2.2M

Select item 63095035.

Acidic Bile Salts Induce Epithelial to Mesenchymal Transition via VEGF Signaling in Non-Neoplastic Barrett’s Cells

Qiuyang Zhang, Agoston T. Agoston, Thai H. Pham, Wei Zhang, Xi Zhang, Xiaofang Huo, Sui Peng, Manisha Bajpai, Kiron Das, Robert D. Odze, Stuart J. Spechler, Rhonda F. Souza

Gastroenterology. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Gastroenterology. 2019 Jan; 156(1): 130–144.e10. Published online 2018 Sep 27. doi: 10.1053/j.gastro.2018.09.046

PMCID:: PMC6309503

Abstract Article PDF–1.0M

Select item 61891746.

Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands

Richard Peter Owen, Michael Joseph White, David Tyler Severson, Barbara Braden, Adam Bailey, Robert Goldin, Lai Mun Wang, Carlos Ruiz-Puig, Nicholas David Maynard, Angie Green, Paolo Piazza, David Buck, Mark Ross Middleton, Chris Paul Ponting, Benjamin Schuster-Böckler, Xin Lu

Nat Commun. 2018; 9: 4261. Published online 2018 Oct 15. doi: 10.1038/s41467-018-06796-9

PMCID:: PMC6189174

Abstract Article PDF–2.7M

Select item 59695477.

Bioinformatic analyses of microRNA-targeted genes and microarray-identified genes correlated with Barrett's esophagus

Jing Lv, Jijun Liu, Lei Guo, Jun Zhang, Yan Cheng, Chu Chen, Heping Zhao, Jihan Wang

Cell Cycle. 2018; 17(6): 792–800. Published online 2018 May 18. doi: 10.1080/15384101.2018.1431597

PMCID:: PMC5969547

Abstract Article PDF–1.0M

Select item 58311958.

Transitional basal cells at the squamous-columnar junction generate Barrett’s oesophagus

Ming Jiang, Haiyan Li, Yongchun Zhang, Ying Yang, Rong Lu, Kuancan Liu, Sijie Lin, Xiaopeng Lan, Haikun Wang, Han Wu, Jian Zhu, Zhongren Zhou, Jianming Xu, Dong-Kee Lee, Lanjing Zhang, Yuan-Cho Lee, Jingsong Yuan, Julian A. Abrams, Timothy G. Wang, Antonia R. Sepulveda, Qi Wu, Huaiyong Chen, Xin Sun, Junjun She, Xiaoxin Chen, Jianwen Que

Nature. Author manuscript; available in PMC 2018 Apr 12.

Published in final edited form as: Nature. 2017 Oct 26; 550(7677): 529–533. Published online 2017 Oct 12. doi: 10.1038/nature24269

PMCID:: PMC5831195

Abstract Article PDF–4.1M

Select item 50595669.

Dynamics of SOX2 and CDX2 Expression in Barrett's Mucosa

Rita Barros, Daniela Pereira, Catarina Callé, Vânia Camilo, Ana Isabel Cunha, Leonor David, Raquel Almeida, António Dias-Pereira, Paula Chaves

Dis Markers. 2016; 2016: 1532791. Published online 2016 Sep 27. doi: 10.1155/2016/1532791

PMCID:: PMC5059566

Abstract Article PDF–3.6M

Select item 493405610.

Deoxycholic acid (DCA) confers an intestinal phenotype on esophageal squamous epithelium via induction of the stemness-associated reprogramming factors OCT4 and SOX2

Caifei Shen, Haoxiang Zhang, Pu Wang, Ji Feng, Jingwen Li, Yin Xu, Anran Zhang, Shunzi Shao, Xiaona Yu, Wu Yan, Yiju Xia, Jiali Hu, Dianchun Fang

Cell Cycle. 2016; 15(11): 1439–1449. Published online 2016 Apr 20. doi: 10.1080/15384101.2016.1175252

PMCID:: PMC4934056

Abstract Article PDF–1.2M

Select item 483091811.

Localization of specialized intestinal metaplasia and the molecular alterations in Barrett's esophagus in a Japanese population: an analysis of biopsy samples based on the “Seattle” biopsy protocol

Shota Fukui, Jiro Watari, Toshihiko Tomita, Takahisa Yamasaki, Takuya Okugawa, Takashi Kondo, Tomoaki Kono, Katsuyuki Tozawa, Hisatomo Ikehara, Yoshio Ohda, Tadayuki Oshima, Hirokazu Fukui, Kiron M. Das, Hiroto Miwa

Hum Pathol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Hum Pathol. 2016 May; 51: 32–40. Published online 2016 Jan 7. doi: 10.1016/j.humpath.2015.12.013

PMCID:: PMC4830918

Abstract Article PDF–246K

Select item 461467712.

Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4

Maria E Vega, Véronique Giroux, Mitsuteru Natsuizaka, Mingen Liu, Andres J Klein-Szanto, Douglas B Stairs, Hiroshi Nakagawa, Kenneth K Wang, Timothy C Wang, John P Lynch, Anil K Rustgi

Cell Cycle. 2014 Dec 15; 13(24): 3857–3866. Published online 2015 Jan 3. doi: 10.4161/15384101.2014.972875

PMCID:: PMC4614677

Abstract Article PDF–892K

Select item 445081113.

Expression of Bile Acid Transporting Proteins in Barrett’s Esophagus and Esophageal Adenocarcinoma

Katerina Dvorak, George S. Watts, Lois Ramsey, Hana Holubec, Claire M. Payne, Carol Bernstein, Gareth J. Jenkins, Richard E. Sampliner, Anil Prasad, Harinder S. Garewal, Harris Bernstein

Am J Gastroenterol. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Am J Gastroenterol. 2009 Feb; 104(2): 302–309. Published online 2009 Jan 27. doi: 10.1038/ajg.2008.85

PMCID:: PMC4450811

Abstract Article PDF–558K

Select item 415122014.

Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett’s metaplasia

David H. Wang, Anjana Tiwari, Monica E. Kim, Nicholas J. Clemons, Nanda L. Regmi, William A. Hodges, David M. Berman, Elizabeth A. Montgomery, D. Neil Watkins, Xi Zhang, Qiuyang Zhang, Chunfa Jie, Stuart J. Spechler, Rhonda F. Souza

J Clin Invest. 2014 Sep 2; 124(9): 3767–3780. Published online 2014 Aug 1. doi: 10.1172/JCI66603

PMCID:: PMC4151220

Abstract Article PDF–5.1M

Select item 377802815.

Dpp signaling determines regional stem cell identity in the regenerating adult Drosophila gastrointestinal tract

Hongjie Li, Yanyan Qi, Heinrich Jasper

Cell Rep. Author manuscript; available in PMC 2013 Sep 19.

Published in final edited form as: Cell Rep. 2013 Jul 11; 4(1): 10–18. Published online 2013 Jun 27. doi: 10.1016/j.celrep.2013.05.040

PMCID:: PMC3778028

Abstract Article PDF–3.1M

Select item 375011816.

Molecular Mechanism of Barrett’s Esophagus

Hao Chen, Yu Fang, Whitney Tevebaugh, Roy C. Orlando, Nicholas J. Shaheen, Xiaoxin Chen

Dig Dis Sci. Author manuscript; available in PMC 2013 Aug 22.

Published in final edited form as: Dig Dis Sci. 2011 Dec; 56(12): 3405–3420. Published online 2011 Oct 8. doi: 10.1007/s10620-011-1885-6

PMCID:: PMC3750118

Abstract Article PDF–338K

Select item 354468417.

Clinicopathologic characteristics of high expression of Bmi-1 in esophageal adenocarcinoma and squamous cell carcinoma

Bonnie Choy, Santhoshi Bandla, Yinglin Xia, Dongfeng Tan, Arjun Pennathur, James D Luketich, Tony E Godfrey, Jeffrey H Peters, Jun Sun, Zhongren Zhou

BMC Gastroenterol. 2012; 12: 146. Published online 2012 Oct 18. doi: 10.1186/1471-230X-12-146

PMCID:: PMC3544684

Abstract Article PDF–1.8M

Select item 342257718.

Aberrant Epithelial-Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia

David H. Wang, Nicholas J. Clemons, Tomoharu Miyashita, Adam J. Dupuy, Wei Zhang, Anette Szczepny, Ian M. Corcoran-Schwartz, Daniel L. Wilburn, Elizabeth A. Montgomery, Jean S. Wang, Nancy A. Jenkins, Neal A. Copeland, John W. Harmon, Wayne A. Phillips, D. Neil Watkins

Gastroenterology. Author manuscript; available in PMC 2012 Aug 18.

Published in final edited form as: Gastroenterology. 2010 May; 138(5): 1810–1822. Published online 2010 Feb 4. doi: 10.1053/j.gastro.2010.01.048

PMCID:: PMC3422577

Abstract Article PDF–4.0M

Select item 331792619.

The Immune Cell Composition in Barrett's Metaplastic Tissue Resembles That in Normal Duodenal Tissue

Alexandra Lind, Peter D. Siersema, Johannes G. Kusters, Jan A. M. Van der Linden, Edward F. Knol, Leo Koenderman

PLoS One. 2012; 7(4): e33899. Published online 2012 Apr 3. doi: 10.1371/journal.pone.0033899

PMCID:: PMC3317926

Abstract Article PDF–563K

Select item 318933820.

Prevalence of Barrett's Esophagus in first degree relatives of patients with esophageal adenocarcinoma

Arpad Juhasz, Sumeet K Mittal, Tommy H Lee, Caishu Deng, Amitabh Chak, Henry T Lynch

J Clin Gastroenterol. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: J Clin Gastroenterol. 2011 Nov; 45(10): 867–871. doi: 10.1097/MCG.0b013e31821f44a8

PMCID:: PMC3189338

Abstract Article PDF–112K

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