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Items: 1 to 20 of 500

1.
Iron metabolism in a mouse model of hepatocellular carcinoma
Dilay Yilmaz, Umesh Tharehalli, Rossana Paganoni, Paul Knoop, Andreas Gruber, Yuexin Chen, Rui Dong, Frank Leithäuser, Thomas Seufferlein, Kerstin Leopold, André Lechel, Maja Vujić Spasić
Sci Rep. 2025; 15: 2180. Published online 2025 Jan 16. doi: 10.1038/s41598-025-86486-x
PMCID:
PMC11739418
ArticlePDF–5.1M
2.
Comparative genomic analysis unveiling the mutational landscape associated with premalignant lesions and early-stage gastric cardia cancer
Guangda Wang, Liang Liu, Yang Zhao, Yan Lin, Limian Er
Medicine (Baltimore) 2025 Jan 10; 104(2): e40332. Published online 2025 Jan 10. doi: 10.1097/MD.0000000000040332
PMCID:
PMC11731115
ArticlePDF–2.2M
3.
Precision medicine in diagnosis, prognosis, and disease monitoring of bone and soft tissue sarcomas using liquid biopsy: a systematic review
Maria Anna Smolle, Markus G. Seidel, Karl Kashofer, Bernadette Liegl-Atzwanger, Patrick Sadoghi, Daniel A. Müller, Andreas Leithner
Arch Orthop Trauma Surg. 2025; 145(1): 121. Published online 2025 Jan 11. doi: 10.1007/s00402-024-05711-w
PMCID:
PMC11724793
ArticlePDF–1.0M
4.
The phase I/II eNRGy trial: Zenocutuzumab in patients with cancers harboring NRG1 gene fusions
Dong-Wan Kim, Alison M Schram, Antoine Hollebecque, Kazumi Nishino, Teresa Macarulla, Sun Young Rha, Michaël Duruisseaux, Stephen V Liu, Mohammed Najeeb Al Hallak, Kumiko Umemoto, Claas Wesseler, James M Cleary, Christoph Springfeld, Cindy Neuzillet, Andrew Joe, Shekeab Jauhari, Jim Ford, Koichi Goto
Future Oncol. 2024; 20(16): 1057–1067. Published online 2024 Feb 13. doi: 10.2217/fon-2023-0824
PMCID:
PMC11721935
ArticlePDF–2.9M
5.
FOXP3+/CD8+ ratio associated with aggressive behavior in RUNX3‐methylated diffuse esophagogastric junction tumor
Suguru Maruyama, Yu Imamura, Tasuku Toihata, Ikumi Haraguchi, Manabu Takamatsu, Makiko Yamashita, Yuichiro Nakashima, Eiji Oki, Kenichi Taguchi, Manabu Yamamoto, Shinji Mine, Akihiko Okamura, Jun Kanamori, Souya Nunobe, Takeshi Sano, Shigehisa Kitano, Tetsuo Noda, Masayuki Watanabe
Cancer Sci. 2025 Jan; 116(1): 178–191. Published online 2024 Oct 23. doi: 10.1111/cas.16373
PMCID:
PMC11711055
ArticlePDF–1.4M
6.
Molecularly redefining small bowel adenocarcinoma to accelerate precision patient care – protocol of a multicenter observational cohort biomarker study
Rasmus Haunstrup Døssing, Julia Johanna Almer Broman, Colm J. O’Rourke, Elizaveta Mitkina Tabaksblat, Jesper Bøje Andersen, Carsten Palnæs Hansen, Tim Svenstrup Poulsen, Estrid V. S. Høgdall, Jakob Hagen Vasehus Schou, Dan Høgdall
BMC Cancer. 2025; 25: 22. Published online 2025 Jan 7. doi: 10.1186/s12885-024-13369-1
PMCID:
PMC11707884
ArticlePDF–2.2M
7.
Comprehensive analysis of inhibin-β A as a potential biomarker for gastrointestinal tract cancers through bioinformatics approaches
Rohit Kumar Verma, Prashant Kumar Srivastava, Ashutosh Singh
Sci Rep. 2025; 15: 1090. Published online 2025 Jan 7. doi: 10.1038/s41598-024-72679-3
PMCID:
PMC11707248
ArticlePDF–13M
8.
Circulating tumor DNA predicts recurrence and survival in patients with resectable gastric and gastroesophageal junction cancer
Cecilie Riis Iden, Salah Mohammad Mustafa, Nadia Øgaard, Tenna Henriksen, Sarah Østrup Jensen, Lise Barlebo Ahlborn, Kristian Egebjerg, Lene Baeksgaard, Rajendra Singh Garbyal, Mette Kjølhede Nedergaard, Michael Patrick Achiam, Claus Lindbjerg Andersen, Morten Mau-Sørensen
Gastric Cancer. 2025; 28(1): 83–95. Published online 2024 Oct 5. doi: 10.1007/s10120-024-01556-9
PMCID:
PMC11706848
ArticlePDF–3.2M
9.
Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer
Lukas Klein, Mengyu Tu, Niklas Krebs, Laura Urbach, Daniela Grimm, Muhammad Umair Latif, Frederike Penz, Anna Blandau, Xueyan Wu, Rebecca Diya Samuel, Stefan Küffer, Florian Wegwitz, Nathan Chan, Kazeera Aliar, Foram Vyas, Uday Kishore, Elisabeth Hessmann, Andreas Trumpp, Elisa Espinet, Argyris Papantonis, Rama Khokha, Volker Ellenrieder, Barbara T. Grünwald, Shiv K. Singh
Nat Commun. 2025; 16: 335. Published online 2025 Jan 6. doi: 10.1038/s41467-024-55330-7
PMCID:
PMC11704331
ArticlePDF–9.7M
10.
Single cell and spatial analysis of immune-hot and immune-cold tumours identifies fibroblast subtypes associated with distinct immunological niches and positive immunotherapy response
Benjamin H. Jenkins, Ian Tracy, Maria Fernanda S. D. Rodrigues, Melanie J. L. Smith, Begoña R. Martinez, Mark Edmond, Sangeetha Mahadevan, Anjali Rao, Hailing Zong, Kai Liu, Abhishek Aggarwal, Li Li, Lauri Diehl, Emma V. King, Jamie G. Bates, Christopher J. Hanley, Gareth J. Thomas
Mol Cancer. 2025; 24: 3. Published online 2025 Jan 6. doi: 10.1186/s12943-024-02191-9
PMCID:
PMC11702232
ArticlePDF–14M
11.
Liver-specific gene PGRMC1 blocks c-Myc-induced hepatocarcinogenesis through ER stress-independent PERK activation
Fubo Ji, Jianjuan Zhang, Liping Mao, Yaqi Tan, Meihua Ye, Xianglei He, Yongzhi Zhao, Jiaxin Liu, Yan Zhang, Nachuan Zhang, Jiong Shi, Jianing Yan, Xiujun Cai, Bin Zhao, Jianping Jin, Pinglong Xu, Stephanie Roessler, Xin Zheng, Junfang Ji
Nat Commun. 2025; 16: 50. Published online 2025 Jan 2. doi: 10.1038/s41467-024-55745-2
PMCID:
PMC11696091
ArticlePDF–8.2M
12.
Diacylglycerol kinase alpha regulates post-hepatectomy liver regeneration
Hiroki Nakamoto, Shunsuke Shichi, Chisato Shirakawa, Takuto Suzuki, Hidemitsu Kitamura, Akinobu Taketomi
Sci Rep. 2025; 15: 555. Published online 2025 Jan 2. doi: 10.1038/s41598-024-84403-2
PMCID:
PMC11696009
ArticlePDF–5.2M
13.
Prognostic Value of Retinoblastoma in Small Intestinal Adenocarcinoma: A Multicenter Retrospective Study
Sun-Young Jun, Seung-Mo Hong, Kee-Taek Jang
J Korean Med Sci. 2024 Dec 30; 39(50): e335. Published online 2024 Dec 5. doi: 10.3346/jkms.2024.39.e335
PMCID:
PMC11685279
ArticlePDF–6.0M
14.
DNAJB4/HLJ1 deficiency sensitizes diethylnitrosamine-induced hepatocarcinogenesis with peritumoral STAT3 activation
Wei-Jia Luo, Wei-Lun Hsu, Chih-Yun Lu, Min-Hui Chien, Jung-Hsuan Chang, Kang-Yi Su
Cell Biol Toxicol. 2025; 41(1): 20. Published online 2024 Dec 30. doi: 10.1007/s10565-024-09978-y
PMCID:
PMC11685265
ArticlePDF–10M
15.
AKR1B10 and digestive tumors development: a review
Yao Shen, Ailin Qiu, Xin Huang, Xiaosha Wen, Sundar Shehzadi, Yan He, Qian Hu, Jian Zhang, Dixian Luo, Shenghui Yang
Front Immunol. 2024; 15: 1462174. Published online 2024 Dec 16. doi: 10.3389/fimmu.2024.1462174
PMCID:
PMC11682995
ArticlePDF–1.4M
16.
Comprehensive in silico CpG methylation analysis in hepatocellular carcinoma identifies tissue- and tumor-type specific marks disconnected from gene expression
Idoia Bilbao, Miriam Recalde, Fabrice Daian, José Maria Herranz, María Elizalde, Mercedes Iñarrairaegui, Matteo Canale, Maite G. Fernández-Barrena, Andrea Casadei-Gardini, Bruno Sangro, Matías A. Ávila, Manuel F. Landecho Acha, Carmen Berasain, María Arechederra
J Physiol Biochem. 2024; 80(4): 865–879. Published online 2024 Sep 21. doi: 10.1007/s13105-024-01045-8
PMCID:
PMC11682006
ArticlePDF–3.8M
17.
OSBPL10‐CNBP axis mediates hypoxia‐induced pancreatic cancer development
Yishu Huang, Ronghao Zhang, Shuyang Fan, Minmin Shi, Xiaomei Tang, Xinjing Wang, Xiaxing Deng
Biofactors. 2025 Jan-Feb; 51(1): e2124. Published online 2024 Sep 27. doi: 10.1002/biof.2124
PMCID:
PMC11681314
ArticlePDF–15M
18.
Microbiome and metabolome analysis in smoking and non-smoking pancreatic ductal adenocarcinoma patients
Xiao Liang, Yiqing Zhu, Yongqi Bu, Min Dong, Guoming Zhang, Changxu Chen, Haoyun Tang, Limei Wang, Peng Wang, Yifan Wang, Ruiguang Ma, Xinyu Chen, Jun Wang, Guoxian Yu, Ning Zhong, Lixiang Li, Zhen Li
BMC Microbiol. 2024; 24: 541. Published online 2024 Dec 27. doi: 10.1186/s12866-024-03688-5
PMCID:
PMC11673369
ArticlePDF–6.0M
19.
Interplay between gut microbiome, host genetic and epigenetic modifications in MASLD and MASLD-related hepatocellular carcinoma
Suki Ha, Vincent Wai-Sun Wong, Xiang Zhang, Jun Yu
Gut. 2024 Jun; 74(1): e332398. Published online 2024 Jun 29. doi: 10.1136/gutjnl-2024-332398
PMCID:
PMC11671994
ArticlePDF–4.9M
20.
Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity
Quanhui Dai, Kristina Preusse, Danni Yu, Rhett A. Kovall, Konrad Thorner, Xinhua Lin, Raphael Kopan
PLoS Genet. 2024 Dec; 20(12): e1011486. Published online 2024 Dec 12. doi: 10.1371/journal.pgen.1011486
PMCID:
PMC11670933
ArticlePDF–3.9M

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