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Items: 1 to 20 of 39

1.
Pattern of somatic mutations in patients with Waldenström macroglobulinemia or IgM monoclonal gammopathy of undetermined significance
Marzia Varettoni, Silvia Zibellini, Irene Defrancesco, Virginia Valeria Ferretti, Ettore Rizzo, Luca Malcovati, Anna Gallì, Matteo Giovanni Della Porta, Emanuela Boveri, Luca Arcaini, Chiara Candido, Marco Paulli, Mario Cazzola
Haematologica. 2017 Dec; 102(12): 2077–2085. Prepublished online 2017 Oct 5. doi: 10.3324/haematol.2017.172718
PMCID:
PMC5709107
AbstractArticlePDF–1.0M
2.
Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenstrom's Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutations Status
Michele Cea, Antonia Cagnetta, Chirag Acharya, Prakrati Acharya, Yu-Tzu Tai, Guang Yang, Davide Lovera, Debora Soncini, Maurizio Miglino, Giulio Fraternali-Orcioni, Luca Mastracci, Alessio Nencioni, Fabrizio Montecucco, Alberto Ballestrero, Teru Hideshima, Dharminder Chauhan, Marco Gobbi, Roberto M. Lemoli, Nikhil Munshi, Steven P. Treon, Kenneth C. Anderson
Clin Cancer Res. Author manuscript; available in PMC 2018 Jan 17.
Published in final edited form as: Clin Cancer Res. 2016 Dec 15; 22(24): 6099–6109. Published online 2016 Jun 10. doi: 10.1158/1078-0432.CCR-16-0630
PMCID:
PMC5771267
AbstractArticlePDF–731K
3.
Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström's Macroglobulinemia: Correlation with MYD88 L265P Somatic Mutation Status, Clinical Features, and Outcome
Loizos Petrikkos, Marie-Christine Kyrtsonis, Maria Roumelioti, George Georgiou, Anna Efthymiou, Tatiana Tzenou, Panayiotis Panayiotidis
Biomed Res Int. 2014; 2014: 809103. Published online 2014 Aug 14. doi: 10.1155/2014/809103
PMCID:
PMC4147361
AbstractArticlePDF–590K
4.
Consequences of the recurrent MYD88L265P somatic mutation for B cell tolerance
James Q. Wang, Yogesh S. Jeelall, Bruce Beutler, Keisuke Horikawa, Christopher C. Goodnow
J Exp Med. 2014 Mar 10; 211(3): 413–426. doi: 10.1084/jem.20131424
PMCID:
PMC3949567
AbstractArticlePDF–3.1M
5.
Transcriptome sequencing reveals a profile that corresponds to genomic variants in Waldenström macroglobulinemia
Zachary R. Hunter, Lian Xu, Guang Yang, Nicholas Tsakmaklis, Josephine M. Vos, Xia Liu, Jie Chen, Robert J. Manning, Jiaji G. Chen, Philip Brodsky, Christopher J. Patterson, Joshua Gustine, Toni Dubeau, Jorge J. Castillo, Kenneth C. Anderson, Nikhil M. Munshi, Steven P. Treon
Blood. 2016 Aug 11; 128(6): 827–838. Prepublished online 2016 Jun 14. doi: 10.1182/blood-2016-03-708263
PMCID:
PMC4982454
AbstractArticle
6.
Clonal architecture of CXCR4 WHIM-like mutations in Waldenström Macroglobulinaemia
Lian Xu, Zachary R. Hunter, Nicholas Tsakmaklis, Yang Cao, Guang Yang, Jie Chen, Xia Liu, Sandra Kanan, Jorge J. Castillo, Yu-Tzu Tai, James L. Zehnder, Jennifer R. Brown, Ruben D. Carrasco, Ranjana Advani, Jean M. Sabile, Kimon Argyropoulos, M. Lia Palomba, Enrica Morra, Alessandra Trojani, Antonino Greco, Alessandra Tedeschi, Marzia Varettoni, Luca Arcaini, Nikhil M. Munshi, Kenneth C. Anderson, Steven P. Treo
Br J Haematol. Author manuscript; available in PMC 2017 Apr 28.
Published in final edited form as: Br J Haematol. 2016 Mar; 172(5): 735–744. Published online 2015 Dec 13. doi: 10.1111/bjh.13897
PMCID:
PMC5409813
AbstractArticlePDF–664K
7.
The importance of the genomic landscape in Waldenström's Macroglobulinemia for targeted therapeutical interventions
Antonio Sacco, Adriano Fenotti, Loredana Affò, Stefano Bazzana, Domenico Russo, Marco Presta, Michele Malagola, Antonella Anastasia, Marina Motta, Christopher J. Patterson, Giuseppe Rossi, Luisa Imberti, Steven P. Treon, Irene M. Ghobrial, Aldo M. Roccaro
Oncotarget. 2017 May 23; 8(21): 35435–35444. Published online 2017 Mar 11. doi: 10.18632/oncotarget.16130
PMCID:
PMC5471067
AbstractArticlePDF–1.1M
8.
Complete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and lgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient
Nagaradona Harindranath, Inna S. Goldfarb, Hideyuki Ikematsu, Samuele E. Burastero, Ronald L. Wilder, Abner L. Notkins, Paolo Casali
Int Immunol. Author manuscript; available in PMC 2015 Nov 4.
Published in final edited form as: Int Immunol. 1991 Sep; 3(9): 865–875. doi: 10.1093/intimm/3.9.865
PMCID:
PMC4632984
AbstractArticlePDF–1.8M
9.
Insights into the genomic landscape of MYD88 wild-type Waldenström macroglobulinemia
Zachary R. Hunter, Lian Xu, Nickolas Tsakmaklis, Maria G. Demos, Amanda Kofides, Cristina Jimenez, Gloria G. Chan, Jiaji Chen, Xia Liu, Manit Munshi, Joshua Gustine, Kirsten Meid, Christopher J. Patterson, Guang Yang, Toni Dubeau, Mehmet K. Samur, Jorge J. Castillo, Kenneth C. Anderson, Nikhil C. Munshi, Steven P. Treon
Blood Adv. 2018 Nov 13; 2(21): 2937–2946. Published online 2018 Nov 6. doi: 10.1182/bloodadvances.2018022962
PMCID:
PMC6234368
AbstractArticlePDF–1.4M
10.
Rare Circulating Cells in Familial Waldenström Macroglobulinemia Displaying the MYD88 L265P Mutation Are Enriched by Epstein-Barr Virus Immortalization
Maroulio Pertesi, Perrine Galia, Nicolas Nazaret, Maxime Vallée, Laurent Garderet, Xavier Leleu, Hervé Avet-Loiseau, Matthieu Foll, Graham Byrnes, Joel Lachuer, James D. McKay, Charles Dumontet
PLoS One. 2015; 10(9): e0136505. Published online 2015 Sep 9. doi: 10.1371/journal.pone.0136505
PMCID:
PMC4564105
AbstractArticlePDF–266K
11.
Recent updates in the indolent lymphomas: Update on marginal zone lymphoma and Waldenström's macroglobulinemia
Karima Amaador, Catherine Thieblemont, Judith Trotman, Monique C. Minnema
Hematol Oncol. 2024 Nov; 42(6): e3210. Published online 2023 Jul 17. doi: 10.1002/hon.3210
PMCID:
PMC11590047
AbstractArticlePDF–234K
12.
Genomic Landscape of Waldenström Macroglobulinemia and Its Impact on Treatment Strategies
Steven P. Treon, Lian Xu, Maria Luisa Guerrera, Cristina Jimenez, Zachary R. Hunter, Xia Liu, Maria Demos, Joshua Gustine, Gloria Chan, Manit Munshi, Nicholas Tsakmaklis, Jiaji G. Chen, Amanda Kofides, Romanos Sklavenitis-Pistofidis, Mark Bustoros, Andrew Keezer, Kirsten Meid, Christopher J. Patterson, Antonio Sacco, Aldo Roccaro, Andrew R. Branagan, Guang Yang, Irene M. Ghobrial, Jorge J. Castillo
J Clin Oncol. 2020 Apr 10; 38(11): 1198–1208. Published online 2020 Feb 21. doi: 10.1200/JCO.19.02314
PMCID:
PMC7351339
AbstractArticlePDF–848K
13.
B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS
Kristin Schmidt, Ulrike Sack, Robin Graf, Wiebke Winkler, Oliver Popp, Philipp Mertins, Thomas Sommermann, Christine Kocks, Klaus Rajewsky
Front Immunol. 2020; 11: 602868. Published online 2020 Dec 1. doi: 10.3389/fimmu.2020.602868
PMCID:
PMC7747680
AbstractArticlePDF–1010K
14.
Resistance Mutations to BTK Inhibitors Originate From the NF-κB but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway
C. I. Edvard Smith, Jan A. Burger
Front Immunol. 2021; 12: 689472. Published online 2021 Jun 10. doi: 10.3389/fimmu.2021.689472
PMCID:
PMC8222783
AbstractArticlePDF–7.6M
15.
Determination of MYD88L265P mutation fraction in IgM monoclonal gammopathies
Tina Bagratuni, Athina Markou, Dimitrios Patseas, Nefeli Mavrianou-Koutsoukou, Foteini Aktypi, Christine Ivy Liacos, Aimilia D. Sklirou, Foteini Theodorakakou, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Ioannis P. Trougakos, Evi Lianidou, Evangelos Terpos, Efstathios Kastritis, Meletios A. Dimopoulos
Blood Adv. 2022 Jan 11; 6(1): 189–199. Published online 2022 Jan 7. doi: 10.1182/bloodadvances.2021005354
PMCID:
PMC8753203
AbstractArticlePDF–1.2M
16.
Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma
Sara Rodriguez, Jon Celay, Ibai Goicoechea, Cristina Jimenez, Cirino Botta, Maria-José Garcia-Barchino, Juan-Jose Garces, Marta Larrayoz, Susana Santos, Diego Alignani, Amaia Vilas-Zornoza, Cristina Perez, Sonia Garate, Sarai Sarvide, Aitziber Lopez, Hans-Christian Reinhardt, Yolanda R. Carrasco, Isidro Sanchez-Garcia, Maria-Jose Larrayoz, Maria-Jose Calasanz, Carlos Panizo, Felipe Prosper, Jose-Maria Lamo-Espinosa, Marina Motta, Alessandra Tucci, Antonio Sacco, Massimo Gentile, Sara Duarte, Helena Vitoria, Catarina Geraldes, Artur Paiva, Noemi Puig, Ramon Garcia-Sanz, Aldo M. Roccaro, Gema Fuerte, Jesus F. San Miguel, Jose-Angel Martinez-Climent, Bruno Paiva
Sci Adv. 2022 Jan; 8(3): eabl4644. Published online 2022 Jan 19. doi: 10.1126/sciadv.abl4644
PMCID:
PMC8769557
AbstractArticlePDF–4.1M
17.
Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia
Sabrin Tahri, Tarek H. Mouhieddine, Robert Redd, Luisa Lampe, Katarina I. Nilsson, Habib El-Khoury, Nang Kham Su, Amin H. Nassar, Elio Adib, Govind Bindra, Sarah Abou Alaiwi, Lorenzo Trippa, David P. Steensma, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial, Adam S. Sperling
Blood Adv. 2022 Apr 12; 6(7): 2230–2235. Published online 2022 Apr 1. doi: 10.1182/bloodadvances.2021004926
PMCID:
PMC9006277
AbstractArticlePDF–971K
18.
MYD88 Mutations: Transforming the Landscape of IgM Monoclonal Gammopathies
Miguel Alcoceba, María García-Álvarez, Alejandro Medina, Rebeca Maldonado, Verónica González-Calle, María Carmen Chillón, María Eugenia Sarasquete, Marcos González, Ramón García-Sanz, Cristina Jiménez
Int J Mol Sci. 2022 May; 23(10): 5570. Published online 2022 May 16. doi: 10.3390/ijms23105570
PMCID:
PMC9141891
AbstractArticlePDF–916K
19.
Concurrent Waldenstrom’s Macroglobulinemia and Myelodysplastic Syndrome with a Sequent t(10;13)(p13;q22) Translocation
Peter A. DeRosa, Kyle C. Roche, Victor E. Nava, Sunita Singh, Min-Ling Liu, Anita Agarwal
Curr Oncol. 2022 Jul; 29(7): 4587–4592. Published online 2022 Jun 29. doi: 10.3390/curroncol29070363
PMCID:
PMC9325113
AbstractArticlePDF–771K
20.
Waldenström macroglobulinemia whole genome reveals prolonged germinal center activity and late copy number aberrations
Kylee H. Maclachlan, Tina Bagratuni, Efstathios Kastritis, Bachisio Ziccheddu, Sydney Lu, Venkata Yellapantula, Chris Famulare, Kimon Argyropoulos, Andriy Derkach, Elli Papaemmanuil, Ahmet Dogan, Alexander Lesokhin, Saad Z. Usmani, C. Ola Landgren, Lia M. Palomba, Francesco Maura, Meletios A. Dimopoulos
Blood Adv. 2023 Mar 28; 7(6): 971–981. Published online 2022 Nov 6. doi: 10.1182/bloodadvances.2022008876
PMCID:
PMC10027506
AbstractArticlePDF–692K

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