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Items: 1 to 20 of 273

1.
Gene Variant Frequencies of IDO1, IDO2, TDO, and KMO in Substance Use Disorder Cohorts
Lindsey Contella, Christopher L. Farrell, Luigi Boccuto, Alain Litwin, Marion L. Snyder
Genes (Basel) 2024 Nov; 15(11): 1388. Published online 2024 Oct 29. doi: 10.3390/genes15111388
PMCID:
PMC11594152
ArticlePDF–1009K
2.
Molecular mechanisms and therapeutic significance of Tryptophan Metabolism and signaling in cancer
Jing Yan, Di Chen, Zi Ye, Xuqiang Zhu, Xueyuan Li, Henan Jiao, Mengjiao Duan, Chaoli Zhang, Jingliang Cheng, Lixia Xu, Hongjiang Li, Dongming Yan
Mol Cancer. 2024; 23: 241. Published online 2024 Oct 30. doi: 10.1186/s12943-024-02164-y
PMCID:
PMC11523861
ArticlePDF–3.3M
3.
The aryl hydrocarbon receptor and FOS mediate cytotoxicity induced by Acinetobacter baumannii
Chun Kew, Cristian Prieto-Garcia, Anshu Bhattacharya, Manuela Tietgen, Craig R. MacNair, Lindsey A. Carfrae, João Mello-Vieira, Stephan Klatt, Yi-Lin Cheng, Rajeshwari Rathore, Elise Gradhand, Ingrid Fleming, Man-Wah Tan, Stephan Göttig, Volkhard A. J. Kempf, Ivan Dikic
Nat Commun. 2024; 15: 7939. Published online 2024 Sep 11. doi: 10.1038/s41467-024-52118-7
PMCID:
PMC11390868
ArticlePDF–2.2M
4.
Indoleamine Dioxygenase and Tryptophan Dioxygenase Activities are regulated through GAPDH- and Hsp90-dependent Control of their Heme Levels
Pranjal Biswas, Yue Dai, Dennis J. Stuehr
Free Radic Biol Med. Author manuscript; available in PMC 2024 Sep 11.
Published in final edited form as: Free Radic Biol Med. 2022 Feb 20; 180: 179–190. Published online 2022 Jan 17. doi: 10.1016/j.freeradbiomed.2022.01.008
PMCID:
PMC11389873
ArticlePDF–4.4M
5.
Targeting amino acid-metabolizing enzymes for cancer immunotherapy
Yvonne Grobben
Front Immunol. 2024; 15: 1440269. Published online 2024 Aug 14. doi: 10.3389/fimmu.2024.1440269
PMCID:
PMC11359565
ArticlePDF–11M
6.
Multi-Omics Integrative Analysis to Reveal the Impacts of Shewanella algae on the Development and Lifespan of Marine Nematode Litoditis marina
Yiming Xue, Beining Xue, Liusuo Zhang
Int J Mol Sci. 2024 Aug; 25(16): 9111. Published online 2024 Aug 22. doi: 10.3390/ijms25169111
PMCID:
PMC11354469
ArticlePDF–16M
7.
Kynurenines as a Novel Target for the Treatment of Inflammatory Disorders
Adrian Mor, Anna Tankiewicz-Kwedlo, Marianna Ciwun, Janina Lewkowicz, Dariusz Pawlak
Cells. 2024 Aug; 13(15): 1259. Published online 2024 Jul 26. doi: 10.3390/cells13151259
PMCID:
PMC11311768
ArticlePDF–1.7M
8.
Visualization of the hepatic and renal cell uptake and trafficking of tetrahedral DNA origami in tumour
Shitai Zhu, Hongzhen Peng, Huating Kong, Qinglong Yan, Kai Xia, Lihua Wang, Ying Zhu, Shihua Luo
Cell Prolif. 2024 Aug; 57(8): e13643. Published online 2024 Apr 4. doi: 10.1111/cpr.13643
PMCID:
PMC11294413
ArticlePDF–6.0M
9.
Eyesi direct ophthalmoscope simulator: an effective training tool for medical undergraduates
Canying Liu, Jicheng Lin, Siting Wu, Yingting Zhu, Yuxian Zou, Qi Zhang, Zhidong Li, Yehong Zhuo, Yiqing Li
BMC Med Educ. 2024; 24: 783. Published online 2024 Jul 20. doi: 10.1186/s12909-024-05780-w
PMCID:
PMC11265108
ArticlePDF–3.0M
10.
Elevated serum kynurenic acid in individuals with first-episode psychosis and insufficient response to antipsychotics
Alex Hatzimanolis, Stefania Foteli, Lida-Alkisti Xenaki, Mirjana Selakovic, Stefanos Dimitrakopoulos, Ilias Vlachos, Ioannis Kosteletos, Rigas-Filippos Soldatos, Maria Gazouli, Stylianos Chatzipanagiotou, Nikos Stefanis
Schizophrenia (Heidelb) 2024; 10(1): 61. Published online 2024 Jul 10. doi: 10.1038/s41537-024-00483-z
PMCID:
PMC11237022
ArticlePDF–1.3M
11.
The role of the kynurenine pathway in cardiovascular disease
Yuehang Yang, Xing Liu, Xinyi Liu, Chiyang Xie, Jiawei Shi
Front Cardiovasc Med. 2024; 11: 1406856. Published online 2024 May 31. doi: 10.3389/fcvm.2024.1406856
PMCID:
PMC11176437
ArticlePDF–1.2M
12.
Craniofacial syndromes and class III phenotype: common genotype fingerprints? A scoping review and meta-analysis
Maria Cristina Faria-Teixeira, Cristina Tordera, Francisco Salvado e Silva, António Vaz-Carneiro, Alejandro Iglesias-Linares
Pediatr Res. 2024; 95(6): 1455–1475. Published online 2024 Feb 12. doi: 10.1038/s41390-023-02907-5
PMCID:
PMC11126392
ArticlePDF–2.2M
13.
Unveiling the Role of Tryptophan 2,3-Dioxygenase in the Angiogenic Process
Marta Cecchi, Cecilia Anceschi, Angela Silvano, Maria Luisa Coniglio, Aurora Chinnici, Lucia Magnelli, Andrea Lapucci, Anna Laurenzana, Astrid Parenti
Pharmaceuticals (Basel) 2024 May; 17(5): 558. Published online 2024 Apr 27. doi: 10.3390/ph17050558
PMCID:
PMC11124529
ArticlePDF–5.6M
14.
Nanovesicular Mediation of the Gut–Brain Axis by Probiotics: Insights into Irritable Bowel Syndrome
Radha Santonocito, Letizia Paladino, Alessandra Maria Vitale, Giuseppa D’Amico, Francesco Paolo Zummo, Paolo Pirrotta, Samuele Raccosta, Mauro Manno, Salvatore Accomando, Francesco D’Arpa, Francesco Carini, Rosario Barone, Francesca Rappa, Antonella Marino Gammazza, Fabio Bucchieri, Francesco Cappello, Celeste Caruso Bavisotto
Biology (Basel) 2024 May; 13(5): 296. Published online 2024 Apr 25. doi: 10.3390/biology13050296
PMCID:
PMC11117693
ArticlePDF–3.2M
15.
Kynurenine pathway metabolism evolves with development of preclinical and scleroderma-associated pulmonary arterial hypertension
Catherine E. Simpson, Anjira S. Ambade, Robert Harlan, Aurelie Roux, Susan Aja, David Graham, Ami A. Shah, Laura K. Hummers, Anna R. Hemnes, Jane A. Leopold, Evelyn M. Horn, Erika S. Berman-Rosenzweig, Gabriele Grunig, Micheala A. Aldred, John Barnard, Suzy A. A. Comhair, W. H. Wilson Tang, Megan Griffiths, Franz Rischard, Robert P. Frantz, Serpil C. Erzurum, Gerald J. Beck, Nicholas S. Hill, Stephen C. Mathai, Paul M. Hassoun, Rachel L. Damico, and the PVDOMICS Study Group
Am J Physiol Lung Cell Mol Physiol. 2023 Nov 1; 325(5): L617–L627. Published online 2023 Oct 3. doi: 10.1152/ajplung.00177.2023
PMCID:
PMC11068393
Article
16.
Adaptive UAV Navigation Method Based on AHRS
Yin Lu, Zhipeng Li, Jun Xiong, Ke Lv
Sensors (Basel) 2024 Apr; 24(8): 2518. Published online 2024 Apr 14. doi: 10.3390/s24082518
PMCID:
PMC11053795
ArticlePDF–4.7M
17.
Exploring a repurposed candidate with dual hIDO1/hTDO2 inhibitory potential for anticancer efficacy identified through pharmacophore-based virtual screening and in vitro evaluation
Nourhan M. Aboomar, Omar Essam, Afnan Hassan, Ahmad R. Bassiouny, Reem K. Arafa
Sci Rep. 2024; 14: 9386. Published online 2024 Apr 24. doi: 10.1038/s41598-024-59353-4
PMCID:
PMC11039737
ArticlePDF–4.9M
18.
DLX3-Dependent Regulation of Ion Transporters and Carbonic Anhydrases Is Crucial for Enamel Mineralization
Olivier Duverger, Takahiro Ohara, Paul W Bible, Angela Zah, Maria I Morasso
J Bone Miner Res. Author manuscript; available in PMC 2024 Apr 18.
Published in final edited form as: J Bone Miner Res. 2017 Mar; 32(3): 641–653. Published online 2017 Feb 23. doi: 10.1002/jbmr.3022
PMCID:
PMC11025043
ArticlePDF–3.8M
19.
The introduction of immunosuppressor (TDO inhibitor) significantly improved the efficacy of irinotecan in treating hepatocellular carcinoma
Qingqing Liu, Shixian Hua, Xinyi Wang, Feihong Chen, Shaohua Gou
Cancer Immunol Immunother. 2021 Feb; 70(2): 497–508. Published online 2020 Aug 25. doi: 10.1007/s00262-020-02697-3
PMCID:
PMC10991124
ArticlePDF–2.0M
20.
Off-target depletion of plasma tryptophan by allosteric inhibitors of BCKDK
Caitlyn E. Bowman, Michael D. Neinast, Cholsoon Jang, Jiten Patel, Megan C. Blair, Emily T. Mirek, William O. Jonsson, Qingwei Chu, Lauren Merlo, Laura Mandik-Nayak, Tracy G. Anthony, Joshua D. Rabinowitz, Zolt Arany
Version 1. bioRxiv. Preprint. 2024 Mar 10. doi: 10.1101/2024.03.05.582974
PMCID:
PMC10942310
ArticlePDF–950K

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