PMC Articles for MedGen (Select 863898) - PMC

Select item 110987421.

Endogenous aldehyde-induced DNA–protein crosslinks are resolved by transcription-coupled repair

Yasuyoshi Oka, Yuka Nakazawa, Mayuko Shimada, Tomoo Ogi

Nat Cell Biol. 2024; 26(5): 784–796. Published online 2024 Apr 10. doi: 10.1038/s41556-024-01401-2

PMCID:: PMC11098742

Select item 98677492.

SPRTN patient variants cause global-genome DNA-protein crosslink repair defects

Pedro Weickert, Hao-Yi Li, Maximilian J. Götz, Sophie Dürauer, Denitsa Yaneva, Shubo Zhao, Jacqueline Cordes, Aleida C. Acampora, Ignasi Forne, Axel Imhof, Julian Stingele

Nat Commun. 2023; 14: 352. Published online 2023 Jan 21. doi: 10.1038/s41467-023-35988-1

PMCID:: PMC9867749

Abstract Article PDF–5.4M

Select item 92406423.

Mechanisms and Regulation of DNA-Protein Crosslink Repair During DNA Replication by SPRTN Protease

Megan Perry, Gargi Ghosal

Front Mol Biosci. 2022; 9: 916697. Published online 2022 Jun 15. doi: 10.3389/fmolb.2022.916697

PMCID:: PMC9240642

Abstract Article PDF–1.5M

Select item 54168364.

Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis

Reeja S. Maskey, Karen S. Flatten, Cynthia J. Sieben, Kevin L. Peterson, Darren J. Baker, Hyun-Ja Nam, Myoung Shin Kim, Thomas C. Smyrk, Yusuke Kojima, Yuka Machida, Annyoceli Santiago, Jan M. van Deursen, Scott H. Kaufmann, Yuichi J. Machida

Nucleic Acids Res. 2017 May 5; 45(8): 4564–4576. Published online 2017 Feb 13. doi: 10.1093/nar/gkx107

PMCID:: PMC5416836

Abstract Article PDF–6.4M

Select item 51287275.

Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair

Bruno Vaz, Marta Popovic, Joseph A. Newman, John Fielden, Hazel Aitkenhead, Swagata Halder, Abhay Narayan Singh, Iolanda Vendrell, Roman Fischer, Ignacio Torrecilla, Neele Drobnitzky, Raimundo Freire, David J. Amor, Paul J. Lockhart, Benedikt M. Kessler, Gillies W. McKenna, Opher Gileadi, Kristijan Ramadan

Mol Cell. 2016 Nov 17; 64(4): 704–719. doi: 10.1016/j.molcel.2016.09.032

PMCID:: PMC5128727

Abstract Article

Select item 51287266.

Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN

Julian Stingele, Roberto Bellelli, Ferdinand Alte, Graeme Hewitt, Grzegorz Sarek, Sarah L. Maslen, Susan E. Tsutakawa, Annabel Borg, Svend Kjær, John A. Tainer, J. Mark Skehel, Michael Groll, Simon J. Boulton

Mol Cell. 2016 Nov 17; 64(4): 688–703. doi: 10.1016/j.molcel.2016.09.031

PMCID:: PMC5128726

Abstract Article PDF–3.5M

Select item 51276447.

SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks

Jaime Lopez-Mosqueda, Karthik Maddi, Stefan Prgomet, Sissy Kalayil, Ivana Marinovic-Terzic, Janos Terzic, Ivan Dikic

eLife. 2016; 5: e21491. Published online 2016 Nov 17. doi: 10.7554/eLife.21491

PMCID:: PMC5127644

Abstract Article PDF–2.6M

Select item 27684518.

DKC1 overexpression associated with prostate cancer progression

P Sieron, C Hader, J Hatina, R Engers, A Wlazlinski, M Müller, W A Schulz

Br J Cancer. 2009 Oct 20; 101(8): 1410–1416. Published online 2009 Sep 15. doi: 10.1038/sj.bjc.6605299

PMCID:: PMC2768451

Abstract Article PDF–559K

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