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Items: 1 to 20 of 27

1.
Steroids-producing nodules: a two-layered adrenocortical nodular structure as a precursor lesion of cortisol-producing adenoma
Tazuru Fukumoto, Hironobu Umakoshi, Norifusa Iwahashi, Tatsuki Ogasawara, Maki Yokomoto-Umakoshi, Hiroki Kaneko, Masamichi Fujita, Naohiro Uchida, Hiroshi Nakao, Namiko Kawamura, Yayoi Matsuda, Ryuichi Sakamoto, Takashi Miyazawa, Masahide Seki, Masatoshi Eto, Yoshinao Oda, Yutaka Suzuki, Seishi Ogawa, Yoshihiro Ogawa
eBioMedicine. 2024 May; 103: 105087. Published online 2024 Apr 2. doi: 10.1016/j.ebiom.2024.105087
PMCID:
PMC11121169
AbstractArticlePDF–3.7M
2.
Double somatic mutations in CTNNB1 and GNA11 in an aldosterone-producing adenoma
Kazutaka Nanba, Amy R. Blinder, Aaron M. Udager, Yuusuke Hirokawa, Takayoshi Miura, Hiroshi Okuno, Koki Moriyoshi, Yuto Yamazaki, Hironobu Sasano, Akihiro Yasoda, Noriko Satoh-Asahara, William E. Rainey, Tetsuya Tagami
Front Endocrinol (Lausanne) 2024; 15: 1286297. Published online 2024 Mar 5. doi: 10.3389/fendo.2024.1286297
PMCID:
PMC10948454
AbstractArticlePDF–6.0M
3.
Primary aldosteronism: spatial multi-omics mapping of genotype-dependent heterogeneity and tumor expansion of aldosterone-producing adenomas
Siyuan Gong, Na Sun, Lucie S Meyer, Martina Tetti, Christina Koupourtidou, Stefan Krebs, Giacomo Masserdotti, Helmut Blum, William E. Rainey, Martin Reincke, Axel Walch, Tracy Ann Williams
Hypertension. Author manuscript; available in PMC 2024 Jul 1.
Published in final edited form as: Hypertension. 2023 Jul; 80(7): 1555–1567. Published online 2023 May 1. doi: 10.1161/HYPERTENSIONAHA.123.20921
PMCID:
PMC10330203
AbstractArticlePDF–3.8M
4.
Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution
Norifusa Iwahashi, Hironobu Umakoshi, Tsugio Seki, Celso E Gomez-Sanchez, Kuniaki Mukai, Makoto Suematsu, Yuta Umezawa, Mototsugu Oya, Takeo Kosaka, Masahide Seki, Yutaka Suzuki, Yutaka Horiuchi, Yoshihiro Ogawa, Koshiro Nishimoto
J Clin Endocrinol Metab. 2022 Sep; 107(9): 2439–2448. Published online 2022 Jul 5. doi: 10.1210/clinem/dgac394
PMCID:
PMC9387688
AbstractArticle
5.
Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause
Junhua Zhou, Elena A. B. Azizan, Claudia P. Cabrera, Fabio L. Fernandes-Rosa, Sheerazed Boulkroun, Giulia Argentesi, Emily Cottrell, Laurence Amar, Xilin Wu, Sam O’Toole, Emily Goodchild, Alison Marker, Russell Senanayake, Sumedha Garg, Tobias Åkerström, Samuel Backman, Suzanne Jordan, Satyamaanasa Polubothu, Daniel M. Berney, Anna Gluck, Kate E. Lines, Rajesh V. Thakker, Antoinette Tuthill, Caroline Joyce, Juan Pablo Kaski, Fiona E. Karet Frankl, Lou A. Metherell, Ada E. D. Teo, Mark Gurnell, Laila Parvanta, William M. Drake, Eva Wozniak, David Klinzing, Jyn Ling Kuan, Zenia Tiang, Celso E. Gomez Sanchez, Per Hellman, Roger S. Y. Foo, Charles A. Mein, Veronica A. Kinsler, Peyman Björklund, Helen L. Storr, Maria-Christina Zennaro, Morris J. Brown
Nat Genet. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Nat Genet. 2021 Sep; 53(9): 1360–1372. Published online 2021 Aug 12. doi: 10.1038/s41588-021-00906-y
PMCID:
PMC9082578
AbstractArticlePDF–3.2M
6.
Cellular Senescence in Adrenocortical Biology and Its Disorders
Xin Gao, Faping Li, Bin Liu, Yuxiong Wang, Yishu Wang, Honglan Zhou
Cells. 2021 Dec; 10(12): 3474. Published online 2021 Dec 9. doi: 10.3390/cells10123474
PMCID:
PMC8699888
AbstractArticlePDF–1.5M
7.
Primary aldosteronism: molecular medicine meets public health
Elena A. B. Azizan, William M. Drake, Morris J. Brown
Nat Rev Nephrol. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Nat Rev Nephrol. 2023 Aug 23 : 10.1038/s41581-023-00753-6. Published online 2023 Aug 23. doi: 10.1038/s41581-023-00753-6
PMCID:
PMC7615304
AbstractArticlePDF–2.2M
8.
18-Oxocortisol Synthesis in Aldosterone-Producing Adrenocortical Adenoma and Significance of KCNJ5 Mutation Status
Yuta Tezuka, Yuto Yamazaki, Masaaki Kitada, Ryo Morimoto, Masataka Kudo, Kazumasa Seiji, Kei Takase, Yoshihide Kawasaki, Koji Mitsuzuka, Akihiro Ito, Jun Nishikawa, Noriko Asai, Yasuhiro Nakamura, Celso E. Gomez-Sanchez, Sadayoshi Ito, Mari Dezawa, Hironobu Sasano, Fumitoshi Satoh
Hypertension. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Hypertension. 2019 Jun; 73(6): 1283–1290. doi: 10.1161/HYPERTENSIONAHA.118.12064
PMCID:
PMC6758910
AbstractArticlePDF–488K
9.
PRIMARY ALDOSTERONISM: KCNJ5 MUTATIONS AND ADRENOCORTICAL CELL GROWTH
Yuhong Yang, Celso E. Gomez-Sanchez, Diana Jaquin, Elke Tatjana Aristizabal Prada, Lucie S. Meyer, Thomas Knösel, Holger Schneider, Felix Beuschlein, Martin Reincke, Tracy Ann Williams
Hypertension. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Hypertension. 2019 Oct; 74(4): 809–816. Published online 2019 Aug 26. doi: 10.1161/HYPERTENSIONAHA.119.13476
PMCID:
PMC6739168
AbstractArticlePDF–1.4M
10.
CELLULAR AND GENETIC CAUSES OF IDIOPATHIC HYPERALDOSTERONISM
Kei Omata, Fumitoshi Satoh, Ryo Morimoto, Sadayoshi Ito, Yuto Yamazaki, Yasuhiro Nakamura, Sharath K. Anand, Zeng Guo, Michael Stowasser, Hironobu Sasano, Scott A. Tomlins, William E. Rainey
Hypertension. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Hypertension. 2018 Oct; 72(4): 874–880. doi: 10.1161/HYPERTENSIONAHA.118.11086
PMCID:
PMC6207209
AbstractArticlePDF–573K
11.
Role of Cryptochrome-1 and Cryptochrome-2 in Aldosterone-Producing Adenomas and Adrenocortical Cells
Martina Tetti, Isabella Castellano, Francesca Veneziano, Corrado Magnino, Franco Veglio, Paolo Mulatero, Silvia Monticone
Int J Mol Sci. 2018 Jun; 19(6): 1675. Published online 2018 Jun 5. doi: 10.3390/ijms19061675
PMCID:
PMC6032245
AbstractArticlePDF–4.4M
12.
Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-producing Adenoma
Kazuhiro Kobuke, Kenji Oki, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Haruya Ohno, Kiyotaka Itcho, Yoko Yoshii, Masayasu Yoneda, Noboru Hattori
Hypertension. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Hypertension. 2018 Jan; 71(1): 125–133. Published online 2017 Nov 6. doi: 10.1161/HYPERTENSIONAHA.117.10205
PMCID:
PMC5730498
AbstractArticlePDF–2.2M
13.
On the effect of hyperaldosteronism-inducing mutations in Na/K pumps
Dylan J. Meyer, Craig Gatto, Pablo Artigas
J Gen Physiol. 2017 Nov 6; 149(11): 1009–1028. doi: 10.1085/jgp.201711827
PMCID:
PMC5677107
AbstractArticlePDF–2.1M
14.
Histopathological and genetic characterization of aldosterone-producing adenomas with concurrent subclinical cortisol hypersecretion: a case series
Francesco Fallo, Isabella Castellano, Celso E. Gomez-Sanchez, Yara Rhayem, Catia Pilon, Valentina Vicennati, Donatella Santini, Valeria Maffeis, Ambrogio Fassina, Paolo Mulatero, Felix Beuschlein, Martin Reincke
Endocrine. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: Endocrine. 2017 Dec; 58(3): 503–512. Published online 2017 Apr 12. doi: 10.1007/s12020-017-1295-4
PMCID:
PMC5638684
AbstractArticlePDF–676K
15.
Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism
Koshiro Nishimoto, Minae Koga, Tsugio Seki, Kenji Oki, Elise P. Gomez-Sanchez, Celso E. Gomez-Sanchez, Mitsuhide Naruse, Tomokazu Sakaguchi, Shinya Morita, Takeo Kosaka, Mototsugu Oya, Tadashi Ogishima, Masanori Yasuda, Makoto Suematsu, Yasuaki Kabe, Masao Omura, Tetsuo Nishikawa, Kuniaki Mukai
Mol Cell Endocrinol. Author manuscript; available in PMC 2018 Feb 5.
Published in final edited form as: Mol Cell Endocrinol. 2017 Feb 5; 441: 124–133. Published online 2016 Oct 14. doi: 10.1016/j.mce.2016.10.014
PMCID:
PMC5470036
AbstractArticlePDF–2.5M
16.
Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin)
Ada Ee Der Teo, Sumedha Garg, Timothy Isaac Johnson, Wanfeng Zhao, Junhua Zhou, Celso Enrique Gomez-Sanchez, Mark Gurnell, Morris Jonathan Brown
Hypertension. 2017 Jun; 69(6): 1207–1216. Published online 2017 May 10. doi: 10.1161/HYPERTENSIONAHA.117.09156
PMCID:
PMC5424579
AbstractArticlePDF–889K
17.
Minireview: Potassium Channels and Aldosterone Dysregulation: Is Primary Aldosteronism a Potassium Channelopathy?
Celso E. Gomez-Sanchez, Kenji Oki
Endocrinology. 2014 Jan; 155(1): 47–55. Published online 2013 Nov 18. doi: 10.1210/en.2013-1733
PMCID:
PMC5398635
AbstractArticle
18.
Immunohistochemical, genetic and clinical characterization of sporadic aldosterone-producing adenomas
Silvia Monticone, Isabella Castellano, Karine Versace, Barbara Lucatello, Franco Veglio, Celso E. Gomez-Sanchez, Tracy A. Williams, Paolo Mulatero
Mol Cell Endocrinol. Author manuscript; available in PMC 2016 Aug 15.
Published in final edited form as: Mol Cell Endocrinol. 2015 Aug 15; 411: 146–154. Published online 2015 May 6. doi: 10.1016/j.mce.2015.04.022
PMCID:
PMC4474471
AbstractArticlePDF–878K
19.
LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal
Lalarukh Haris Shaikh, Junhua Zhou, Ada E. D. Teo, Sumedha Garg, Sudeshna Guha Neogi, Nichola Figg, Giles S. Yeo, Haixiang Yu, Janet J. Maguire, Wanfeng Zhao, Martin R. Bennett, Elena A. B. Azizan, Anthony P. Davenport, Grahame McKenzie, Morris J. Brown
J Clin Endocrinol Metab. 2015 Jun; 100(6): E836–E844. Published online 2015 Apr 27. doi: 10.1210/jc.2015-1734
PMCID:
PMC4454794
AbstractArticle
20.
DACH1, a Zona Glomerulosa Selective Gene in the Human Adrenal, Activates Transforming Growth Factor-β Signaling and Suppresses Aldosterone Secretion
Junhua Zhou, Lalarukh Haris Shaikh, Sudeshna G. Neogi, Ian McFarlane, Wanfeng Zhao, Nichola Figg, Cheryl A. Brighton, Carmela Maniero, Ada E.D. Teo, Elena A. B. Azizan, Morris J. Brown
Hypertension. 2015 May; 65(5): 1103–1110. Published online 2015 Apr 8. doi: 10.1161/HYP.0000000000000025
PMCID:
PMC4387203
AbstractArticlePDF–1014K

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