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Select item 65909891.

Mouse TRPA1 function and membrane localization are modulated by direct interactions with cholesterol

Justyna B Startek, Brett Boonen, Alejandro López-Requena, Ariel Talavera, Yeranddy A Alpizar, Debapriya Ghosh, Nele Van Ranst, Bernd Nilius, Thomas Voets, Karel Talavera

eLife. 2019; 8: e46084. Published online 2019 Jun 11. doi: 10.7554/eLife.46084

PMCID:: PMC6590989

Abstract Article PDF–5.3M

Select item 65892362.

TRPV1 and TRPA1 in Lung Inflammation and Airway Hyperresponsiveness Induced by Fine Particulate Matter (PM_2.5)

Mengmeng Xu, Yanbei Zhang, Muyun Wang, Hai Zhang, Yuqing Chen, Ian M. Adcock, Kian Fan Chung, Jinhan Mo, Yinping Zhang, Feng Li

Oxid Med Cell Longev. 2019; 2019: 7450151. Published online 2019 Jun 2. doi: 10.1155/2019/7450151

PMCID:: PMC6589236

Abstract Article PDF–5.2M

Select item 65657503.

Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development

Sonoko Takahashi, Azusa Ishida, Akiharu Kubo, Hiroshi Kawasaki, Sotaro Ochiai, Manabu Nakayama, Haruhiko Koseki, Masayuki Amagai, Takaharu Okada

Sci Rep. 2019; 9: 8625. Published online 2019 Jun 13. doi: 10.1038/s41598-019-44866-0

PMCID:: PMC6565750

Abstract Article PDF–16M

Select item 59323854.

Immunization Elicits Antigen-Specific Antibody Sequestration in Dorsal Root Ganglia Sensory Neurons

Manojkumar Gunasekaran, Prodyot K. Chatterjee, Andrew Shih, Gavin H. Imperato, Meghan Addorisio, Gopal Kumar, Annette Lee, John F. Graf, Dan Meyer, Michael Marino, Christopher Puleo, Jeffrey Ashe, Maureen A. Cox, Tak W. Mak, Chad Bouton, Barbara Sherry, Betty Diamond, Ulf Andersson, Thomas R. Coleman, Christine N. Metz, Kevin J. Tracey, Sangeeta S. Chavan

Front Immunol. 2018; 9: 638. Published online 2018 Apr 16. doi: 10.3389/fimmu.2018.00638

PMCID:: PMC5932385

Abstract Article PDF–3.0M

Select item 58475265.

Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice

Cyril Rivat, Chamroeun Sar, Ilana Mechaly, Jean-Philippe Leyris, Lucie Diouloufet, Corinne Sonrier, Yann Philipson, Olivier Lucas, Sylvie Mallié, Antoine Jouvenel, Adrien Tassou, Henri Haton, Stéphanie Venteo, Jean-Philippe Pin, Eric Trinquet, Fabienne Charrier-Savournin, Alexandre Mezghrani, Willy Joly, Julie Mion, Martine Schmitt, Alexandre Pattyn, Frédéric Marmigère, Pierre Sokoloff, Patrick Carroll, Didier Rognan, Jean Valmier

Nat Commun. 2018; 9: 1042. Published online 2018 Mar 12. doi: 10.1038/s41467-018-03496-2

PMCID:: PMC5847526

Abstract Article PDF–2.5M

Select item 53908716.

Lysophosphatidic acid‐induced itch is mediated by signalling of LPA₅ receptor, phospholipase D and TRPA1/TRPV1

Hiroki Kittaka, Kunitoshi Uchida, Naomi Fukuta, Makoto Tominaga

J Physiol. 2017 Apr 15; 595(8): 2681–2698. Published online 2017 Mar 22. doi: 10.1113/JP273961

PMCID:: PMC5390871

Abstract Article PDF–1.5M

Select item 50483747.

TRPA1 and TRPV1 contribute to iodine antiseptics‐associated pain and allergy

Deyuan Su, Hong Zhao, Jinsheng Hu, Dan Tang, Jianmin Cui, Ming Zhou, Jian Yang, Shu Wang

EMBO Rep. 2016 Oct; 17(10): 1422–1430. Published online 2016 Aug 26. doi: 10.15252/embr.201642349

PMCID:: PMC5048374

Abstract Article PDF–1.8M

Select item 43016998.

Spinal blockage of P/Q- or N-type voltage-gated calcium channels modulates functional and symptomatic changes related to haemorrhagic cystitis in mice

R B M Silva, N D M Sperotto, E L Andrade, T C B Pereira, C E Leite, A H de Souza, M R Bogo, F B Morrone, M V Gomez, M M Campos

Br J Pharmacol. 2015 Feb; 172(3): 924–939. Published online 2014 Dec 15. doi: 10.1111/bph.12966

PMCID:: PMC4301699

Abstract Article PDF–2.6M

Select item 41802739.

Upregulation of the Transient Receptor Potential Ankyrin 1 Ion Channel in the Inflamed Human and Mouse Colon and Its Protective Roles

József Kun, István Szitter, Ágnes Kemény, Anikó Perkecz, László Kereskai, Krisztina Pohóczky, Áron Vincze, Szilárd Gódi, Imre Szabó, János Szolcsányi, Erika Pintér, Zsuzsanna Helyes

PLoS One. 2014; 9(9): e108164. Published online 2014 Sep 29. doi: 10.1371/journal.pone.0108164

PMCID:: PMC4180273

Abstract Article PDF–2.1M

Select item 416952510.

PIWI Proteins Are Dispensable for Mouse Somatic Development and Reprogramming of Fibroblasts into Pluripotent Stem Cells

Ee-Chun Cheng, Dongwan Kang, Zhong Wang, Haifan Lin

PLoS One. 2014; 9(9): e97821. Published online 2014 Sep 19. doi: 10.1371/journal.pone.0097821

PMCID:: PMC4169525

Abstract Article PDF–6.3M

Select item 409015011.

Increasing Maternal or Post-Weaning Folic Acid Alters Gene Expression and Moderately Changes Behavior in the Offspring

Subit Barua, Kathryn K. Chadman, Salomon Kuizon, Diego Buenaventura, Nathan W. Stapley, Felicia Ruocco, Umme Begum, Sara R. Guariglia, W. Ted Brown, Mohammed A. Junaid

PLoS One. 2014; 9(7): e101674. Published online 2014 Jul 9. doi: 10.1371/journal.pone.0101674

PMCID:: PMC4090150

Abstract Article PDF–635K

Select item 405837812.

TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis

Jennifer J. DeBerry, Erica S. Schwartz, Brian M. Davis

Pain. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Pain. 2014 Jul; 155(7): 1280–1287. Published online 2014 Apr 2. doi: 10.1016/j.pain.2014.03.023

PMCID:: PMC4058378

Abstract Article PDF–1.1M

Select item 391623113.

Uncoupling of Molecular Maturation from Peripheral Target Innervation in Nociceptors Expressing a Chimeric TrkA/TrkC Receptor

Svetlana Gorokhova, Stéphane Gaillard, Louise Urien, Pascale Malapert, Wassim Legha, Grégory Baronian, Jean-Pierre Desvignes, Serge Alonso, Aziz Moqrich

PLoS Genet. 2014 Feb; 10(2): e1004081. Published online 2014 Feb 6. doi: 10.1371/journal.pgen.1004081

PMCID:: PMC3916231

Abstract Article PDF–5.6M

Select item 379147914.

Species differences and molecular determinant of TRPA1 cold sensitivity

Jun Chen, Dawon Kang, Jing Xu, Marc Lake, James O. Hogan, Chaohong Sun, Karl Walter, Betty Yao, Donghee Kim

Nat Commun. 2013 Sep 27; 4: 2501. Published online 2013 Sep 27. doi: 10.1038/ncomms3501

PMCID:: PMC3791479

Abstract Article PDF–718K

Select item 356557315.

In vitro pharmacological characterization of a novel TRPA1 antagonist and proof of mechanism in a human dental pulp model

Eva Nyman, Bo Franzén, Andreas Nolting, Göran Klement, Gang Liu, Maria Nilsson, Annika Rosén, Charlotta Björk, Dirk Weigelt, Patrik Wollberg, Paul Karila, Patrick Raboisson

J Pain Res. 2013; 6: 59–70. Published online 2013 Jan 30. doi: 10.2147/JPR.S37567

PMCID:: PMC3565573

Abstract Article PDF–902K

Select item 341745916.

Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice

Angelo A Izzo, Raffaele Capasso, Gabriella Aviello, Francesca Borrelli, Barbara Romano, Fabiana Piscitelli, Laura Gallo, Francesco Capasso, Pierangelo Orlando, Vincenzo Di Marzo

Br J Pharmacol. 2012 Jun; 166(4): 1444–1460. doi: 10.1111/j.1476-5381.2012.01879.x