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Select item 68481881.

RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2

Barbara Nicol, Sara A. Grimm, Frédéric Chalmel, Estelle Lecluze, Maëlle Pannetier, Eric Pailhoux, Elodie Dupin-De-Beyssat, Yann Guiguen, Blanche Capel, Humphrey H.-C. Yao

Nat Commun. 2019; 10: 5116. Published online 2019 Nov 11. doi: 10.1038/s41467-019-13060-1

PMCID:: PMC6848188

Abstract Article PDF–13M

Select item 65978582.

Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency

Hongwei Ma, Fan Yang, Michael R. Butler, Jacob Rapp, Yun-Zheng Le, Xi-Qin Ding

eNeuro. 2019 May-Jun; 6(3): ENEURO.0119-19.2019. Prepublished online 2019 Jun 10. Published online 2019 Jun 27. doi: 10.1523/ENEURO.0119-19.2019

PMCID:: PMC6597858

Abstract Article PDF–4.0M

Select item 61871273.

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

Harry A. T. Pritchard, Paulo W. Pires, Evan Yamasaki, Pratish Thakore, Scott Earley

Proc Natl Acad Sci U S A. 2018 Oct 9; 115(41): E9745–E9752. Published online 2018 Sep 4. doi: 10.1073/pnas.1804593115

PMCID:: PMC6187127

Abstract Article PDF–1.3M

Select item 21203854.

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues

J Cell Biol. 1995 Mar 1; 128(5): 893–904. doi: 10.1083/jcb.128.5.893

PMCID:: PMC2120385

Summary PDF–3.1M

Select item 3943595.

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

H Takeshima, T Yamazawa, T Ikemoto, H Takekura, M Nishi, T Noda, M Iino

EMBO J. 1995 Jul 3; 14(13): 2999–3006. doi: 10.1002/j.1460-2075.1995.tb07302.x

PMCID:: PMC394359

Summary Page Browse PDF–1.8M

Select item 70586036.

miR-221 and -222 target CACNA1C and KCNJ5 leading to altered cardiac ion channel expression and current density

Stephanie Binas, Maria Knyrim, Julia Hupfeld, Udo Kloeckner, Sindy Rabe, Sigrid Mildenberger, Katja Quarch, Nicole Strätz, Danny Misiak, Michael Gekle, Claudia Grossmann, Barbara Schreier

Cell Mol Life Sci. 2020 Mar; 77(5): 903–918. Published online 2019 Jul 16. doi: 10.1007/s00018-019-03217-y

PMCID:: PMC7058603

Abstract Article PDF–1.5M

Select item 67641157.

Panax Notoginseng Saponins Protect Cardiac Myocytes Against Endoplasmic Reticulum Stress and Associated Apoptosis Through Mediation of Intracellular Calcium Homeostasis

Jun Chen, Rui Xue, Li Li, Li Li Xiao, Jiahong Shangguan, Wenjing Zhang, Xueyang Bai, Gangqiong Liu, Ling Li

Front Pharmacol. 2019; 10: 1013. Published online 2019 Sep 20. doi: 10.3389/fphar.2019.01013

PMCID:: PMC6764115

Abstract Article PDF–2.6M

Select item 65260168.

Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice

Qianqian Wang, Chao Wang, Bo Wang, Qirui Shen, Leilei Qiu, Shuaijun Zou, Tao Wang, Guoyan Liu, Beilei Wang, Liming Zhang

PeerJ. 2019; 7: e6942. Published online 2019 May 16. doi: 10.7717/peerj.6942

PMCID:: PMC6526016

Abstract Article PDF–21M

Select item 64836359.

Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2

Francisco J. Alvarado, J. Martijn Bos, Zhiguang Yuchi, Carmen R. Valdivia, Jonathan J. Hernández, Yan-Ting Zhao, Dawn S. Henderlong, Yan Chen, Talia R. Booher, Cherisse A. Marcou, Filip Van Petegem, Michael J. Ackerman, Héctor H. Valdivia

JCI Insight. 2019 Apr 4; 4(7): e126544. Published online 2019 Apr 4. doi: 10.1172/jci.insight.126544

PMCID:: PMC6483635

Abstract Article PDF–5.7M

Select item 612368510.

A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca²⁺ sensitivity

Takashi Murayama, Haruo Ogawa, Nagomi Kurebayashi, Seiko Ohno, Minoru Horie, Takashi Sakurai

Commun Biol. 2018; 1: 98. Published online 2018 Jul 23. doi: 10.1038/s42003-018-0103-x

PMCID:: PMC6123685

Abstract Article PDF–2.0M

Select item 610770111.

Organelle Optogenetics: Direct Manipulation of Intracellular Ca²⁺ Dynamics by Light

Toshifumi Asano, Hiroyuki Igarashi, Toru Ishizuka, Hiromu Yawo

Front Neurosci. 2018; 12: 561. Published online 2018 Aug 17. doi: 10.3389/fnins.2018.00561

PMCID:: PMC6107701

Abstract Article PDF–1.5M

Select item 589998912.

Ca²⁺ signalling in mouse urethral smooth muscle in situ: role of Ca²⁺ stores and Ca²⁺ influx mechanisms

Bernard T. Drumm, Benjamin E. Rembetski, Caroline A. Cobine, Salah A. Baker, Gerard P. Sergeant, Mark A. Hollywood, Keith D. Thornbury, Kenton M. Sanders

J Physiol. 2018 Apr 15; 596(8): 1433–1466. Published online 2018 Apr 15. doi: 10.1113/JP275719

PMCID:: PMC5899989

Abstract Article PDF–4.8M

Select item 583042513.

HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node

Yuko Kozasa, Noriyuki Nakashima, Masayuki Ito, Taisuke Ishikawa, Hiroki Kimoto, Kazuo Ushijima, Naomasa Makita, Makoto Takano

J Physiol. 2018 Mar 1; 596(5): 809–825. Published online 2018 Feb 6. doi: 10.1113/JP275303

PMCID:: PMC5830425

Abstract Article PDF–1.2M

Select item 541740514.

Triiodothyronine Promotes Cardiac Differentiation and Maturation of Embryonic Stem Cells via the Classical Genomic Pathway

Yee-Ki Lee, Kwong-Man Ng, Yau-Chi Chan, Wing-Hon Lai, Ka-Wing Au, Chung-Yee Jenny Ho, Lai-Yung Wong, Chu-Pak Lau, Hung-Fat Tse, Chung-Wah Siu

Mol Endocrinol. September 1, 2010; 24(9): 1728–1736. doi: 10.1210/me.2010-0032

PMCID:: PMC5417405

Abstract Article

Select item 534648515.

Ablation of the cardiac ryanodine receptor phospho-site Ser2808 does not alter the adrenergic response or the progression to heart failure in mice: Elimination of the genetic background as critical variable

Francisco J. Alvarado, Xi Chen, Héctor H. Valdivia

J Mol Cell Cardiol. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: J Mol Cell Cardiol. 2017 Feb; 103: 40–47. Published online 2017 Jan 6. doi: 10.1016/j.yjmcc.2017.01.001

PMCID:: PMC5346485

Abstract Article PDF–1.6M

Select item 529961816.

Extensive Ca²⁺ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca²⁺ hypersensitivity

Akira Uehara, Takashi Murayama, Midori Yasukochi, Michael Fill, Minoru Horie, Toru Okamoto, Yoshiharu Matsuura, Kiyoko Uehara, Takahiro Fujimoto, Takashi Sakurai, Nagomi Kurebayashi

J Gen Physiol. 2017 Feb; 149(2): 199–218. doi: 10.1085/jgp.201611624