PMC Links for Nucleotide (Select 1440017087) - PMC

Jonathan L. Chang, Sulggi A. Lee, Alexander C. Tsai, Nicholas Musinguzi, Conrad Muzoora, Bosco Bwana, Yap Boum, II, Jessica E. Haberer, Peter W. Hunt, Jeff Martin, David R. Bangsberg, Deanna L. Kroetz, Mark J. Siedner

AIDS Res Hum Retroviruses. 2018 Nov 1; 34(11): 982–992. Published online 2018 Nov 1. doi: 10.1089/aid.2018.0062

PMCID:: PMC6238612

Abstract Article PDF–434K

Select item 59795364.

Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog

Manish B. Shah, Qinghai Zhang, James R. Halpert

Int J Mol Sci. 2018 Apr; 19(4): 1025. Published online 2018 Mar 29. doi: 10.3390/ijms19041025

PMCID:: PMC5979536

Abstract Article PDF–21M

Select item 59142775.

Effects of Genetic Polymorphisms of CYP2B6 on the Pharmacokinetics of Bupropion and Hydroxybupropion in Healthy Chinese Subjects

Hui Ma, Wenping Zhang, Xiaoying Yang, Yuxin Zhang, Shijie Wei, Hao Zhang, Yanni Ma, Hongwan Dang

Med Sci Monit. 2018; 24: 2158–2163. Published online 2018 Apr 11. doi: 10.12659/MSM.909227

PMCID:: PMC5914277

Abstract Article PDF–386K

Select item 18012616.

A Genetic Polymorphism in Coumarin 7-Hydroxylation: Sequence of the Human CYP2A Gnes and Identification of Variant CYP2A6 Alleles

Pedro Fernandez-Salguero, Susan M. G. Hoffman, Suzanne Cholerton, Harvey Mohrenweiser, Hannu Raunio, Arja Rautio, Olavi Pelkonen, Jin-ding Huang, William E. Evans, Jeffrey R. Idle, Frank J. Gonzalez

Am J Hum Genet. 1995 Sep; 57(3): 651–660.

PMCID:: PMC1801261

Summary Page Browse PDF–1.6M

Select item 3368297.

A novel human cytochrome P450 gene (P450IIB): chromosomal localization and evidence for alternative splicing.

J S Miles, N K Spurr, A C Gough, T Jowett, A W McLaren, J D Brook, C R Wolf

Nucleic Acids Res. 1988 Jul 11; 16(13): 5783–5795. doi: 10.1093/nar/16.13.5783

PMCID:: PMC336829

Summary Page Browse PDF–1.3M

Select item 3349618.

Alternative splicing in the human cytochrome P450IIB6 gene generates a high level of aberrant messages.

J S Miles, A W McLaren, C R Wolf

Nucleic Acids Res. 1989 Oct 25; 17(20): 8241–8255. doi: 10.1093/nar/17.20.8241

PMCID:: PMC334961

Summary Page Browse PDF–1.4M

Select item 3302279.

Alternative splicing in the human cytochrome P450IIB6 gene: use of a cryptic exon within intron 3 and splice acceptor site within exon 4.

J S Miles, A W McLaren, F J Gonzalez, C R Wolf

Nucleic Acids Res. 1990 Jan 11; 18(1): 189. doi: 10.1093/nar/18.1.189

PMCID:: PMC330227

Summary Page Browse PDF–122K

Select item 630036610.

Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

Barbara Strojny, Ewa Sawosz, Marta Grodzik, Sławomir Jaworski, Jarosław Szczepaniak, Malwina Sosnowska, Mateusz Wierzbicki, Marta Kutwin, Sylwia Orlińska, André Chwalibog

Int J Nanomedicine. 2018; 13: 8561–8575. Published online 2018 Dec 13. doi: 10.2147/IJN.S188997

PMCID:: PMC6300366

Abstract Article PDF–5.0M

Select item 504594211.

Evaluation of a novel PXR‐knockout in HepaRG^™ cells

Beth Williamson, Mathias Lorbeer, Michael D. Mitchell, Timothy G. Brayman, Robert J. Riley

Pharmacol Res Perspect. 2016 Oct; 4(5): e00264. Published online 2016 Sep 21. doi: 10.1002/prp2.264

PMCID:: PMC5045942

Abstract Article PDF–820K

Select item 470377312.

An Expanded Analysis of Pharmacogenetics Determinants of Efavirenz Response that Includes 3′-UTR Single Nucleotide Polymorphisms among Black South African HIV/AIDS Patients

Marelize Swart, Jonathan Evans, Michelle Skelton, Sandra Castel, Lubbe Wiesner, Peter J. Smith, Collet Dandara

Front Genet. 2015; 6: 356. Published online 2016 Jan 7. doi: 10.3389/fgene.2015.00356

PMCID:: PMC4703773

Abstract Article PDF–2.4M

Select item 431913213.

Genetic variability of CYP2B6 polymorphisms in four southern Chinese populations

Bing-Ying Xu, Li-Ping Guo, Shui-Shan Lee, Qing-Ming Dong, Yi Tan, Hong Yao, Li-Hua Li, Che-Kit Lin, Hsiang-Fu Kung, Ming-Liang He

World J Gastroenterol. 2007 Apr 14; 13(14): 2100–2103. Published online 2007 Apr 14. doi: 10.3748/wjg.v13.i14.2100

PMCID:: PMC4319132

Abstract Article PDF–634K

Select item 430872814.

In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes

Anuradha Ramamoorthy, Todd C. Skaar

Drug Metab Lett. Author manuscript; available in PMC 2015 Jan 28.

Published in final edited form as: Drug Metab Lett. 2011 Apr; 5(2): 126–131. doi: 10.2174/187231211795305258

PMCID:: PMC4308728

Abstract Article PDF–466K

Select item 411480415.

Gene Expression Analysis Suggests Bone Development-Related Genes GDF5 and DIO2 Are Involved in the Development of Kashin-Beck Disease in Children Rather than Adults

Yan Wen, Feng Zhang, Chunyan Li, Shulan He, Wuhong Tan, Yanxia Lei, Qiang Zhang, Hanjie Yu, Jingjing Zheng, Xiong Guo

PLoS One. 2014; 9(7): e103618. Published online 2014 Jul 29. doi: 10.1371/journal.pone.0103618

PMCID:: PMC4114804

Abstract Article PDF–4.1M

Select item 409372116.

Expression of P450 and nuclear receptors in normal and end-stage Chinese livers

Hong Chen, Zhong-Yang Shen, Wang Xu, Tie-Yan Fan, Jun Li, Yuan-Fu Lu, Ming-Liang Cheng, Jie Liu

World J Gastroenterol. 2014 Jul 14; 20(26): 8681–8690. Published online 2014 Jul 14. doi: 10.3748/wjg.v20.i26.8681

PMCID:: PMC4093721

Abstract Article PDF–1.1M

Select item 404458317.

Genetic variation in the 3′-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance

Marelize Swart, Collet Dandara

Front Genet. 2014; 5: 167. Published online 2014 Jun 4. doi: 10.3389/fgene.2014.00167

PMCID:: PMC4044583

Abstract Article PDF–461K

Select item 368041318.

Distinct MicroRNAs Expression Profile in Primary Biliary Cirrhosis and Evaluation of miR 505-3p and miR197-3p as Novel Biomarkers

Masashi Ninomiya, Yasuteru Kondo, Ryo Funayama, Takeshi Nagashima, Takayuki Kogure, Eiji Kakazu, Osamu Kimura, Yoshiyuki Ueno, Keiko Nakayama, Tooru Shimosegawa

PLoS One. 2013; 8(6): e66086. Published online 2013 Jun 12. doi: 10.1371/journal.pone.0066086

PMCID:: PMC3680413

Abstract Article PDF–1.6M

Select item 365905919.

Anti-cancer effects of newly developed chemotherapeutic agent, glycoconjugated palladium (II) complex, against cisplatin-resistant gastric cancer cells

Mamoru Tanaka, Hiromi Kataoka, Shigenobu Yano, Hiromi Ohi, Keisuke Kawamoto, Takashi Shibahara, Tsutomu Mizoshita, Yoshinori Mori, Satoshi Tanida, Takeshi Kamiya, Takashi Joh

BMC Cancer. 2013; 13: 237. Published online 2013 May 14. doi: 10.1186/1471-2407-13-237

PMCID:: PMC3659059

Abstract Article PDF–646K

Select item 346699720.

A Single-Nucleotide Polymorphism in CYP2B6 Leads to >3-Fold Increases in Efavirenz Concentrations in Plasma and Hair Among HIV-Infected Women

Monica Gandhi, Ruth M. Greenblatt, Peter Bacchetti, Chengshi Jin, Yong Huang, Kathryn Anastos, Mardge Cohen, Jack A. DeHovitz, Gerald B. Sharp, Stephen J. Gange, Chenglong Liu, Susan C. Hanson, Bradley Aouizerat, for the Women's Interagency HIV Study

J Infect Dis. 2012 Nov 1; 206(9): 1453–1461. Published online 2012 Aug 20. doi: 10.1093/infdis/jis508