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Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Article PDF–1.2M

Select item 63676742.

Metastasis Suppressor NME1 Directly Activates Transcription of the ALDOC Gene in Melanoma Cells

NIDHI V. PAMIDIMUKKALA, MARY KATHRYN LEONARD, DEVIN SNYDER, JOSEPH R. MCCORKLE, DAVID M. KAETZEL

Anticancer Res. Author manuscript; available in PMC 2019 Feb 8.

Published in final edited form as: Anticancer Res. 2018 Nov; 38(11): 6059–6068. doi: 10.21873/anticanres.12956

PMCID:: PMC6367674

Article PDF–725K

Select item 55316113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Article PDF–2.7M

Select item 44412154.

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal

Cell. Author manuscript; available in PMC 2016 Apr 23.

Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013

PMCID:: PMC4441215

Article PDF–1.2M

Select item 16843395.

Evolutionary implications of the human aldolase-A, -B, -C, and -pseudogene chromosome locations.

D R Tolan, J Niclas, B D Bruce, R V Lebo

Am J Hum Genet. 1987 Nov; 41(5): 907–924.

PMCID:: PMC1684339

Article PDF–2.7M

Select item 3366726.

The complete nucleotide sequence of the gene coding for the human aldolase C.

P Buono, G Paolella, F P Mancini, P Izzo, F Salvatore

Nucleic Acids Res. 1988 May 25; 16(10): 4733. doi: 10.1093/nar/16.10.4733

PMCID:: PMC336672

Article PDF–168K

Select item 65943327.

Long Noncoding RNAs and Messenger RNAs Expression Profiles Potentially Regulated by ZBTB7A in Nasopharyngeal Carcinoma

Fei Liu, Jiazhang Wei, Yanrong Hao, Fengzhu Tang, Wei Jiao, Shenhong Qu, Ning He, Yonglin Cai, Jiao Lan, Yong Yang, Yongli Wang, Min Li, Jingjin Weng, Bing Li, Jinlong Lu, Xing Han

Biomed Res Int. 2019; 2019: 7246491. Published online 2019 Jun 11. doi: 10.1155/2019/7246491

PMCID:: PMC6594332

Article PDF–3.0M

Select item 62795948.

Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-regulated Genes

I Chae Ye, Elana J. Fertig, Josh W. DiGiacomo, Michael Considine, Inês Godet, Daniele M. Gilkes

Mol Cancer Res. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Mol Cancer Res. 2018 Dec; 16(12): 1889–1901. Published online 2018 Jul 23. doi: 10.1158/1541-7786.MCR-18-0345

PMCID:: PMC6279594

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Select item 57524819.

Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3

Stéphanie Buart, Stéphane Terry, Muhammad Z. Noman, Emilie Lanoy, Céline Boutros, Paul Fogel, Philippe Dessen, Guillaume Meurice, Yann Gaston-Mathé, Philippe Vielh, Séverine Roy, Emilie Routier, Virginie Marty, Sophie Ferlicot, Luc Legrès, Morad El. Bouchtaoui, Nyam Kamsu-Kom, Jane Muret, Eric Deutsch, Alexander Eggermont, Jean-Charles Soria, Caroline Robert, Salem Chouaib

Oncotarget. 2017 Dec 12; 8(65): 108786–108801. Published online 2017 Oct 30. doi: 10.18632/oncotarget.22150

PMCID:: PMC5752481

Article PDF–6.7M

Select item 523470410.

Anti-Müllerian hormone is produced heterogeneously in primate preantral follicles and is a potential biomarker for follicle growth and oocyte maturation in vitro

Jing Xu, Fuhua Xu, John H. Letaw, Byung S. Park, Robert P. Searles, Betsy M. Ferguson

J Assist Reprod Genet. 2016 Dec; 33(12): 1665–1675. Published online 2016 Sep 15. doi: 10.1007/s10815-016-0804-3

PMCID:: PMC5234704

Article PDF–920K

Select item 465166811.

LASP-1 – A nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex

Nichole Duvall-Noelle, Ayub Karwandyar, Ann Richmond, Dayanidhi Raman

Oncogene. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Oncogene. 2016 Mar 3; 35(9): 1122–1133. Published online 2015 May 18. doi: 10.1038/onc.2015.166

PMCID:: PMC4651668

Article PDF–1.4M

Select item 409468212.

Aldolase positively regulates of the canonical Wnt signaling pathway

Michal Caspi, Gili Perry, Nir Skalka, Shilhav Meisel, Anastasia Firsow, Maayan Amit, Rina Rosin-Arbesfeld

Mol Cancer. 2014; 13: 164. Published online 2014 Jul 4. doi: 10.1186/1476-4598-13-164

PMCID:: PMC4094682

Article PDF–2.2M

Select item 378204613.

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

Zhen Yang, Hiroshi Fujii, Shalini V. Mohan, Jorg J. Goronzy, Cornelia M. Weyand

J Exp Med. 2013 Sep 23; 210(10): 2119–2134. doi: 10.1084/jem.20130252

PMCID:: PMC3782046

Article PDF–2.8M

Select item 348722314.

Meta-Type Analysis of Dopaminergic Effects on Gene Expression in the Neuroendocrine Brain of Female Goldfish

Jason T. Popesku, Christopher J. Martyniuk, Vance L. Trudeau

Front Endocrinol (Lausanne) 2012; 3: 130. Published online 2012 Nov 2. doi: 10.3389/fendo.2012.00130

PMCID:: PMC3487223

Article PDF–2.2M

Select item 318970815.

Identification of Oxygen-Sensitive Transcriptional Programs in Human Embryonic Stem Cells

Suzanne D. Westfall, Shrikesh Sachdev, Padmalaya Das, Leonard B. Hearne, Mark Hannink, R. Michael Roberts, Toshihiko Ezashi

Stem Cells Dev. 2008 Oct; 17(5): 869–881. doi: 10.1089/scd.2007.0240

PMCID:: PMC3189708

Article PDF–2.5M

Select item 296264816.

Ets-1 Regulates Energy Metabolism in Cancer Cells

Meghan L. Verschoor, Leigh A. Wilson, Chris P. Verschoor, Gurmit Singh

PLoS One. 2010; 5(10): e13565. Published online 2010 Oct 22. doi: 10.1371/journal.pone.0013565

PMCID:: PMC2962648

Article PDF–524K

Select item 290858217.

A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

Paolo Fardin, Annalisa Barla, Sofia Mosci, Lorenzo Rosasco, Alessandro Verri, Rogier Versteeg, Huib N Caron, Jan J Molenaar, Ingrid Øra, Alessandra Eva, Maura Puppo, Luigi Varesio

Mol Cancer. 2010; 9: 185. Published online 2010 Jul 12. doi: 10.1186/1476-4598-9-185

PMCID:: PMC2908582

Article PDF–1.3M

Select item 290594518.

Identification of Multiple Hypoxia Signatures in Neuroblastoma Cell Lines by l₁-l₂ Regularization and Data Reduction

Paolo Fardin, Andrea Cornero, Annalisa Barla, Sofia Mosci, Massimo Acquaviva, Lorenzo Rosasco, Claudio Gambini, Alessandro Verri, Luigi Varesio

J Biomed Biotechnol. 2010; 2010: 878709. Published online 2010 Jun 28. doi: 10.1155/2010/878709

PMCID:: PMC2905945

Article PDF–1.0M

Select item 288217319.

Hypoxia inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

Hsin-Yu Fang, Russell Hughes, Craig Murdoch, Seth Coffelt, Subhra K. Biswas, Adrian L. Harris, Randall S. Johnson, Hongxia Z. Imityaz, M. Celeste Simon, Erik Fredlund, Florian Greten, Jordi Rius, Claire E. Lewis

Blood. Author manuscript; available in PMC 2010 Jun 8.

Published in final edited form as: Blood. 2009 Jul 23; 114(4): 844–859. Published online 2009 May 19. doi: 10.1182/blood-2008-12-195941

PMCID:: PMC2882173

Article PDF–2.5M

Select item 276875020.

The l₁-l₂regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines

Paolo Fardin, Annalisa Barla, Sofia Mosci, Lorenzo Rosasco, Alessandro Verri, Luigi Varesio

BMC Genomics. 2009; 10: 474. Published online 2009 Oct 15. doi: 10.1186/1471-2164-10-474

PMCID:: PMC2768750

Article PDF–1.6M

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