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Select item 63150211.

Pharmacological stimulation of NQO1 decreases NADPH levels and ameliorates acute pancreatitis in mice

AiHua Shen, Hyung-Jin Kim, Gi-Su Oh, Su-Bin Lee, SeungHoon Lee, Arpana Pandit, Dipendra Khadka, Subham Sharma, Seon Young Kim, Seong-Kyu Choe, Sei-Hoon Yang, Eun-Young Cho, Hyuk Shim, Raekil Park, Tae Hwan Kwak, Hong-Seob So

Cell Death Dis. 2019 Jan; 10(1): 5. Published online 2018 Dec 18. doi: 10.1038/s41419-018-1252-z

PMCID:: PMC6315021

Abstract Article PDF–1.7M

Select item 60809032.

NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation

Akihiro Kimura, Masayuki Kitajima, Kyoko Nishida, Satoshi Serada, Minoru Fujimoto, Tetsuji Naka, Yoshiaki Fujii-Kuriyama, Satoshi Sakamato, Takumi Ito, Hiroshi Handa, Takashi Tanaka, Akihiko Yoshimura, Harumi Suzuki

J Exp Med. 2018 Aug 6; 215(8): 2197–2209. doi: 10.1084/jem.20172024

PMCID:: PMC6080903

Abstract Article PDF–2.0M

Select item 60524033.

Overexpression of CYB5R3 and NQO1, two NAD⁺‐producing enzymes, mimics aspects of caloric restriction

Alberto Diaz‐Ruiz, Michael Lanasa, Joseph Garcia, Hector Mora, Frances Fan, Alejandro Martin‐Montalvo, Andrea Di Francesco, Miguel Calvo‐Rubio, Andrea Salvador‐Pascual, Miguel A. Aon, Kenneth W. Fishbein, Kevin J. Pearson, Jose Manuel Villalba, Placido Navas, Michel Bernier, Rafael de Cabo

Aging Cell. 2018 Aug; 17(4): e12767. Published online 2018 Apr 28. doi: 10.1111/acel.12767

PMCID:: PMC6052403

Abstract Article PDF–2.2M

Select item 59343824.

Glycine N-methyltransferase inhibits aristolochic acid nephropathy by increasing CYP3A44 and decreasing NQO1 expression in female mouse hepatocytes

Ming-Min Chang, Chang-Ni Lin, Cheng-Chieh Fang, Marcelo Chen, Peir-In Liang, Wei-Ming Li, Bi-Wen Yeh, Hung-Chi Cheng, Bu-Miin Huang, Wen-Jeng Wu, Yi-Ming Arthur Chen

Sci Rep. 2018; 8: 6960. Published online 2018 May 3. doi: 10.1038/s41598-018-22298-6

PMCID:: PMC5934382

Abstract Article PDF–16M

Select item 2979135.

Marked increases in hepatic NAD(P)H:oxidoreductase gene transcription and mRNA levels correlated with a mouse chromosome 7 deletion.

D D Petersen, F J Gonzalez, V Rapic, C A Kozak, J Y Lee, J E Jones, D W Nebert

Proc Natl Acad Sci U S A. 1989 Sep; 86(17): 6699–6703. doi: 10.1073/pnas.86.17.6699

PMCID:: PMC297913

Summary Page Browse PDF–1.2M

Select item 68233066.

The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro

Mateja Sborchia, Eric G. De Prez, Marie-Hélène Antoine, Lucie Bienfait, Radek Indra, Gabriel Valbuena, David H. Phillips, Joëlle L. Nortier, Marie Stiborová, Hector C. Keun, Volker M. Arlt

Arch Toxicol. 2019; 93(11): 3345–3366. Published online 2019 Oct 10. doi: 10.1007/s00204-019-02578-4

PMCID:: PMC6823306

Abstract Article PDF–2.9M

Select item 67339227.

Berberine Protects C17.2 Neural Stem Cells From Oxidative Damage Followed by Inducing Neuronal Differentiation

Jia-Wen Shou, Chun-Kai Cheung, Jian Gao, Wei-Wei Shi, Pang-Chui Shaw

Front Cell Neurosci. 2019; 13: 395. Published online 2019 Sep 3. doi: 10.3389/fncel.2019.00395

PMCID:: PMC6733922

Abstract Article PDF–11M

Select item 63873848.

Sulforaphane Protect Against Cadmium-Induced Oxidative Damage in mouse Leydigs Cells by Activating Nrf2/ARE Signaling Pathway

Shu-Hua Yang, Peng Li, Li-Hui Yu, Lin Li, Miao Long, Ming-Da Liu, Jian-Bin He

Int J Mol Sci. 2019 Feb; 20(3): 630. Published online 2019 Feb 1. doi: 10.3390/ijms20030630

PMCID:: PMC6387384

Abstract Article PDF–6.2M

Select item 61920659.

Acanthus ebracteatus leaf extract provides neuronal cell protection against oxidative stress injury induced by glutamate

Anchalee Prasansuklab, Tewin Tencomnao

BMC Complement Altern Med. 2018; 18: 278. Published online 2018 Oct 16. doi: 10.1186/s12906-018-2340-4

PMCID:: PMC6192065

Abstract Article PDF–3.9M

Select item 616721410.

Excess homocysteine upregulates the NRF2-antioxidant pathway in retinal Müller glial cells

Soumya Navneet, Xuezhi Cui, Jing. Zhao, Jing Wang, Navneet Ammal Kaidery, Bobby Thomas, Kathryn E. Bollinger, Yisang Yoon, Sylvia B. Smith

Exp Eye Res. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Exp Eye Res. 2019 Jan; 178: 228–237. Published online 2018 Mar 31. doi: 10.1016/j.exer.2018.03.022

PMCID:: PMC6167214

Abstract Article PDF–1.2M

Select item 610060511.

Protective Mechanism of Sulforaphane on Cadmium-Induced Sertoli Cell Injury in Mice Testis via Nrf2/ARE Signaling Pathway

Shu-Hua Yang, Li-Hui Yu, Lin Li, Yang Guo, Yi Zhang, Miao Long, Peng Li, Jian-Bin He

Molecules. 2018 Jul; 23(7): 1774. Published online 2018 Jul 19. doi: 10.3390/molecules23071774

PMCID:: PMC6100605

Abstract Article PDF–5.9M

Select item 601863512.

N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression

Gen Matsumoto, Tomonao Inobe, Takanori Amano, Kiyohito Murai, Nobuyuki Nukina, Nozomu Mori

Sci Rep. 2018; 8: 9585. Published online 2018 Jun 25. doi: 10.1038/s41598-018-27872-6

PMCID:: PMC6018635

Abstract Article PDF–4.5M

Select item 578498613.

In vitro antioxidant capacities of eight different kinds of apples and their effects on lipopolysaccharide-induced oxidative damage in mice

Shuang Guo, Yuehua Wang, Shurui Chou, Huijun Cui, Dongnan Li, Bin Li

PLoS One. 2018; 13(1): e0191762. Published online 2018 Jan 25. doi: 10.1371/journal.pone.0191762

PMCID:: PMC5784986

Abstract Article PDF–2.0M

Select item 577424614.

Nrf2 Deficiency Upregulates Intrarenal Angiotensin-Converting Enzyme-2 and Angiotensin 1-7 Receptor Expression and Attenuates Hypertension and Nephropathy in Diabetic Mice

Shuiling Zhao, Anindya Ghosh, Chao-Sheng Lo, Isabelle Chenier, James W. Scholey, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S. D. Chan

Endocrinology. 2018 Feb; 159(2): 836–852. Published online 2017 Dec 1. doi: 10.1210/en.2017-00752