PMC Links for Nucleotide (Select 1620863345) - PMC

Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 55316112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 54883973.

Hypoinsulinaemic, hypoketotic hypoglycaemia due to mosaic genetic activation of PI3-kinase

Sarah M Leiter, Victoria E R Parker, Alena Welters, Rachel Knox, Nuno Rocha, Graeme Clark, Felicity Payne, Luca Lotta, Julie Harris, Julio Guerrero-Fernández, Isabel González-Casado, Sixto García-Miñaur, Gema Gordo, Nick Wareham, Víctor Martínez-Glez, Michael Allison, Stephen O’Rahilly, Inês Barroso, Thomas Meissner, Susan Davies, Khalid Hussain, Karen Temple, Ana-Coral Barreda-Bonis, Sebastian Kummer, Robert K Semple

Eur J Endocrinol. 2017 Aug; 177(2): 175–186. Published online 2017 May 30. doi: 10.1530/EJE-17-0132

PMCID:: PMC5488397

Abstract Article PDF–10M

Select item 53871334.

The regulation of tumor‐suppressive microRNA, miR‐126, in chronic lymphocytic leukemia

Daphne Guinn, Amy Lehman, Catherine Fabian, Lianbo Yu, Kami Maddocks, Leslie A. Andritsos, Jeffrey A. Jones, Joseph M. Flynn, Samantha M. Jaglowski, Jennifer A. Woyach, John C. Byrd, Amy J. Johnson

Cancer Med. 2017 Apr; 6(4): 778–787. Published online 2017 Mar 15. doi: 10.1002/cam4.996

PMCID:: PMC5387133

Abstract Article PDF–396K

Select item 21914245.

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

J Exp Med. 1994 Mar 1; 179(3): 1071–1076. doi: 10.1084/jem.179.3.1071

PMCID:: PMC2191424

Summary PDF–886K

Select item 11320246.

Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system.

I Gout, R Dhand, G Panayotou, M J Fry, I Hiles, M Otsu, M D Waterfield

Biochem J. 1992 Dec 1; 288(Pt 2): 395–405. doi: 10.1042/bj2880395

PMCID:: PMC1132024

Summary Page Browse PDF–4.1M

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