PMC Links for Nucleotide (Select 1653961841) - PMC

Select item 67544461.

Regulation of the endosomal SNX27-retromer by OTULIN

Aurelia Stangl, Paul R. Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison, Annalisa Schaub, Kerstin Kutzner, Kirstin Keusekotten, Paul T. Pfluger, Farid El Oualid, Benedikt M. Kessler, David Komander, Daniel Krappmann

Nat Commun. 2019; 10: 4320. Published online 2019 Sep 20. doi: 10.1038/s41467-019-12309-z

PMCID:: PMC6754446

Abstract Article PDF–6.0M

Select item 50187682.

Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease

Qing Zhou, Xiaomin Yu, Erkan Demirkaya, Natalie Deuitch, Deborah Stone, Wanxia Li Tsai, Hye Sun Kuehn, Hongying Wang, Dan Yang, Yong Hwan Park, Amanda K. Ombrello, Mary Blake, Tina Romeo, Elaine F. Remmers, Jae Jin Chae, James C. Mullikin, Ferhat Güzel, Joshua D. Milner, Manfred Boehm, Sergio D. Rosenzweig, Massimo Gadina, Steven B. Welch, Seza Özen, Rezan Topaloglu, Mario Abinun, Daniel L. Kastner, Ivona Aksentijevich

Proc Natl Acad Sci U S A. 2016 Sep 6; 113(36): 10127–10132. Published online 2016 Aug 24. doi: 10.1073/pnas.1612594113

PMCID:: PMC5018768

Abstract Article PDF–1.2M

Select item 50022693.

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

Rune Busk Damgaard, Jennifer A. Walker, Paola Marco-Casanova, Neil V. Morgan, Hannah L. Titheradge, Paul R. Elliott, Duncan McHale, Eamonn R. Maher, Andrew N.J. McKenzie, David Komander

Cell. 2016 Aug 25; 166(5): 1215–1230.e20. doi: 10.1016/j.cell.2016.07.019

PMCID:: PMC5002269

Abstract Article

Select item 49319164.

The linear ubiquitin-specific deubiquitinase Gumby/Fam105b regulates angiogenesis

Elena Rivkin, Stephanie M. Almeida, Derek F. Ceccarelli, Yu-Chi Juang, Teresa A. MacLean, Tharan Srikumar, Hao Huang, Wade H. Dunham, Ryutaro Fukumura, Gang Xie, Yoichi Gondo, Brian Raught, Anne-Claude Gingras, Frank Sicheri, Sabine P. Cordes

Nature. Author manuscript; available in PMC 2016 Jul 4.

Published in final edited form as: Nature. 2013 Jun 20; 498(7454): 318–324. Published online 2013 May 24. doi: 10.1038/nature12296

PMCID:: PMC4931916

Abstract Article PDF–1.9M

Select item 48199075.

CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling

Matous Hrdinka, Berthe Katrine Fiil, Mattia Zucca, Derek Leske, Katrin Bagola, Monica Yabal, Paul R. Elliott, Rune Busk Damgaard, David Komander, Philipp J. Jost, Mads Gyrd-Hansen

Cell Rep. 2016 Mar 29; 14(12): 2846–2858. Published online 2016 Mar 17. doi: 10.1016/j.celrep.2016.02.062

PMCID:: PMC4819907

Abstract Article PDF–3.6M

Select item 41944276.

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling

Berthe Katrine Fiil, Rune Busk Damgaard, Sebastian Alexander Wagner, Kirstin Keusekotten, Melanie Fritsch, Simon Bekker-Jensen, Niels Mailand, Chunaram Choudhary, David Komander, Mads Gyrd-Hansen

Mol Cell. Author manuscript; available in PMC 2014 Oct 13.

Published in final edited form as: Mol Cell. 2013 Jun 27; 50(6): 818–830. doi: 10.1016/j.molcel.2013.06.004

PMCID:: PMC4194427

Abstract Article PDF–1.8M

Select item 37052087.

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

Tycho E.T. Mevissen, Manuela K. Hospenthal, Paul P. Geurink, Paul R. Elliott, Masato Akutsu, Nadia Arnaudo, Reggy Ekkebus, Yogesh Kulathu, Tobias Wauer, Farid El Oualid, Stefan M.V. Freund, Huib Ovaa, David Komander

Cell. 2013 Jul 3; 154(1): 169–184. doi: 10.1016/j.cell.2013.05.046

PMCID:: PMC3705208

Abstract Article

Select item 36904818.

OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin

Kirstin Keusekotten, Paul Ronald Elliott, Laura Glockner, Berthe Katrine Fiil, Rune Busk Damgaard, Yogesh Kulathu, Tobias Wauer, Manuela Kathrin Hospenthal, Mads Gyrd-Hansen, Daniel Krappmann, Kay Hofmann, David Komander

Cell. 2013 Jun 6; 153(6): 1312–1326. doi: 10.1016/j.cell.2013.05.014

PMCID:: PMC3690481

Abstract Article

Select item 27854739.

CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells

Silvia Deaglio, Semra Aydin, Maurizia Mello Grand, Tiziana Vaisitti, Luciana Bergui, Giovanni D’Arena, Giovanna Chiorino, Fabio Malavasi

Mol Med. 2010 Mar-Apr; 16(3-4): 87–91. Published online 2009 Nov 28. doi: 10.2119/molmed.2009.00146

PMCID:: PMC2785473

Abstract Article PDF–245K

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