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Links from Nucleotide

Items: 7

1.
5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation
Juan Wang, Liang Peng, Ruihua Zhang, Zihan Zheng, Chun Chen, Ka Lung Cheung, Miao Cui, Guanglin Bian, Feihong Xu, David Chiang, Yuan Hu, Ye Chen, Geming Lu, Jianjun Yang, Hui Zhang, Jianfei Yang, Hongfa Zhu, Shu-hsia Chen, Kebin Liu, Ming-Ming Zhou, Andrew G. Sikora, Liwu Li, Bo Jiang, Huabao Xiong
Oncotarget. 2016 Apr 12; 7(15): 19312–19326. Published online 2016 Mar 24. doi: 10.18632/oncotarget.8344
PMCID:
PMC4991385
AbstractArticlePDF–1.7M
2.
Crystal Structure of Mouse Thymidylate Synthase in Tertiary Complex with dUMP and Raltitrexed Reveals N-Terminus Architecture and Two Different Active Site Conformations
Anna Dowierciał, Piotr Wilk, Wojciech Rypniewski, Wojciech Rode, Adam Jarmuła
Biomed Res Int. 2014; 2014: 945803. Published online 2014 Jun 3. doi: 10.1155/2014/945803
PMCID:
PMC4065713
AbstractArticlePDF–6.6M
3.
A Retinoblastoma Allele That Is Mutated at Its Common E2F Interaction Site Inhibits Cell Proliferation in Gene-Targeted Mice
Matthew J. Cecchini, Michael J. Thwaites, Srikanth Talluri, James I. MacDonald, Daniel T. Passos, Jean-Leon Chong, Paul Cantalupo, Paul M. Stafford, M. Teresa Sáenz-Robles, Sarah M. Francis, James M. Pipas, Gustavo Leone, Ian Welch, Frederick A. Dick
Mol Cell Biol. 2014 Jun; 34(11): 2029–2045. doi: 10.1128/MCB.01589-13
PMCID:
PMC4019062
AbstractArticlePDF–3.4M
4.
Nuclear Localization of de Novo Thymidylate Biosynthesis Pathway Is Required to Prevent Uracil Accumulation in DNA
Amanda J. MacFarlane, Donald D. Anderson, Per Flodby, Cheryll A. Perry, Robert H. Allen, Sally P. Stabler, Patrick J. Stover
J Biol Chem. 2011 Dec 23; 286(51): 44015–44022. Published online 2011 Nov 4. doi: 10.1074/jbc.M111.307629
PMCID:
PMC3243516
AbstractArticlePDF–1.2M
5.
Mouse thymidylate synthase messenger RNA lacks a 3' untranslated region.
C H Jenh, T L Deng, D W Li, J DeWille, L F Johnson
Proc Natl Acad Sci U S A. 1986 Nov; 83(22): 8482–8486. doi: 10.1073/pnas.83.22.8482
PMCID:
PMC386954
SummaryPage BrowsePDF–1.0M
6.
Thymidylate synthase gene expression is stimulated by some (but not all) introns.
T L Deng, Y Li, L F Johnson
Nucleic Acids Res. 1989 Jan 25; 17(2): 645–658. doi: 10.1093/nar/17.2.645
PMCID:
PMC331609
SummaryPage BrowsePDF–1.1M
7.
Polyadenylylation signal of the mouse thymidylate synthase gene was created by insertion of an L1 repetitive element downstream of the open reading frame.
C J Harendza, L F Johnson
Proc Natl Acad Sci U S A. 1990 Apr; 87(7): 2531–2535. doi: 10.1073/pnas.87.7.2531
PMCID:
PMC53723
SummaryPage BrowsePDF–1.3M

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