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Select item 65869061.

CD46 facilitates entry and dissemination of human cytomegalovirus

Kathryn R. Stein, Thomas J. Gardner, Rosmel E. Hernandez, Thomas A. Kraus, James A. Duty, Iban Ubarretxena-Belandia, Thomas M. Moran, Domenico Tortorella

Nat Commun. 2019; 10: 2699. Published online 2019 Jun 20. doi: 10.1038/s41467-019-10587-1

PMCID:: PMC6586906

Abstract Article PDF–3.1M

Select item 61801322.

Complement receptor CD46 co-stimulates optimal human CD8⁺ T cell effector function via fatty acid metabolism

Giuseppina Arbore, Erin E. West, Jubayer Rahman, Gaelle Le Friec, Nathalie Niyonzima, Mehdi Pirooznia, Ilker Tunc, Polychronis Pavlidis, Nicholas Powell, Yuesheng Li, Poching Liu, Aude Servais, Lionel Couzi, Veronique Fremeaux-Bacchi, Leo Placais, Alastair Ferraro, Patrick R. Walsh, David Kavanagh, Behdad Afzali, Paul Lavender, Helen J. Lachmann, Claudia Kemper

Nat Commun. 2018; 9: 4186. Published online 2018 Oct 10. doi: 10.1038/s41467-018-06706-z

PMCID:: PMC6180132

Abstract Article PDF–2.0M

Select item 21889573.

Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins

J Exp Med. 1988 Jul 1; 168(1): 181–194. doi: 10.1084/jem.168.1.181

PMCID:: PMC2188957

Summary PDF–892K

Select item 21188784.

Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype

J Exp Med. 1991 Jul 1; 174(1): 93–102. doi: 10.1084/jem.174.1.93

PMCID:: PMC2118878

Summary PDF–1.4M

Select item 2407285.

Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome

Anna Richards, Elizabeth J. Kemp, M. Kathryn Liszewski, Judith A. Goodship, Anne K. Lampe, Ronny Decorte, M. Hamza Müslümanogğlu, Salih Kavukcu, Guido Filler, Yves Pirson, Leana S. Wen, John P. Atkinson, Timothy H. J. Goodship

Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22): 12966–12971. Published online 2003 Oct 17. doi: 10.1073/pnas.2135497100

PMCID:: PMC240728

Abstract Article PDF–503K

Select item 68303306.

Mesenchymal Stem Cells in the Adult Human Liver: Hype or Hope?

Irina V. Kholodenko, Leonid K. Kurbatov, Roman V. Kholodenko, Garik V. Manukyan, Konstantin N. Yarygin

Cells. 2019 Oct; 8(10): 1127. Published online 2019 Sep 22. doi: 10.3390/cells8101127

PMCID:: PMC6830330

Abstract Article PDF–1.7M

Select item 63248407.

Statistical validation of rare complement variants provides insights on the molecular basis of atypical haemolytic uraemic syndrome and C3 glomerulopathy

Amy J. Osborne, Matteo Breno, Nicolo Ghiringhelli Borsa, Fengxiao Bu, Véronique Frémeaux-Bacchi, Daniel P. Gale, Lambertus P. van den Heuvel, David Kavanagh, Marina Noris, Sheila Pinto, Pavithra M. Rallapalli, Giuseppe Remuzzi, Santiago Rodríguez de Cordoba, Angela Ruiz, Richard J. H. Smith, Paula Vieira-Martins, Elena Volokhina, Valerie Wilson, Timothy H. J. Goodship, Stephen J. Perkins

J Immunol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: J Immunol. 2018 Apr 1; 200(7): 2464–2478. Published online 2018 Mar 2. doi: 10.4049/jimmunol.1701695

PMCID:: PMC6324840

Abstract Article PDF–2.6M

Select item 63234178.

Interpretation of Genomic Sequencing Results in Healthy and Ill Newborns: Results from the BabySeq Project

Ozge Ceyhan-Birsoy, Jaclyn B. Murry, Kalotina Machini, Matthew S. Lebo, Timothy W. Yu, Shawn Fayer, Casie A. Genetti, Talia S. Schwartz, Pankaj B. Agrawal, Richard B. Parad, Ingrid A. Holm, Amy L. McGuire, Robert C. Green, Heidi L. Rehm, Alan H. Beggs, The BabySeq Project Team

Am J Hum Genet. 2019 Jan 3; 104(1): 76–93. Published online 2019 Jan 3. doi: 10.1016/j.ajhg.2018.11.016

PMCID:: PMC6323417

Abstract Article PDF–412K

Select item 61020739.

4-Hydroxy-7-oxo-5-heptenoic Acid (HOHA) Lactone is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells

Mikhail Linetsky, Karina S. Bondelid, Sofiya Losovskiy, Vadym Gabyak, Mario J. Rullo, Thomas I. Stiadle, Vasu Munjapara, Priyali Saxena, Duoming Ma, Yu-Shiuan Cheng, Andrew M. Howes, Emeka Udeigwe, Robert G. Salomon

Chem Res Toxicol. Author manuscript; available in PMC 2019 Aug 20.

Published in final edited form as: Chem Res Toxicol. 2018 Aug 20; 31(8): 666–679. Published online 2018 Jul 9. doi: 10.1021/acs.chemrestox.8b00028

PMCID:: PMC6102073

Abstract Article PDF–1.7M

Select item 543342910.

Genome-Wide Associations of CD46 and IFI44L Genetic Variants with Neutralizing Antibody Response to Measles Vaccine

Iana H. Haralambieva, Inna G. Ovsyannikova, Richard B. Kennedy, Beth R. Larrabee, Michael T. Zimmermann, Diane E. Grill, Daniel J. Schaid, Gregory A. Poland

Hum Genet. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Hum Genet. 2017 Apr; 136(4): 421–435. Published online 2017 Mar 13. doi: 10.1007/s00439-017-1768-9

PMCID:: PMC5433429

Abstract Article PDF–1.2M

Select item 521723811.

Turkish pediatric atypical hemolytic uremic syndrome registry: initial analysis of 146 patients

Nesrin Besbas, Bora Gulhan, Oguz Soylemezoglu, Z. Birsin Ozcakar, Emine Korkmaz, Mutlu Hayran, Fatih Ozaltin

BMC Nephrol. 2017; 18: 6. Published online 2017 Jan 5. doi: 10.1186/s12882-016-0420-6

PMCID:: PMC5217238

Abstract Article PDF–451K

Select item 520386012.

Serological and genetic complement alterations in infection-induced and complement-mediated hemolytic uremic syndrome

Dineke Westra, Elena B. Volokhina, Renate G. van der Molen, Thea J. A. M. van der Velden, Annelies Jeronimus-Klaasen, Joop Goertz, Valentina Gracchi, Eiske M. Dorresteijn, Antonia H. M. Bouts, Mandy G. Keijzer-Veen, Joanna A. E. van Wijk, Jaap A. Bakker, Anja Roos, Lambert P. van den Heuvel, Nicole C. A. J. van de Kar

Pediatr Nephrol. 2017; 32(2): 297–309. Published online 2016 Oct 7. doi: 10.1007/s00467-016-3496-0

PMCID:: PMC5203860

Abstract Article PDF–554K

Select item 497237013.

Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids

Sonali Nashine, Marilyn Chwa, Mina Kazemian, Kunal Thaker, Stephanie Lu, Anthony Nesburn, Baruch D. Kuppermann, M. Cristina Kenney

PLoS One. 2016; 11(8): e0159828. Published online 2016 Aug 3. doi: 10.1371/journal.pone.0159828

PMCID:: PMC4972370

Abstract Article PDF–1.9M

Select item 434218314.

Hsa-microRNA-181a is a regulator of a number of cancer genes and a biomarker for endometrial carcinoma in patients: a bioinformatic and clinical study and the therapeutic implication

Shuming He, Shumei Zeng, Zhi-Wei Zhou, Zhi-Xu He, Shu-Feng Zhou

Drug Des Devel Ther. 2015; 9: 1103–1175. Published online 2015 Feb 18. doi: 10.2147/DDDT.S73551

PMCID:: PMC4342183

Abstract Article PDF–16M

Select item 420686315.

New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3

Elizabeth Rodriguez, Pavithra M. Rallapalli, Amy J. Osborne, Stephen J. Perkins

Biosci Rep. 2014; 34(5): e00146. Prepublished online 2014 Sep 4. Published online 2014 Oct 22. doi: 10.1042/BSR20140117

PMCID:: PMC4206863

Abstract Article PDF–1.7M

Select item 375034116.

Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome

Shuju Feng, Stephen J. Eyler, Yuzhou Zhang, Tara Maga, Carla M. Nester, Michael H. Kroll, Richard J. Smith, Vahid Afshar-Kharghan

Blood. 2013 Aug 22; 122(8): 1487–1493. Prepublished online 2013 Jul 11. doi: 10.1182/blood-2013-03-492421

PMCID:: PMC3750341

Abstract Article

Select item 346961817.

Molecular inflammation and adipose tissue matrix remodeling precede physiological adaptations to pregnancy

Veronica Resi, Subhabrata Basu, Maricela Haghiac, Larraine Presley, Judi Minium, Bram Kaufman, Steven Bernard, Patrick Catalano, Sylvie Hauguel-de Mouzon

Am J Physiol Endocrinol Metab. 2012 Oct 1; 303(7): E832–E840. Published online 2012 Jul 17. doi: 10.1152/ajpendo.00002.2012

PMCID:: PMC3469618

Abstract Article

Select item 341226418.

Lessons of leprosy: The emergence of TH17 cytokines during type II reactions (ENL) is teaching us about T-cell plasticity

Frank Martiniuk, Jerome Giovinazzo, Ainah U. Tan, Rozana Shahidullah, Patrick Haslett, Gilla Kaplan, William R. Levis

J Drugs Dermatol. Author manuscript; available in PMC 2012 Aug 6.

Published in final edited form as: J Drugs Dermatol. 2012 May; 11(5): 626–630.

PMCID:: PMC3412264

Abstract Article PDF–391K

Select item 336988919.

A novel in vitro three-dimensional retinoblastoma model for evaluating chemotherapeutic drugs

Moutushy Mitra, Chandana Mohanty, Anju Harilal, Uma K. Maheswari, Sanjeeb Kumar Sahoo, Subramanian Krishnakumar

Mol Vis. 2012; 18: 1361–1378. Published online 2012 May 31.

PMCID:: PMC3369889

Abstract Article PDF–2.4M

Select item 316198920.

Tumor Cell Marker PVRL4 (Nectin 4) Is an Epithelial Cell Receptor for Measles Virus

Ryan S. Noyce, Daniel G. Bondre, Michael N. Ha, Liang-Tzung Lin, Gary Sisson, Ming-Sound Tsao, Christopher D. Richardson

PLoS Pathog. 2011 Aug; 7(8): e1002240. Published online 2011 Aug 25. doi: 10.1371/journal.ppat.1002240

PMCID:: PMC3161989

Abstract Article PDF–14M

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