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Items: 1 to 20 of 54

1.
Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus
Steven S. Good, Adel Moussa, Xiao-Jian Zhou, Keith Pietropaolo, Jean-Pierre Sommadossi
PLoS One. 2020; 15(1): e0227104. Published online 2020 Jan 8. doi: 10.1371/journal.pone.0227104
PMCID:
PMC6949113
AbstractArticlePDF–2.2M
2.
The Investigation of Drug Resistance Substitutions in NS3 Protease Sequence of Hepatitis C Virus from Non-Responder Patients
Nargess Nejabat, Seyed Younes Hosseini, Jamal Sarvari, Ali Akbar Gorzin, Mohammad Reza Fattahi, Mohammad Rasoolian
Asian Pac J Cancer Prev. 2019; 20(8): 2311–2317. doi: 10.31557/APJCP.2019.20.8.2311
PMCID:
PMC6852801
AbstractArticlePDF–800K
3.
Circulating CXCR3+ Tfh cells positively correlate with neutralizing antibody responses in HCV-infected patients
Jian Zhang, Wenpei Liu, Bo Wen, Ting Xie, Ping Tang, Yabin Hu, Liyan Huang, Kun Jin, Ping Zhang, Ziyan Liu, Ling Niu, Xiaowang Qu
Sci Rep. 2019; 9: 10090. Published online 2019 Jul 12. doi: 10.1038/s41598-019-46533-w
PMCID:
PMC6626020
AbstractArticlePDF–3.5M
4.
Core encoding sequences of Hepatitis C virus in Ghanaian blood donors are predominantly mosaics of different genotype 2 strains and cannot distinguish subtypes
Nicholas Israel Nii-Trebi, Charles Addoquaye Brown, Yaa Difie Osei, William Kwabena Ampofo, Alexander Kwadwo Nyarko
BMC Infect Dis. 2019; 19: 533. Published online 2019 Jun 17. doi: 10.1186/s12879-019-4155-4
PMCID:
PMC6580569
AbstractArticlePDF–1.5M
5.
In Vitro Susceptibility of Hepatitis C Virus Genotype 1 through 6 Clinical Isolates to the Pangenotypic NS3/4A Inhibitor Voxilaprevir
Bin Han, Bandita Parhy, Julia Lu, Eric Zhou, David Hsieh, Gregory Camus, Ross Martin, Evguenia S. Svarovskaia, Hongmei Mo, Hadas Dvory-Sobol
J Clin Microbiol. 2019 Apr; 57(4): e01844-18. Prepublished online 2019 Feb 6. Published online 2019 Mar 28. doi: 10.1128/JCM.01844-18
Correction in:
J Clin Microbiol. 2020 Jul; 58(7): e00857-20.
PMCID:
PMC6440772
AbstractArticlePDF–1.4M
6.
Infrequent Development of Resistance in Genotype 1–6 Hepatitis C Virus–Infected Subjects Treated With Sofosbuvir in Phase 2 and 3 Clinical Trials
Evguenia S. Svarovskaia, Hadas Dvory-Sobol, Neil Parkin, Christy Hebner, Viktoria Gontcharova, Ross Martin, Wen Ouyang, Bin Han, Simin Xu, Karin Ku, Sophia Chiu, Edward Gane, Ira M. Jacobson, David R. Nelson, Eric Lawitz, David L. Wyles, Neby Bekele, Diana Brainard, William T. Symonds, John G. McHutchison, Michael D. Miller, Hongmei Mo
Clin Infect Dis. 2014 Dec 15; 59(12): 1666–1674. Published online 2014 Sep 28. doi: 10.1093/cid/ciu697
PMCID:
PMC6433438
AbstractArticlePDF–220K
7.
Analysis of resistance-associated substitutions in acute hepatitis C virus infection by deep sequencing across six genotypes and three continents.
Auda A. Eltahla, Chaturaka Rodrigo, Brigid Betz-Stablein, Jason Grebely, Tanya Applegate, Fabio Luciani, Janke Schinkel, Gregory J. Dore, Kimberly Page, Julie Bruneau, Meghan D. Morris, Andrea L. Cox, Arthur Y. Kim, Naglaa H. Shoukry, Georg M. Lauer, Lisa Maher, Margaret Hellard, Maria Prins, Andrew R. Lloyd, Rowena A. Bull
J Viral Hepat. Author manuscript; available in PMC 2019 Mar 17.
Published in final edited form as: J Viral Hepat. 2017 Jan; 24(1): 37–42. Published online 2016 Sep 25. doi: 10.1111/jvh.12615
PMCID:
PMC6421067
AbstractArticlePDF–1.0M
8.
NS2 proteases from hepatitis C virus and related hepaciviruses share composite active sites and previously unrecognized intrinsic proteolytic activities
Célia Boukadida, Matthieu Fritz, Brigitte Blumen, Marie-Laure Fogeron, François Penin, Annette Martin
PLoS Pathog. 2018 Feb; 14(2): e1006863. Published online 2018 Feb 7. doi: 10.1371/journal.ppat.1006863
PMCID:
PMC5819835
AbstractArticlePDF–28M
9.
Blocking Zika virus vertical transmission
Pinar Mesci, Angela Macia, Spencer M. Moore, Sergey A. Shiryaev, Antonella Pinto, Chun-Teng Huang, Leon Tejwani, Isabella R. Fernandes, Nicole A. Suarez, Matthew J. Kolar, Sandro Montefusco, Scott C. Rosenberg, Roberto H. Herai, Fernanda R. Cugola, Fabiele B. Russo, Nicholas Sheets, Alan Saghatelian, Sujan Shresta, Jeremiah D. Momper, Jair L. Siqueira-Neto, Kevin D. Corbett, Patricia C. B. Beltrão-Braga, Alexey V. Terskikh, Alysson R. Muotri
Sci Rep. 2018; 8: 1218. Published online 2018 Jan 19. doi: 10.1038/s41598-018-19526-4
Correction in:
Sci Rep. 2018; 8: 8794.
PMCID:
PMC5775359
AbstractArticlePDF–2.4M
10.
In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir
Teresa I. Ng, Rakesh Tripathi, Thomas Reisch, Liangjun Lu, Timothy Middleton, Todd A. Hopkins, Ron Pithawalla, Michelle Irvin, Tatyana Dekhtyar, Preethi Krishnan, Gretja Schnell, Jill Beyer, Keith F. McDaniel, Jun Ma, Guoqiang Wang, Li-Juan Jiang, Yat Sun Or, Dale Kempf, Tami Pilot-Matias, Christine Collins
Antimicrob Agents Chemother. 2018 Jan; 62(1): e01620-17. Prepublished online 2017 Oct 30. Published online 2017 Dec 21. doi: 10.1128/AAC.01620-17
PMCID:
PMC5740381
AbstractArticlePDF–455K
11.
A Single-step Multiplex Quantitative Real Time Polymerase Chain Reaction Assay for Hepatitis C Virus Genotypes
Akanksha Singh, Dhananjay Singh Mankotia, Mohammad Irshad
J Transl Int Med. 2017 Mar; 5(1): 34–42. Published online 2017 Mar 31. doi: 10.1515/jtim-2017-0010
PMCID:
PMC5490960
AbstractArticlePDF–1.4M
12.
Impact of host responses on control of hepatitis C virus infection in Chinese blood donors
Tingting Li, Zixuan Chen, Jinfeng Zeng, Jingang Zhang, Wenjing Wang, Ling Zhang, Xin Zheng, Lifang Shuai, Paul Klenerman, Jean-Pierre Allain, Chengyao Li
Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 Jul 8.
Published in final edited form as: Biochem Biophys Res Commun. 2011 Nov 25; 415(3): 503–508. Published online 2011 Oct 29. doi: 10.1016/j.bbrc.2011.10.102
PMCID:
PMC4937991
AbstractArticlePDF–826K
13.
The Combination of Grazoprevir, a Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor, and Elbasvir, an HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV Genotype 1a Replicons
Frederick C. Lahser, Karin Bystol, Stephanie Curry, Patricia McMonagle, Ellen Xia, Paul Ingravallo, Robert Chase, Rong Liu, Todd Black, Daria Hazuda, Anita Y. M. Howe, Ernest Asante-Appiah
Antimicrob Agents Chemother. 2016 May; 60(5): 2954–2964. Prepublished online 2016 Feb 29. Published online 2016 Apr 22. doi: 10.1128/AAC.00051-16
PMCID:
PMC4862497
AbstractArticlePDF–1.0M
14.
Decreasing Hepatitis C Virus Infection in Thailand in the Past Decade: Evidence from the 2014 National Survey
Rujipat Wasitthankasem, Nawarat Posuwan, Preeyaporn Vichaiwattana, Apiradee Theamboonlers, Sirapa Klinfueng, Viboonsak Vuthitanachot, Napha Thanetkongtong, Siriporn Saelao, Monthana Foonoi, Apinya Fakthongyoo, Jamorn Makaroon, Klaita Srisingh, Duangporn Asawarachun, Somchai Owatanapanich, Norra Wutthiratkowit, Kraisorn Tohtubtiang, Pornsak Yoocharoen, Sompong Vongpunsawad, Yong Poovorawan
PLoS One. 2016; 11(2): e0149362. Published online 2016 Feb 12. doi: 10.1371/journal.pone.0149362
Correction in:
PLoS One. 2016; 11(5): e0152451.
PMCID:
PMC4752320
AbstractArticlePDF–2.1M
15.
Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A
Margarita Zayas, Gang Long, Vanesa Madan, Ralf Bartenschlager
PLoS Pathog. 2016 Jan; 12(1): e1005376. Published online 2016 Jan 4. doi: 10.1371/journal.ppat.1005376
PMCID:
PMC4699712
AbstractArticlePDF–1.9M
16.
Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Intergenotypic Variable Region
Yousef Alhammad, Jun Gu, Irene Boo, David Harrison, Kathleen McCaffrey, Patricia T. Vietheer, Stirling Edwards, Charles Quinn, Fásseli Coulibaly, Pantelis Poumbourios, Heidi E. Drummer
J Virol. 2015 Dec 15; 89(24): 12245–12261. Published online 2015 Sep 16. doi: 10.1128/JVI.02070-15
PMCID:
PMC4665232
AbstractArticlePDF–7.1M
17.
Analysis of Naturally Occurring Resistant Mutations to Hepatitis C Virus NS3 Protease Inhibitors: A Preliminary Study in South of Iran
Mozhgan Afrasiabi, Seyed Younes Hosseini, Ramin Yaghobi, Mohammad-Reza Fattahi, Maryam Ardebili, Mahboobeh Khodadad
Jundishapur J Microbiol. 2015 Oct; 8(10): e24965. Published online 2015 Oct 29. doi: 10.5812/jjm.24965
PMCID:
PMC4644313
AbstractArticlePDF–1.0M
18.
Evidence of Distinct Populations of Hepatitis C Virus in the Liver and Plasma of Patients Co-Infected With HIV and HCV
Jason T. Blackard, Gang Ma, Satarupa Sengupta, Christina M. Martin, Eleanor A. Powell, M. Tarek Shata, Kenneth E. Sherman
J Med Virol. Author manuscript; available in PMC 2015 Sep 8.
Published in final edited form as: J Med Virol. 2014 Aug; 86(8): 1332–1341. Published online 2014 Apr 30. doi: 10.1002/jmv.23968
PMCID:
PMC4562016
AbstractArticlePDF–464K
19.
Encoded Library Technology Screening of Hepatitis C Virus NS4B Yields a Small-Molecule Compound Series with In Vitro Replicon Activity
Christopher Arico-Muendel, Zhengrong Zhu, Hamilton Dickson, Derek Parks, Jesse Keicher, Jianghe Deng, Leah Aquilani, Frank Coppo, Todd Graybill, Kenneth Lind, Andrew Peat, Michael Thomson
Antimicrob Agents Chemother. 2015 Jun; 59(6): 3450–3459. Prepublished online 2015 Mar 30. Published online 2015 May 14. doi: 10.1128/AAC.00070-15
PMCID:
PMC4432136
AbstractArticlePDF–1.6M
20.
Genotypic Distribution of Hepatitis C Virus in Thailand and Southeast Asia
Rujipat Wasitthankasem, Sompong Vongpunsawad, Nipaporn Siripon, Chutima Suya, Phrutsada Chulothok, Kasemporn Chaiear, Pairaya Rujirojindakul, Sawan Kanjana, Apiradee Theamboonlers, Pisit Tangkijvanich, Yong Poovorawan
PLoS One. 2015; 10(5): e0126764. Published online 2015 May 11. doi: 10.1371/journal.pone.0126764
PMCID:
PMC4427325
AbstractArticlePDF–1.7M

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