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Select item 69856931.

Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4‐ATF3‐CHOP axis

Qin Tang, Liwen Ren, Jinyi Liu, Wan Li, Xiangjin Zheng, Jinhua Wang, Guanhua Du

Cell Prolif. 2020 Jan; 53(1): e12706. Published online 2019 Oct 23. doi: 10.1111/cpr.12706

Correction in:: Cell Prolif. 2024 Oct; 57(10): e13706.

PMCID:: PMC6985693

Abstract Article PDF–4.5M

Select item 67426462.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 66941323.

HENA, heterogeneous network-based data set for Alzheimer’s disease

Elena Sügis, Jerome Dauvillier, Anna Leontjeva, Priit Adler, Valerie Hindie, Thomas Moncion, Vincent Collura, Rachel Daudin, Yann Loe-Mie, Yann Herault, Jean-Charles Lambert, Henning Hermjakob, Tal Pupko, Jean-Christophe Rain, Ioannis Xenarios, Jaak Vilo, Michel Simonneau, Hedi Peterson

Sci Data. 2019; 6: 151. Published online 2019 Aug 14. doi: 10.1038/s41597-019-0152-0

PMCID:: PMC6694132

Abstract Article PDF–2.8M

Select item 43832294.

Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

Dmitry E Andreev, Patrick BF O'Connor, Ciara Fahey, Elaine M Kenny, Ilya M Terenin, Sergey E Dmitriev, Paul Cormican, Derek W Morris, Ivan N Shatsky, Pavel V Baranov

eLife. 2015; 4: e03971. Published online 2015 Jan 26. doi: 10.7554/eLife.03971

PMCID:: PMC4383229

Abstract Article PDF–3.4M

Select item 5091935.

Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

Krishna M. Vattem, Ronald C. Wek

Proc Natl Acad Sci U S A. 2004 Aug 3; 101(31): 11269–11274. Published online 2004 Jul 26. doi: 10.1073/pnas.0400541101

PMCID:: PMC509193

Abstract Article PDF–458K

Select item 515246.

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

T Hai, T Curran

Proc Natl Acad Sci U S A. 1991 May 1; 88(9): 3720–3724. doi: 10.1073/pnas.88.9.3720

PMCID:: PMC51524

Summary Page Browse PDF–1.2M

Select item 491797.

Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element.

B A Karpinski, G D Morle, J Huggenvik, M D Uhler, J M Leiden

Proc Natl Acad Sci U S A. 1992 Jun 1; 89(11): 4820–4824. doi: 10.1073/pnas.89.11.4820

PMCID:: PMC49179

Summary Page Browse PDF–1.3M

Select item 70102918.

1,25-hydroxyvitamin D3 decreases endoplasmic reticulum stress-induced inflammatory response in mammary epithelial cells

Gaiping Wen, Klaus Eder, Robert Ringseis

PLoS One. 2020; 15(2): e0228945. Published online 2020 Feb 10. doi: 10.1371/journal.pone.0228945

PMCID:: PMC7010291

Abstract Article PDF–3.1M

Select item 62513079.

XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response

Emily E. Fink, Sudha Moparthy, Archis Bagati, Anna Bianchi-Smiraglia, Brittany C. Lipchick, David W. Wolff, Matthew V. Roll, Jianmin Wang, Song Liu, Andrei V. Bakin, Eugene S. Kandel, Ann-Hwee Lee, Mikhail A. Nikiforov

Cell Rep. Author manuscript; available in PMC 2018 Nov 23.

Published in final edited form as: Cell Rep. 2018 Oct 2; 25(1): 212–223.e4. doi: 10.1016/j.celrep.2018.09.013

PMCID:: PMC6251307

Abstract Article PDF–2.5M

Select item 616432710.

Effects of Antioxidants in Reducing Accumulation of Fat in Hepatocyte

Jung-Pyo Yang, Ji-Hun Shin, Seung-Hwan Seo, Sang-Gyun Kim, Sang Hyung Lee, Eun-Hee Shin

Int J Mol Sci. 2018 Sep; 19(9): 2563. Published online 2018 Aug 29. doi: 10.3390/ijms19092563

PMCID:: PMC6164327

Abstract Article PDF–4.3M

Select item 605165511.

Amino acid deprivation triggers a novel GCN2-independent response leading to the transcriptional reactivation of non-native DNA sequences

Annarosaria De Vito, Massimo Lazzaro, Ilaria Palmisano, Davide Cittaro, Michela Riba, Dejan Lazarevic, Makoto Bannai, Davide Gabellini, Maria Vittoria Schiaffino

PLoS One. 2018; 13(7): e0200783. Published online 2018 Jul 18. doi: 10.1371/journal.pone.0200783

PMCID:: PMC6051655

Abstract Article PDF–8.9M

Select item 599775212.

Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

Juliane Hitzel, Eunjee Lee, Yi Zhang, Sofia Iris Bibli, Xiaogang Li, Sven Zukunft, Beatrice Pflüger, Jiong Hu, Christoph Schürmann, Andrea Estefania Vasconez, James A. Oo, Adelheid Kratzer, Sandeep Kumar, Flávia Rezende, Ivana Josipovic, Dominique Thomas, Hector Giral, Yannick Schreiber, Gerd Geisslinger, Christian Fork, Xia Yang, Fragiska Sigala, Casey E. Romanoski, Jens Kroll, Hanjoong Jo, Ulf Landmesser, Aldons J. Lusis, Dmitry Namgaladze, Ingrid Fleming, Matthias S. Leisegang, Jun Zhu, Ralf P. Brandes

Nat Commun. 2018; 9: 2292. Published online 2018 Jun 12. doi: 10.1038/s41467-018-04602-0

PMCID:: PMC5997752

Abstract Article PDF–3.1M

Select item 566678713.

Achiral Mannich-Base Curcumin Analogs Induce Unfolded Protein Response and Mitochondrial Membrane Depolarization in PANC-1 Cells

Gábor J. Szebeni, Árpád Balázs, Ildikó Madarász, Gábor Pócz, Ferhan Ayaydin, Iván Kanizsai, Roberta Fajka-Boja, Róbert Alföldi, László Hackler, Jr., László G. Puskás

Int J Mol Sci. 2017 Oct; 18(10): 2105. Published online 2017 Oct 7. doi: 10.3390/ijms18102105

PMCID:: PMC5666787

Abstract Article PDF–12M

Select item 563365514.

ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner

D Chen, Z Fan, M Rauh, M Buchfelder, I Y Eyupoglu, N Savaskan

Oncogene. 2017 Oct 5; 36(40): 5593–5608. Published online 2017 May 29. doi: 10.1038/onc.2017.146

PMCID:: PMC5633655

Abstract Article PDF–6.8M

Select item 558423915.

The oxido-metabolic driver ATF4 enhances temozolamide chemo-resistance in human gliomas

Daishi Chen, Manfred Rauh, Michael Buchfelder, Ilker Y. Eyupoglu, Nicolai Savaskan

Oncotarget. 2017 Aug 1; 8(31): 51164–51176. Published online 2017 May 9. doi: 10.18632/oncotarget.17737

PMCID:: PMC5584239

Abstract Article PDF–17M

Select item 548955716.

Pekinenin E Inhibits the Growth of Hepatocellular Carcinoma by Promoting Endoplasmic Reticulum Stress Mediated Cell Death

Lu Fan, Qingling Xiao, Yanyan Chen, Gang Chen, Jinao Duan, Weiwei Tao

Front Pharmacol. 2017; 8: 424. Published online 2017 Jun 29. doi: 10.3389/fphar.2017.00424

PMCID:: PMC5489557

Abstract Article PDF–3.4M

Select item 515832017.

Leishmania infantum Induces Mild Unfolded Protein Response in Infected Macrophages

Luca Galluzzi, Aurora Diotallevi, Mauro De Santi, Marcello Ceccarelli, Fabrizio Vitale, Giorgio Brandi, Mauro Magnani

PLoS One. 2016; 11(12): e0168339. Published online 2016 Dec 15. doi: 10.1371/journal.pone.0168339

PMCID:: PMC5158320

Abstract Article PDF–2.5M

Select item 504256718.

Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response

Thomas Lahlali, Marie-Laure Plissonnier, Cristina Romero-López, Maud Michelet, Benjamin Ducarouge, Alfredo Berzal-Herranz, Fabien Zoulim, Patrick Mehlen, Romain Parent

Cell Mol Gastroenterol Hepatol. 2016 May; 2(3): 281–301.e9. Published online 2016 Jan 9. doi: 10.1016/j.jcmgh.2015.12.011

PMCID:: PMC5042567

Abstract Article PDF–3.5M

Select item 502290019.

Combination of the histone deacetylase inhibitor depsipeptide and 5-fluorouracil upregulates major histocompatibility complex class II and p21 genes and activates caspase-3/7 in human colon cancer HCT-116 cells

Kouji Okada, Shuko Hakata, Jun Terashima, Toshie Gamou, Wataru Habano, Shogo Ozawa

Oncol Rep. 2016 Oct; 36(4): 1875–1885. Published online 2016 Aug 8. doi: 10.3892/or.2016.5008

PMCID:: PMC5022900

Abstract Article PDF–823K

Select item 498252120.

DNA Microarray Highlights Nrf2-Mediated Neuron Protection Targeted by Wasabi-Derived Isothiocyanates in IMR-32 Cells

Phoebe Zapanta Trio, Satoru Fujisaki, Shunsuke Tanigawa, Ayami Hisanaga, Kozue Sakao, De-Xing Hou

Gene Regul Syst Bio. 2016; 10: 73–83. Published online 2016 Aug 11. doi: 10.4137/GRSB.S39440

PMCID:: PMC4982521

Abstract Article PDF–1.6M

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