PMC Links for Nucleotide (Select 618468327) - PMC

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Select item 67814001.

CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma

Yongqiang Qi, Da Wang, Wenhua Huang, Bing Wang, Di Huang, Fei Xiong, Xiaoping Chen, Yongjun Chen

J Exp Clin Cancer Res. 2019; 38: 413. Published online 2019 Oct 7. doi: 10.1186/s13046-019-1415-5

PMCID:: PMC6781400

Abstract Article PDF–24M

Select item 66954902.

Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis

Jeffrey Vedanayagam, Walid K. Chatila, Bülent Arman Aksoy, Sonali Majumdar, Anders Jacobsen Skanderup, Emek Demir, Nikolaus Schultz, Chris Sander, Eric C. Lai

Nat Commun. 2019; 10: 3682. Published online 2019 Aug 15. doi: 10.1038/s41467-019-11610-1

PMCID:: PMC6695490

Abstract Article PDF–1.4M

Select item 66751283.

BCDIN3D regulates tRNA^His 3’ fragment processing

Calder W. Reinsborough, Hélène Ipas, Nathan S. Abell, Ryan M. Nottingham, Jun Yao, Sravan K. Devanathan, Samantha B. Shelton, Alan M. Lambowitz, Blerta Xhemalçe

PLoS Genet. 2019 Jul; 15(7): e1008273. Published online 2019 Jul 22. doi: 10.1371/journal.pgen.1008273

PMCID:: PMC6675128

Abstract Article PDF–2.8M

Select item 17160294.

Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer.

G R Bignell, F Canzian, M Shayeghi, M Stark, Y Y Shugart, P Biggs, J Mangion, R Hamoudi, J Rosenblatt, P Buu, S Sun, S S Stoffer, D E Goldgar, G Romeo, R S Houlston, S A Narod, M R Stratton, W D Foulkes

Am J Hum Genet. 1997 Nov; 61(5): 1123–1130. doi: 10.1086/301610

PMCID:: PMC1716029

Summary Page Browse PDF–1.4M

Select item 16841315.

An autosomal dominant form of adolescent multinodular goiter.

R M Couch, I A Hughes, D J DeSa, A Schiffrin, H Guyda, J S Winter

Am J Hum Genet. 1986 Dec; 39(6): 811–816.

PMCID:: PMC1684131

Summary Page Browse PDF–861K

Select item 11750716.

Alternative initiation and splicing in dicer gene expression in human breast cells

Charletha V Irvin-Wilson, Gautam Chaudhuri

Breast Cancer Res. 2005; 7(4): R563–R569. Published online 2005 May 16. doi: 10.1186/bcr1043

PMCID:: PMC1175071

Abstract Article PDF–669K

Select item 69592127.

Challenges in reporting pathogenic/potentially pathogenic variants in 94 cancer predisposing genes - in pediatric patients screened with NGS panels

Adela Chirita-Emandi, Nicoleta Andreescu, Cristian G. Zimbru, Paul Tutac, Smaranda Arghirescu, Margit Serban, Maria Puiu

Sci Rep. 2020; 10: 223. Published online 2020 Jan 14. doi: 10.1038/s41598-019-57080-9

PMCID:: PMC6959212

Abstract Article PDF–1.0M

Select item 68242588.

Biallelic loss of GNAS in a patient with pediatric medulloblastoma

Mari J. Tokita, Shareef Nahas, Benjamin Briggs, Denise M. Malicki, Jill P. Mesirov, Iris Anne C. Reyes, Lauge Farnaes, Michael L. Levy, Stephen F. Kingsmore, David Dimmock, John R. Crawford, Robert J. Wechsler-Reya

Cold Spring Harb Mol Case Stud. 2019 Oct; 5(5): a004572. doi: 10.1101/mcs.a004572

PMCID:: PMC6824258

Abstract Article PDF–2.5M

Select item 64684939.

Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks

Kaspar Burger, Margarita Schlackow, Monika Gullerova

Nucleic Acids Res. 2019 Apr 23; 47(7): 3467–3484. Published online 2019 Jan 22. doi: 10.1093/nar/gkz024

PMCID:: PMC6468493

Abstract Article PDF–5.0M

Select item 608183210.

Breast cancer patients suggestive of Li-Fraumeni syndrome: mutational spectrum, candidate genes, and unexplained heredity

Judith Penkert, Gunnar Schmidt, Winfried Hofmann, Stephanie Schubert, Maximilian Schieck, Bernd Auber, Tim Ripperger, Karl Hackmann, Marc Sturm, Holger Prokisch, Ursula Hille-Betz, Dorothea Mark, Thomas Illig, Brigitte Schlegelberger, Doris Steinemann

Breast Cancer Res. 2018; 20: 87. Published online 2018 Aug 7. doi: 10.1186/s13058-018-1011-1

PMCID:: PMC6081832

Abstract Article PDF–685K

Select item 555171011.

Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage

Kaspar Burger, Margarita Schlackow, Martin Potts, Svenja Hester, Shabaz Mohammed, Monika Gullerova

J Cell Biol. 2017 Aug 7; 216(8): 2373–2389. doi: 10.1083/jcb.201612131

PMCID:: PMC5551710

Abstract Article PDF–2.8M

Select item 542319012.

KLK6‐regulated miRNA networks activate oncogenic pathways in breast cancer subtypes

Konstantinos G. Sidiropoulos, Qiang Ding, Georgios Pampalakis, Nicole M.A. White, Peter Boulos, Georgia Sotiropoulou, George M. Yousef

Mol Oncol. 2016 Aug; 10(7): 993–1007. Published online 2016 Apr 8. doi: 10.1016/j.molonc.2016.03.008

PMCID:: PMC5423190

Abstract Article PDF–4.1M

Select item 482075013.

Revealing a new activity of the human Dicer DUF283 domain in vitro

Anna Kurzynska-Kokorniak, Maria Pokornowska, Natalia Koralewska, Weronika Hoffmann, Krystyna Bienkowska-Szewczyk, Marek Figlerowicz

Sci Rep. 2016; 6: 23989. Published online 2016 Apr 5. doi: 10.1038/srep23989

PMCID:: PMC4820750

Abstract Article PDF–1.2M

Select item 454150214.

Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells

Julian Wampfler, Elena A. Federzoni, Bruce E. Torbett, Martin F. Fey, Mario P. Tschan

J Leukoc Biol. 2015 Sep; 98(3): 357–363. Published online 2015 May 19. doi: 10.1189/jlb.1AB0514-258R

PMCID:: PMC4541502

Abstract Article

Select item 452460915.

A Novel WRN Frameshift Mutation Identified by Multiplex Genetic Testing in a Family with Multiple Cases of Cancer

Liu Yang, Guosheng Wang, Xinyi Zhao, Song Ye, Peng Shen, Weilin Wang, Shusen Zheng

PLoS One. 2015; 10(8): e0133020. Published online 2015 Aug 4. doi: 10.1371/journal.pone.0133020

PMCID:: PMC4524609

Abstract Article PDF–2.7M

Select item 441298516.

Biocomputational Characterization and Evolutionary Analysis of Bubaline Dicer1 Enzyme

Jasdeep Singh, Chandra Sekhar Mukhopadhyay, Jaspreet Singh Arora, Simarjeet Kaur

Asian-Australas J Anim Sci. 2015 Jun; 28(6): 876–887. doi: 10.5713/ajas.14.0767

PMCID:: PMC4412985

Abstract Article PDF–1.1M

Select item 400705917.

Comparative analysis of RNAi screening technologies at genome-scale reveals an inherent processing inefficiency of the plasmid-based shRNA hairpin

Bhavneet Bhinder, David Shum, Hakim Djaballah

Comb Chem High Throughput Screen. Author manuscript; available in PMC 2014 May 2.

Published in final edited form as: Comb Chem High Throughput Screen. 2014 Feb; 17(2): 98–113. doi: 10.2174/1386207317666140117101852

PMCID:: PMC4007059

Abstract Article PDF–4.1M

Select item 388468918.

Modulators of the microRNA biogenesis pathway via arrayed lentiviral enabled RNAi screening for drug and biomarker discovery

David Shum, Bhavneet Bhinder, Hakim Djaballah

Comb Chem High Throughput Screen. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Comb Chem High Throughput Screen. 2013 Dec; 16(10): 791–805. doi: 10.2174/1386207311301010004

PMCID:: PMC3884689

Abstract Article PDF–1.9M

Select item 384295419.

Genetic Variation in DROSHA 3’UTR Regulated by hsa-miR-27b Is Associated with Bladder Cancer Risk

Lin Yuan, Haiyan Chu, Meilin Wang, Xiaojian Gu, Danni Shi, Lan Ma, Dongyan Zhong, Mulong Du, Pu Li, Na Tong, Guangbo Fu, Chao Qin, Changjun Yin, Zhengdong Zhang

PLoS One. 2013; 8(11): e81524. Published online 2013 Nov 28. doi: 10.1371/journal.pone.0081524

PMCID:: PMC3842954

Abstract Article PDF–510K

Select item 341267920.

A Distinct Expression Pattern of the Long 3′-Untranslated Region Dicer mRNA and Its Implications for Posttranscriptional Regulation in Colorectal Cancer

Yasushi Hamaya, Shigeru Kuriyama, Tetsunari Takai, Ken-ichi Yoshida, Takanori Yamada, Mitsushige Sugimoto, Satoshi Osawa, Ken Sugimoto, Hiroaki Miyajima, Shigeru Kanaoka

Clin Transl Gastroenterol. 2012 Jul; 3(7): e17. Published online 2012 Jul 26. doi: 10.1038/ctg.2012.12