PMC Links for Nucleotide (Select 98991772) - PMC

Select item 67695861.

Polymorphisms of CYP2C8 Alter First-Electron Transfer Kinetics and Increase Catalytic Uncoupling

William R. Arnold, Susan Zelasko, Daryl D. Meling, Kimberly Sam, Aditi Das

Int J Mol Sci. 2019 Sep; 20(18): 4626. Published online 2019 Sep 18. doi: 10.3390/ijms20184626

PMCID:: PMC6769586

Select item 65629432.

Patients carrying CYP2C8*3 have shorter systemic paclitaxel exposure

Lauren A Marcath, Kelley M Kidwell, Adam C Robinson, Kiran Vangipuram, Monika L Burness, Jennifer J Griggs, Catherine Van Poznak, Anne F Schott, Daniel F Hayes, Norah Lynn Henry, Daniel L Hertz

Pharmacogenomics. 2019 Jan; 20(2): 95–104. Published online 2018 Dec 6. doi: 10.2217/pgs-2018-0162

PMCID:: PMC6562943

Abstract Article PDF–492K

Select item 3322423.

Sequence of a human liver cytochrome P-450 cDNA clone.

A Y Kolyada

Nucleic Acids Res. 1990 Sep 25; 18(18): 5550. doi: 10.1093/nar/18.18.5550

PMCID:: PMC332242

Summary Page Browse PDF–132K

Select item 63899774.

Dengue virus nonstructural 3 protein interacts directly with human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and reduces its glycolytic activity

Emiliana M. Silva, Jonas N. Conde, Diego Allonso, Gustavo T. Ventura, Diego R. Coelho, Pedro Henrique Carneiro, Manuela L. Silva, Marciano V. Paes, Kíssila Rabelo, Gilberto Weissmuller, Paulo Mascarello Bisch, Ronaldo Mohana-Borges

Sci Rep. 2019; 9: 2651. Published online 2019 Feb 25. doi: 10.1038/s41598-019-39157-7

PMCID:: PMC6389977

Abstract Article PDF–2.6M

Select item 48342465.

Sex- and Isoform-Specific Mechanism of Neuroprotection by Transgenic Expression of P450 Epoxygenase in Vascular Endothelium

Jia Jia, Catherine M Davis, Wenri Zhang, Matthew L. Edin, Sari Jouihan, Taiping Jia, J. Alyce Bradbury, Joan P. Graves, Laura M. DeGraff, Craig R. Lee, Oline Ronnekleiv, Ruikang Wang, Yun Xu, Darryl C. Zeldin, Nabil J. Alkayed

Exp Neurol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Exp Neurol. 2016 May; 279: 75–85. Published online 2016 Feb 20. doi: 10.1016/j.expneurol.2016.02.016

PMCID:: PMC4834246

Abstract Article PDF–2.7M

Select item 43087286.

In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes

Anuradha Ramamoorthy, Todd C. Skaar

Drug Metab Lett. Author manuscript; available in PMC 2015 Jan 28.

Published in final edited form as: Drug Metab Lett. 2011 Apr; 5(2): 126–131. doi: 10.2174/187231211795305258

PMCID:: PMC4308728

Abstract Article PDF–466K

Select item 42079777.

Targeting of Splice Variants of Human Cytochrome P450 2C8 (CYP2C8) to Mitochondria and Their Role in Arachidonic Acid Metabolism and Respiratory Dysfunction

Prachi Bajpai, Satish Srinivasan, Jyotirmoy Ghosh, Leslie D. Nagy, Shouzou Wei, F. Peter Guengerich, Narayan G. Avadhani

J Biol Chem. 2014 Oct 24; 289(43): 29614–29630. Published online 2014 Aug 26. doi: 10.1074/jbc.M114.583062

PMCID:: PMC4207977

Abstract Article PDF–3.8M

Select item 40031618.

ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes

Xin-ming Qi, Ling-ling Miao, Yan Cai, Li-kun Gong, Jin Ren

Acta Pharmacol Sin. 2013 Sep 5; 34(9): 1229–1236. Published online 2013 Jul 29. doi: 10.1038/aps.2013.62

PMCID:: PMC4003161

Abstract Article PDF–1.8M

Select item 32482889.

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

Dipak Panigrahy, Matthew L. Edin, Craig R. Lee, Sui Huang, Diane R. Bielenberg, Catherine E. Butterfield, Carmen M. Barnés, Akiko Mammoto, Tadanori Mammoto, Ayala Luria, Ofra Benny, Deviney M. Chaponis, Andrew C. Dudley, Emily R. Greene, Jo-Anne Vergilio, Giorgio Pietramaggiori, Sandra S. Scherer-Pietramaggiori, Sarah M. Short, Meetu Seth, Fred B. Lih, Kenneth B. Tomer, Jun Yang, Reto A. Schwendener, Bruce D. Hammock, John R. Falck, Vijaya L. Manthati, Donald E. Ingber, Arja Kaipainen, Patricia A. D’Amore, Mark W. Kieran, Darryl C. Zeldin

J Clin Invest. 2012 Jan 3; 122(1): 178–191. Published online 2011 Dec 19. doi: 10.1172/JCI58128

PMCID:: PMC3248288

Abstract Article PDF–5.5M

Select item 319892710.

Upregulation of CYP 450s expression of immortalized hepatocyte-like cells derived from mesenchymal stem cells by enzyme inducers

Khanit Sa-ngiamsuntorn, Adisak Wongkajornsilp, Kanda Kasetsinsombat, Sunisa Duangsa-ard, Lalana Nuntakarn, Suparerk Borwornpinyo, Pravit Akarasereenont, Somchai Limsrichamrern, Suradej Hongeng

BMC Biotechnol. 2011; 11: 89. Published online 2011 Sep 30. doi: 10.1186/1472-6750-11-89

PMCID:: PMC3198927

Abstract Article PDF–3.5M

Select item 311039311.

Polymorphisms in ABCB1 and ERCC2 associated with ovarian cancer outcome

Prema Peethambaram, Brooke L Fridley, Robert A Vierkant, Melissa C Larson, Kimberly R Kalli, Elaine A Elliott, Ann L Oberg, Kristin L White, David N Rider, Gary L Keeney, Julie M Cunningham, Lynn C Hartmann, Ellen L Goode

Int J Mol Epidemiol Genet. 2011 May 15; 2(2): 185–195. Published online 2011 May 2.

PMCID:: PMC3110393

Abstract Article PDF–728K

Select item 302338712.

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice

Yangmei Deng, Matthew L. Edin, Katherine N. Theken, Robert N. Schuck, Gordon P. Flake, M. Alison Kannon, Laura M. DeGraff, Fred B. Lih, Julie Foley, J. Alyce Bradbury, Joan P. Graves, Kenneth B. Tomer, John R. Falck, Darryl C. Zeldin, Craig R. Lee

FASEB J. 2011 Feb; 25(2): 703–713. doi: 10.1096/fj.10-171488

PMCID:: PMC3023387

Abstract Article

Select item 299690313.

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice

Craig R. Lee, John D. Imig, Matthew L. Edin, Julie Foley, Laura M. DeGraff, J. Alyce Bradbury, Joan P. Graves, Fred B. Lih, James Clark, Page Myers, A. Ligon Perrow, Adrienne N. Lepp, M. Alison Kannon, Oline K. Ronnekleiv, Nabil J. Alkayed, John R. Falck, Kenneth B. Tomer, Darryl C. Zeldin

FASEB J. 2010 Oct; 24(10): 3770–3781. doi: 10.1096/fj.10-160119

PMCID:: PMC2996903

Abstract Article

Select item 265180614.

Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes

Niresh Hariparsad, Xiaoyan Chu, Jocelyn Yabut, Paul Labhart, Dylan P. Hartley, Xudong Dai, Raymond Evers

Nucleic Acids Res. 2009 Mar; 37(4): 1160–1173. Published online 2009 Jan 7. doi: 10.1093/nar/gkn1047

PMCID:: PMC2651806

Abstract Article PDF–176K

Select item 258498415.

Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis

Anke C. Webler, U. Ruth Michaelis, Rüdiger Popp, Eduardo Barbosa-Sicard, Andiappan Murugan, John R. Falck, Beate Fisslthaler, Ingrid Fleming

Am J Physiol Cell Physiol. 2008 Nov; 295(5): C1292–C1301. Published online 2008 Sep 11. doi: 10.1152/ajpcell.00230.2008

PMCID:: PMC2584984

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