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Items: 1 to 20 of 40

1.
Endothelial TLR4 and the microbiome drive cerebral cavernous malformations
Alan T. Tang, Jaesung P. Choi, Jonathan J. Kotzin, Yiqing Yang, Courtney C. Hong, Nicholas Hobson, Romuald Girard, Hussein A. Zeineddine, Rhonda Lightle, Thomas Moore, Ying Cao, Robert Shenkar, Mei Chen, Patricia Mericko, Jisheng Yang, Li Li, Ceylan Tanes, Dmytro Kobuley, Urmo Võsa, Kevin J. Whitehead, Dean Y. Li, Lude Franke, Blaine Hart, Markus Schwaninger, Jorge Henao-Mejia, Leslie Morrison, Helen Kim, Issam A. Awad, Xiangjian Zheng, Mark L. Kahn
Nature. Author manuscript; available in PMC 2018 Jan 8.
Published in final edited form as: Nature. 2017 May 18; 545(7654): 305–310. Published online 2017 May 10. doi: 10.1038/nature22075
PMCID:
PMC5757866
AbstractArticlePDF–5.1M
2.
Neutrophil ageing is regulated by the microbiome
Dachuan Zhang, Grace Chen, Deepa Manwani, Arthur Mortha, Chunliang Xu, Jeremiah J. Faith, Robert D. Burk, Yuya Kunisaki, Jung-Eun Jang, Christoph Scheiermann, Miriam Merad, Paul S. Frenette
Nature. Author manuscript; available in PMC 2016 Mar 24.
Published in final edited form as: Nature. 2015 Sep 24; 525(7570): 528–532. Published online 2015 Sep 16. doi: 10.1038/nature15367
PMCID:
PMC4712631
AbstractArticlePDF–4.2M
3.
WDFY1 mediates TLR3/4 signaling by recruiting TRIF
Yun-Hong Hu, Yu Zhang, Li-Qun Jiang, Shuai Wang, Cao-Qi Lei, Ming-Shun Sun, Hong-Bing Shu, Yu Liu
EMBO Rep. 2015 Apr; 16(4): 447–455. Published online 2015 Mar 3. doi: 10.15252/embr.201439637
PMCID:
PMC4388611
AbstractArticlePDF–1.2M
4.
Cleavage of Fibrinogen by Proteinases Elicits Allergic Responses Through Toll-Like Receptor 4
Valentine Ongeri Millien, Wen Lu, Joanne Shaw, Xiaoyi Yuan, Garbo Mak, Luz Roberts, Li-Zhen Song, J. Morgan Knight, Chad J. Creighton, Amber Luong, Farrah Kheradmand, David B. Corry
Science. Author manuscript; available in PMC 2014 Jan 22.
Published in final edited form as: Science. 2013 Aug 16; 341(6147): 792–796. doi: 10.1126/science.1240342
PMCID:
PMC3898200
AbstractArticlePDF–1.2M
5.
The TLR4 Antagonist, Eritoran, Protects Mice from Lethal Influenza Infection
Kari Ann Shirey, Wendy Lai, Alison J. Scott, Michael Lipsky, Pragnesh Mistry, Lioubov M. Pletneva, Christopher L. Karp, Jaclyn McAlees, Theresa L. Gioannini, Jerrold Weiss, Wilbur H. Chen, Robert K. Ernst, Daniel P. Rossignol, Fabian Gusovsky, Jorge C. G. Blanco, Stefanie N. Vogel
Nature. Author manuscript; available in PMC 2013 Jul 29.
Published in final edited form as: Nature. 2013 May 23; 497(7450): 498–502. Published online 2013 May 1. doi: 10.1038/nature12118
PMCID:
PMC3725830
AbstractArticlePDF–3.2M
6.
Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines
Ashley St John, Soman N Abraham
Nat Med. Author manuscript; available in PMC 2013 Apr 4.
Published in final edited form as: Nat Med. 2009 Nov; 15(11): 1259–1265. Published online 2009 Oct 25. doi: 10.1038/nm.2036
PMCID:
PMC3616497
AbstractArticlePDF–5.1M
7.
The Asp299Gly Polymorphism Alters TLR4 Signaling by Interfering with Recruitment of MyD88 and TIR domain-containing adapter inducing IFN-β
Leandra Figueroa, Yanbao Xiong, Chang Song, Wenji Piao, Stefanie N. Vogel, Andrei E. Medvedev
J Immunol. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: J Immunol. 2012 May 1; 188(9): 4506–4515. Published online 2012 Apr 2. doi: 10.4049/jimmunol.1200202
PMCID:
PMC3531971
AbstractArticlePDF–1.8M
8.
Successful Transmission of a Retrovirus Depends on the Commensal Microbiota
Melissa Kane, Laure K. Case, Karyl Kopaskie, Alena Kozlova, Cameron MacDearmid, Alexander V. Chervonsky, Tatyana V. Golovkina
Science. Author manuscript; available in PMC 2012 Dec 11.
Published in final edited form as: Science. 2011 Oct 14; 334(6053): 245–249. doi: 10.1126/science.1210718
PMCID:
PMC3519937
AbstractArticlePDF–1.3M
9.
Structural Analyses of Human Toll-like Receptor 4 Polymorphisms D299G and T399I
Umeharu Ohto, Natsuko Yamakawa, Sachiko Akashi-Takamura, Kensuke Miyake, Toshiyuki Shimizu
J Biol Chem. 2012 Nov 23; 287(48): 40611–40617. Published online 2012 Oct 10. doi: 10.1074/jbc.M112.404608
PMCID:
PMC3504774
AbstractArticlePDF–2.0M
10.
TLR signaling augments macrophage bactericidal activity through mitochondrial ROS
A. Phillip West, Igor E. Brodsky, Christoph Rahner, Dong Kyun Woo, Hediye Erdjument-Bromage, Paul Tempst, Matthew C. Walsh, Yongwon Choi, Gerald S. Shadel, Sankar Ghosh
Nature. Author manuscript; available in PMC 2012 Sep 28.
Published in final edited form as: Nature. 2011 Apr 28; 472(7344): 476–480. doi: 10.1038/nature09973
PMCID:
PMC3460538
AbstractArticlePDF–633K
11.
Protective Role for TLR4 Signaling in Atherosclerosis Progression as Revealed by Infection with a Common Oral Pathogen
Chie Hayashi, George Papadopoulos, Cynthia V. Gudino, Ellen O. Weinberg, Kenneth R. Barth, Andrés G. Madrigal, Yang Chen, Hua Ning, Michael LaValley, Frank C. Gibson, III, James A. Hamilton, Caroline A. Genco
J Immunol. 2012 Oct 1; 189(7): 3681–3688. Published online 2012 Sep 5. doi: 10.4049/jimmunol.1201541
PMCID:
PMC3448820
AbstractArticlePDF–1.1M
12.
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
Jorge Henao-Mejia, Eran Elinav, Cheng-Cheng Jin, Liming Hao, Wajahat Z. Mehal, Till Strowig, Christoph A. Thaiss, Andrew L. Kau, Stephanie C. Eisenbarth, Michael J. Jurczak, Joao-Paulo Camporez, Gerald I. Shulman, Jeffrey I. Gordon, Hal M. Hoffman, Richard A. Flavell
Nature. Author manuscript; available in PMC 2012 Aug 9.
Published in final edited form as: Nature. 2012 Feb 9; 482(7384): 179–185. Published online 2012 Feb 1. doi: 10.1038/nature10809
PMCID:
PMC3276682
AbstractArticlePDF–2.1M
13.
CD14 controls the LPS-induced endocytosis of Toll-like Receptor 4
Ivan Zanoni, Renato Ostuni, Lorri R. Marek, Simona Barresi, Roman Barbalat, Gregory M. Barton, Fancesca Granucci, Jonathan C. Kagan
Cell. Author manuscript; available in PMC 2012 Nov 11.
Published in final edited form as: Cell. 2011 Nov 11; 147(4): 868–880. doi: 10.1016/j.cell.2011.09.051
PMCID:
PMC3217211
ArticlePDF–3.0M
14.
Programming the magnitude and persistence of antibody responses with innate immunity
Sudhir Pai Kasturi, Ioanna Skountzou, Randy A. Albrecht, Dimitrios Koutsonanos, Tang Hua, Helder Nakaya, Rajesh Ravindran, Shelley Stewart, Munir Alam, Marcin Kwissa, Francois Villinger, Niren Murthy, John Steel, Joshy Jacob, Robert J. Hogan, Adolfo García-Sastre, Richard Compans, Bali Pulendran
Nature. Author manuscript; available in PMC 2011 Aug 24.
Published in final edited form as: Nature. 2011 Feb 24; 470(7335): 543–547. doi: 10.1038/nature09737
PMCID:
PMC3057367
AbstractArticlePDF–1.1M
15.
Identification of a novel human MD-2 splice variant that negatively regulates LPS-induced Toll-like receptor 4 signaling
Pearl Gray, Kathrin S. Michelsen, Cherilyn M. Sirois, Emily Lowe, Kenichi Shimada, Timothy R. Crother, Shuang Chen, Constantinos Brikos, Yonca Bulut, Eicke Latz, David Underhill, Moshe Arditi
J Immunol. Author manuscript; available in PMC 2011 Jun 1.
Published in final edited form as: J Immunol. 2010 Jun 1; 184(11): 6359–6366. Published online 2010 Apr 30. doi: 10.4049/jimmunol.0903543
PMCID:
PMC3057206
AbstractArticlePDF–1.2M
16.
Polymorphisms in Toll-like receptor 4 (TLR4) are associated with protection against leprosy
P.-Y. Bochud, D. Sinsimer, A. Aderem, M. R. Siddiqui, P. Saunderson, S. Britton, I. Abraham, A. Tadesse Argaw, M. Janer, T. R. Hawn, G. Kaplan
Eur J Clin Microbiol Infect Dis. Author manuscript; available in PMC 2011 Jan 6.
Published in final edited form as: Eur J Clin Microbiol Infect Dis. 2009 Sep; 28(9): 1055–1065. Published online 2009 May 9. doi: 10.1007/s10096-009-0746-0
PMCID:
PMC3016895
AbstractArticlePDF–358K
17.
Lack of antibody affinity maturation due to poor Toll stimulation led to enhanced RSV disease
Maria Florencia Delgado, Silvina Coviello, A. Clara Monsalvo, Guillermina A. Melendi, Johanna Zea Hernandez, Juan P. Batalle, Leandro Diaz, Alfonsina Trento, Herng-Yu Chang, Wayne Mitzner, Jeffrey Ravetch, José A. Melero, Pablo M. Irusta, Fernando P. Polack
Nat Med. Author manuscript; available in PMC 2010 Nov 18.
Published in final edited form as: Nat Med. 2009 Jan; 15(1): 34–41. Published online 2008 Dec 14. doi: 10.1038/nm.1894
PMCID:
PMC2987729
AbstractArticlePDF–2.4M
18.
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein
Aurelien Trompette, Senad Divanovic, Alberto Visintin, Carine Blanchard, Rashmi S. Hegde, Rajat Madan, Peter S. Thorne, Marsha Wills-Karp, Theresa L. Gioannini, Jerry P. Weiss, Christopher L. Karp
Nature. Author manuscript; available in PMC 2010 Mar 22.
Published in final edited form as: Nature. 2009 Jan 29; 457(7229): 585–588. Published online 2008 Dec 7. doi: 10.1038/nature07548
PMCID:
PMC2843411
AbstractArticlePDF–1.9M
19.
House dust mite allergen induces asthma via TLR4 triggering of airway structural cells
Hamida HAMMAD, Marcello CHIEPPA, Frederic PERROS, Monique A. WILLART, Ronald N. GERMAIN, Bart N. LAMBRECHT
Nat Med. Author manuscript; available in PMC 2009 Dec 5.
Published in final edited form as: Nat Med. 2009 Apr; 15(4): 410–416. Published online 2009 Mar 29. doi: 10.1038/nm.1946
PMCID:
PMC2789255
AbstractArticlePDF–2.4M
20.
TLR4 and TLR5 induce distinct types of vasculitis
Jiusheng Deng, Wei Ma-Krupa, Andrew T. Gewirtz, Brian R. Younge, Jörg J. Goronzy, Cornelia M. Weyand
Circ Res. Author manuscript; available in PMC 2010 Feb 27.
Published in final edited form as: Circ Res. 2009 Feb 27; 104(4): 488–495. Published online 2009 Jan 15. doi: 10.1161/CIRCRESAHA.108.185777
PMCID:
PMC2731717
AbstractArticlePDF–4.8M

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