PMC Links for OMIM (Select 604378) - PMC

Select item 70475891.

Tlr9 and Beclin 1 Cross-Talk Regulates Muscle AMPK Activation in Exercise

Yang Liu, Phong T. Nguyen, Xun Wang, Yuting Zhao, Corbin E. Meacham, Zhongju Zou, Bogdan Bordieanu, Manuel Johanns, Didier Vertommen, Tobias Wijshake, Herman May, Guanghua Xiao, Sanae Shoji-Kawata, Mark H. Rider, Sean J. Morrison, Prashant Mishra, Beth Levine

Nature. Author manuscript; available in PMC 2020 Aug 12.

Published in final edited form as: Nature. 2020 Feb; 578(7796): 605–609. Published online 2020 Feb 12. doi: 10.1038/s41586-020-1992-7

PMCID:: PMC7047589

Abstract Article PDF–3.8M

Select item 68773382.

Myeloid loss of Beclin 1 promotes PD-L1^hi precursor B cell lymphoma development

Peng Tan, Lian He, Changsheng Xing, Jingrong Mao, Xiao Yu, Motao Zhu, Lixia Diao, Leng Han, Yubin Zhou, M. James You, Helen Y. Wang, Rong-Fu Wang

J Clin Invest. 2019 Dec 2; 129(12): 5261–5277. Published online 2019 Oct 28. doi: 10.1172/JCI127721

PMCID:: PMC6877338

Abstract Article PDF–17M

Select item 59920973.

Disruption of the beclin 1/Bcl-2 autophagy regulatory complex promotes longevity in mice

Álvaro F. Fernández, Salwa Sebti, Yongjie Wei, Zhongju Zou, Mingjun Shi, Kathryn L. McMillan, Congcong He, Tabitha Ting, Yang Liu, Wei-Chung Chiang, Denise K. Marciano, Gabriele G. Schiattarella, Govind Bhagat, Orson W. Moe, Ming Chang Hu, Beth Levine

Nature. Author manuscript; available in PMC 2018 Nov 30.

Published in final edited form as: Nature. 2018 Jun; 558(7708): 136–140. Published online 2018 May 30. doi: 10.1038/s41586-018-0162-7

Correction in:: Nature. 2018 Jun 19

PMCID:: PMC5992097

Abstract Article PDF–2.0M

Select item 55705064.

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

Altea Rocchi, Soh Yamamoto, Tabitha Ting, Yuying Fan, Katherine Sadleir, Yigang Wang, Weiran Zhang, Sui Huang, Beth Levine, Robert Vassar, Congcong He

PLoS Genet. 2017 Aug; 13(8): e1006962. Published online 2017 Aug 14. doi: 10.1371/journal.pgen.1006962

PMCID:: PMC5570506

Abstract Article PDF–11M

Select item 54203145.

Polyglutamine tracts regulate beclin 1-dependent autophagy

Avraham Ashkenazi, Carla F. Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C. Hardenberg, Sara Imarisio, Fiona M. Menzies, David C. Rubinsztein

Nature. Author manuscript; available in PMC 2017 Oct 26.

Published in final edited form as: Nature. 2017 May 4; 545(7652): 108–111. Published online 2017 Apr 26. doi: 10.1038/nature22078

PMCID:: PMC5420314

Abstract Article PDF–5.3M

Select item 39177136.

EGFR-Mediated Phosphorylation of Beclin 1 in Autophagy Suppression, Tumor Progression and Tumor Chemoresistance

Yongjie Wei, Zhongju Zou, Nils Becker, Matthew Anderson, Rhea Sumpter, Jr., Guanghua Xiao, Lisa Kinch, Prasad Koduru, Christhunesa S. Christudass, Robert W. Veltri, Nick V. Grishin, Michael Peyton, John Minna, Govind Bhagat, Beth Levine

Cell. Author manuscript; available in PMC 2014 Mar 12.

Published in final edited form as: Cell. 2013 Sep 12; 154(6): 1269–1284. doi: 10.1016/j.cell.2013.08.015

PMCID:: PMC3917713

Abstract Article PDF–6.2M

Select item 37886417.

Identification of a candidate therapeutic autophagy–inducing peptide

Sanae Shoji-Kawata, Rhea Sumpter, Jr, Matthew Leveno, Grant R. Campbell, Zhongju Zou, Lisa Kinch, Angela D. Wilkins, Qihua Sun, Kathrin Pallauf, Donna MacDuff, Carlos Huerta, Herbert W. Virgin, J. Bernd Helms, Ruud Eerland, Sharon A. Tooze, Ramnik Xavier, Deborah J. Lenschow, Ai Yamamoto, David King, Olivier Lichtarge, Nick V. Grishin, Stephen A. Spector, Dora V. Kaloyanova, Beth Levine

Nature. Author manuscript; available in PMC 2013 Oct 2.

Published in final edited form as: Nature. 2013 Feb 14; 494(7436): 201–206. Published online 2013 Jan 30. doi: 10.1038/nature11866

PMCID:: PMC3788641

Abstract Article PDF–1.5M

Select item 35074428.

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

Richard C. Wang, Yongjie Wei, Zhenyi An, Zhongju Zou, Guanghua Xiao, Govind Bhagat, Michael White, Julia Reichelt, Beth Levine

Science. Author manuscript; available in PMC 2012 Nov 27.

Published in final edited form as: Science. 2012 Nov 16; 338(6109): 956–959. Published online 2012 Oct 25. doi: 10.1126/science.1225967

PMCID:: PMC3507442

Abstract Article PDF–2.2M

Select item 34411479.

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

Junli Liu, Hongguang Xia, Minsu Kim, Lihua Xu, Ying Li, Lihong Zhang, Yu Cai, Helin Vakifahmetoglu Norberg, Tao Zhang, Tsuyoshi Furuya, Minzhi Jin, Zhimin Zhu, Huanchen Wang, Jia Yu, Yanxia Li, Yan Hao, Augustine Choi, Hengming Ke, Dawei Ma, Junying Yuan

Cell. Author manuscript; available in PMC 2012 Sep 13.

Published in final edited form as: Cell. 2011 Sep 30; 147(1): 223–234. doi: 10.1016/j.cell.2011.08.037

PMCID:: PMC3441147

Abstract Article PDF–4.7M

Select item 266438910.

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1- phosphatidylinositol 3-kinase complex

Yun Zhong, Qing Jun Wang, Xianting Li, Ying Yan, Jonathan M. Backer, Brian T. Chait, Nathaniel Heintz, Zhenyu Yue

Nat Cell Biol. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: Nat Cell Biol. 2009 Apr; 11(4): 468–476. Published online 2009 Mar 8. doi: 10.1038/ncb1854

PMCID:: PMC2664389

Abstract Article PDF–4.3M

Select item 239128411.

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice

Fiona Pickford, Eliezer Masliah, Markus Britschgi, Kurt Lucin, Ramya Narasimhan, Philipp A. Jaeger, Scott Small, Brian Spencer, Edward Rockenstein, Beth Levine, Tony Wyss-Coray

J Clin Invest. 2008 Jun 2; 118(6): 2190–2199. Published online 2008 May 22. doi: 10.1172/JCI33585

PMCID:: PMC2391284

Abstract Article PDF–1.4M

Select item 29991112.

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

Zhenyu Yue, Shengkan Jin, Chingwen Yang, Arnold J. Levine, Nathaniel Heintz

Proc Natl Acad Sci U S A. 2003 Dec 9; 100(25): 15077–15082. Published online 2003 Dec 1. doi: 10.1073/pnas.2436255100

PMCID:: PMC299911

Abstract Article PDF–761K

Select item 29700213.

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Xueping Qu, Jie Yu, Govind Bhagat, Norihiko Furuya, Hanina Hibshoosh, Andrea Troxel, Jeffrey Rosen, Eeva-Liisa Eskelinen, Noboru Mizushima, Yoshinori Ohsumi, Giorgio Cattoretti, Beth Levine

J Clin Invest. 2003 Dec 15; 112(12): 1809–1820. doi: 10.1172/JCI20039

PMCID:: PMC297002

Abstract Article PDF–13M

Select item 11026914.

Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein

Xiao Huan Liang, Linda K. Kleeman, Hui Hui Jiang, Gerald Gordon, James E. Goldman, Gail Berry, Brian Herman, Beth Levine

J Virol. 1998 Nov; 72(11): 8586–8596. doi: 10.1128/jvi.72.11.8586-8596.1998

PMCID:: PMC110269

Abstract Article PDF–8.5M

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