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Items: 1 to 20 of 22

1.
A PGC1a-mediated transcriptional axis suppresses melanoma metastasis
Chi Luo, Ji-Hong Lim, Yoonjin Lee, Scott R. Granter, Ajith Thomas, Francisca Vazquez, Hans R. Widlund, Pere Puigserver
Nature. Author manuscript; available in PMC 2017 Mar 15.
Published in final edited form as: Nature. 2016 Sep 15; 537(7620): 422–426. Published online 2016 Aug 31. doi: 10.1038/nature19347
PMCID:
PMC5161587
AbstractArticlePDF–3.3M
2.
PGC1a-dependent NAD biosynthesis links oxidative metabolism to renal protection
Mei T. Tran, Zsuzsanna K. Zsengeller, Anders H. Berg, Eliyahu V. Khankin, Manoj K. Bhasin, Wondong Kim, Clary B. Clish, Isaac E. Stillman, S. Ananth Karumanchi, Eugene P. Rhee, Samir M. Parikh
Nature. Author manuscript; available in PMC 2016 Sep 16.
Published in final edited form as: Nature. 2016 Mar 24; 531(7595): 528–532. Published online 2016 Mar 16. doi: 10.1038/nature17184
PMCID:
PMC4909121
AbstractArticlePDF–4.3M
3.
IRF4 is a key thermogenic transcriptional partner of PGC-1α
Xingxing Kong, Alexander Banks, Tiemin Liu, Lawrence Kazak, Rajesh R. Rao, Paul Cohen, Xun Wang, Songtao Yu, James C. Lo, Yu-Hua Tseng, Aaron M. Cypess, Ruidan Xue, Sandra Kleiner, Sona Kang, Bruce M. Spiegelman, Evan D. Rosen
Cell. Author manuscript; available in PMC 2015 Jul 3.
Published in final edited form as: Cell. 2014 Jul 3; 158(1): 69–83. doi: 10.1016/j.cell.2014.04.049
PMCID:
PMC4116691
AbstractArticlePDF–2.5M
4.
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway
Christiane D. Wrann, James P. White, John Salogiannnis, Dina Laznik-Bogoslavski, Jun Wu, Di Ma, Jiandie D. Lin, Michael E. Greenberg, Bruce M. Spiegelman
Cell Metab. Author manuscript; available in PMC 2014 Nov 5.
Published in final edited form as: Cell Metab. 2013 Nov 5; 18(5): 649–659. Published online 2013 Oct 10. doi: 10.1016/j.cmet.2013.09.008
PMCID:
PMC3980968
AbstractArticlePDF–1.9M
5.
Telomere dysfunction induces metabolic and mitochondrial compromise
Ergün Sahin, Simona Colla, Marc Liesa, Javid Moslehi, Florian L. Müller, Mira Guo, Marcus Cooper, Darrell Kotton, Attila J. Fabian, Carl Walkey, Richard S. Maser, Giovanni Tonon, Friedrich Foerster, Robert Xiong, Y. Alan Wang, Sachet A. Shukla, Mariela Jaskelioff, Eric S. Martin, Timothy P. Heffernan, Alexei Protopopov, Elena Ivanova, John E. Mahoney, Maria Kost-Alimova, Samuel R. Perry, Roderick Bronson, Ronglih Liao, Richard Mulligan, Orian S. Shirihai, Lynda Chin, Ronald A. DePinho
Nature. Author manuscript; available in PMC 2013 Aug 13.
Published in final edited form as: Nature. 2011 Feb 17; 470(7334): 359–365. Published online 2011 Feb 9. doi: 10.1038/nature09787
Correction in:
volume 475 on page 254
PMCID:
PMC3741661
AbstractArticlePDF–1.4M
6.
A PGC1a-dependent myokine that drives browning of white fat and thermogenesis
Pontus Boström, Jun Wu, Mark P. Jedrychowski, Anisha Korde, Li Ye, James C. Lo, Kyle A. Rasbach, Elisabeth Almer Boström, Jang Hyun Choi, Jonathan Z. Long, Shingo Kajimura, Maria Cristina Zingaretti, Birgitte F. Vind, Hua Tu, Saverio Cinti, Kurt Højlund, Steven P. Gygi, Bruce M. Spiegelman
Nature. Author manuscript; available in PMC 2012 Dec 14.
Published in final edited form as: Nature. 2012 Jan 26; 481(7382): 463–468. Published online 2012 Jan 11. doi: 10.1038/nature10777
PMCID:
PMC3522098
AbstractArticlePDF–1.4M
7.
A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy
Jorge L. Ruas, James P. White, Rajesh R. Rao, Sandra Kleiner, Kevin T. Brannan, Brooke C. Harrison, Nicholas P. Greene, Jun Wu, Jennifer L. Estall, Brian A. Irving, Ian R. Lanza, Kyle A. Rasbach, Mitsuharu Okutsu, K. Sreekumaran Nair, Zhen Yan, Leslie A. Leinwand, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2013 Dec 7.
Published in final edited form as: Cell. 2012 Dec 7; 151(6): 1319–1331. doi: 10.1016/j.cell.2012.10.050
PMCID:
PMC3520615
AbstractArticlePDF–5.1M
8.
Cardiac Angiogenic Imbalance Leads to Peri-partum Cardiomyopathy
Ian S. Patten, Sarosh Rana, Sajid Shahul, Glenn C Rowe, Cholsoon Jang, Laura Liu, Michele R. Hacker, Julie S. Rhee, John Mitchell, Feroze Mahmood, Phil Hess, Caitlin Farrell, Nicole Koulisis, Eliyahu V Khankin, Suzanne D. Burke, Igor Tudorache, Johann Bauersachs, Federica del Monte, Denise Hilfiker-Kleiner, S. Ananth Karumanchi, Zoltan Arany
Nature. Author manuscript; available in PMC 2012 Nov 17.
Published in final edited form as: Nature. 2012 May 17; 485(7398): 333–338. Published online 2012 May 9. doi: 10.1038/nature11040
PMCID:
PMC3356917
AbstractArticlePDF–1.6M
9.
Transcriptional coactivator PGC-1α promotes peroxisomal remodeling and biogenesis
Alessia Bagattin, Lynne Hugendubler, Elisabetta Mueller
Proc Natl Acad Sci U S A. 2010 Nov 23; 107(47): 20376–20381. Published online 2010 Nov 8. doi: 10.1073/pnas.1009176107
PMCID:
PMC2996647
AbstractArticlePDF–1.0M
10.
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
Yu-Hua Tseng, Efi Kokkotou, Tim J. Schulz, Tian Lian Huang, Jonathon N. Winnay, Cullen M. Taniguchi, Thien T. Tran, Ryo Suzuki, Daniel O. Espinoza, Yuji Yamamoto, Molly J. Ahrens, Andrew T. Dudley, Andrew W. Norris, Rohit N. Kulkarni, C. Ronald Kahn
Nature. Author manuscript; available in PMC 2009 Sep 17.
Published in final edited form as: Nature. 2008 Aug 21; 454(7207): 1000–1004. doi: 10.1038/nature07221
PMCID:
PMC2745972
AbstractArticlePDF–2.9M
11.
Impaired PGC-1α function in muscle in Huntington's disease
Rajnish K. Chaturvedi, Peter Adhihetty, Shubha Shukla, Thomas Hennessy, Noel Calingasan, Lichuan Yang, Anatoly Starkov, Mahmoud Kiaei, Milena Cannella, Jenny Sassone, Andrea Ciammola, Fernando Squitieri, M. Flint Beal
Hum Mol Genet. 2009 Aug 15; 18(16): 3048–3065. Published online 2009 May 21. doi: 10.1093/hmg/ddp243
PMCID:
PMC2733807
AbstractArticlePDF–1022K
12.
PGC-1α/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders
Sarika Srivastava, Francisca Diaz, Luisa Iommarini, Karine Aure, Anne Lombes, Carlos T. Moraes
Hum Mol Genet. 2009 May 15; 18(10): 1805–1812. Published online 2009 Mar 18. doi: 10.1093/hmg/ddp093
PMCID:
PMC2722224
AbstractArticlePDF–370K
13.
FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
Matthew J. Potthoff, Takeshi Inagaki, Santhosh Satapati, Xunshan Ding, Tianteng He, Regina Goetz, Moosa Mohammadi, Brian N. Finck, David J. Mangelsdorf, Steven A. Kliewer, Shawn C. Burgess
Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26): 10853–10858. Published online 2009 Jun 16. doi: 10.1073/pnas.0904187106
PMCID:
PMC2705613
AbstractArticlePDF–443K
14.
Rosiglitazone Treatment Prevents Mitochondrial Dysfunction in Mutant Huntingtin-expressing Cells: POSSIBLE ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ (PPARγ) IN THE PATHOGENESIS OF HUNTINGTON DISEASE
Rodrigo A. Quintanilla, Youngnam N. Jin, Karen Fuenzalida, Miguel Bronfman, Gail V. W. Johnson
J Biol Chem. 2008 Sep 12; 283(37): 25628–25637. doi: 10.1074/jbc.M804291200
PMCID:
PMC2533094
AbstractArticlePDF–610K
15.
Transcriptional coactivators PGC-1α and PGC-lβ control overlapping programs required for perinatal maturation of the heart
Ling Lai, Teresa C. Leone, Christoph Zechner, Paul J. Schaeffer, Sean M. Kelly, Daniel P. Flanagan, Denis M. Medeiros, Attila Kovacs, Daniel P. Kelly
Genes Dev. 2008 Jul 15; 22(14): 1948–1961. doi: 10.1101/gad.1661708
PMCID:
PMC2492740
AbstractArticlePDF–1.2M
16.
PGC-1α regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy
Christoph Handschin, Yvonne M. Kobayashi, Sherry Chin, Patrick Seale, Kevin P. Campbell, Bruce M. Spiegelman
Genes Dev. 2007 Apr 1; 21(7): 770–783. doi: 10.1101/gad.1525107
PMCID:
PMC1838529
AbstractArticlePDF–1023K
17.
PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
Marco Sandri, Jiandie Lin, Christoph Handschin, Wenli Yang, Zoltan P. Arany, Stewart H. Lecker, Alfred L. Goldberg, Bruce M. Spiegelman
Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44): 16260–16265. Published online 2006 Oct 19. doi: 10.1073/pnas.0607795103
PMCID:
PMC1637570
AbstractArticlePDF–2.1M
18.
PGC-1α controls hepatitis B virus through nutritional signals
Amir Shlomai, Nir Paran, Yosef Shaul
Proc Natl Acad Sci U S A. 2006 Oct 24; 103(43): 16003–16008. Published online 2006 Oct 16. doi: 10.1073/pnas.0607837103
PMCID:
PMC1635117
AbstractArticlePDF–928K
19.
Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1α transcription and mitochondrial biogenesis in muscle cells
Zhidan Wu, Xueming Huang, Yajun Feng, Christoph Handschin, Yan Feng, P. Scott Gullicksen, Olivia Bare, Mark Labow, Bruce Spiegelman, Susan C. Stevenson
Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39): 14379–14384. Published online 2006 Sep 15. doi: 10.1073/pnas.0606714103
PMCID:
PMC1569674
AbstractArticlePDF–1.2M
20.
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-γ coactivator 1α
Zoltan Arany, Mikhail Novikov, Sherry Chin, Yanhong Ma, Anthony Rosenzweig, Bruce M. Spiegelman
Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26): 10086–10091. Published online 2006 Jun 14. doi: 10.1073/pnas.0603615103
PMCID:
PMC1502510
AbstractArticlePDF–1.0M

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