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Select item 112293261.

Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function

Markéta Šoltysová, Jana Škerlová, Petr Pachl, Karel Škubník, Milan Fábry, Irena Sieglová, Martina Farolfi, Irina Grishkovskaya, Michal Babiak, Jiří Nováček, Libor Krásný, Pavlína Řezáčová

Nucleic Acids Res. 2024 Jul 8; 52(12): 7305–7320. Published online 2024 Jun 6. doi: 10.1093/nar/gkae434

PMCID:: PMC11229326

Abstract Article PDF–2.1M

Select item 111572722.

Fructose-1-kinase has pleiotropic roles in Escherichia coli

Chamitha Weeramange, Cindy Menjivar, Pierce T. O’Neil, Samir El Qaidi, Kelly S. Harrison, Sarah Meinhardt, Cole L. Bird, Shwetha Sreenivasan, Philip R. Hardwidge, Aron W. Fenton, P. Scott Hefty, Jeffrey L. Bose, Liskin Swint-Kruse

J Biol Chem. 2024 Jun; 300(6): 107352. Published online 2024 May 8. doi: 10.1016/j.jbc.2024.107352

PMCID:: PMC11157272

Abstract Article PDF–1.8M

Select item 110672283.

Metabolomics reveals high fructose-1,6-bisphosphate from fluoride-resistant Streptococcus mutans

Laikuan Zhu, Jiehang Li, Yueping Pan, Jing Huang, Hui Yao

BMC Microbiol. 2024; 24: 151. Published online 2024 May 3. doi: 10.1186/s12866-024-03310-8

PMCID:: PMC11067228

Abstract Article PDF–2.1M

Select item 99825764.

Nuclear Fructose‐1,6‐Bisphosphate Inhibits Tumor Growth and Sensitizes Chemotherapy by Targeting HMGB1

Yeyi Li, Yuan Fu, Yan Zhang, Bilian Duan, Yanli Zhao, Man Shang, Ying Cheng, Kai Zhang, Qiujing Yu, Ting Wang

Adv Sci (Weinh) 2023 Mar; 10(7): 2203528. Published online 2023 Jan 15. doi: 10.1002/advs.202203528

PMCID:: PMC9982576

Abstract Article PDF–4.6M

Select item 93514535.

Monitoring glycolytic dynamics in single cells using a fluorescent biosensor for fructose 1,6-bisphosphate

John N. Koberstein, Melissa L. Stewart, Chadwick B. Smith, Andrei I. Tarasov, Frances M. Ashcroft, Philip J. S. Stork, Richard H. Goodman

Proc Natl Acad Sci U S A. 2022 Aug 2; 119(31): e2204407119. Published online 2022 Jul 26. doi: 10.1073/pnas.2204407119

PMCID:: PMC9351453

Abstract Article PDF–1.5M

Select item 90372706.

The role of fructose 1,6-bisphosphate-mediated glycolysis/gluconeogenesis genes in cancer prognosis

Chien-Hsiu Li, Ming-Hsien Chan, Yu-Chan Chang

Aging (Albany NY) 2022 Apr 15; 14(7): 3233–3258. Published online 2022 Apr 11. doi: 10.18632/aging.204010

PMCID:: PMC9037270

Abstract Article PDF–3.1M

Select item 87949947.

PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease

Zongwei Zhang, Wei Liang, Qiang Luo, Hongtu Hu, Keju Yang, Jijia Hu, Zhaowei Chen, Jili Zhu, Jun Feng, Zijing Zhu, Qingjia Chi, Guohua Ding

Front Endocrinol (Lausanne) 2021; 12: 797025. Published online 2022 Jan 14. doi: 10.3389/fendo.2021.797025

PMCID:: PMC8794994

Abstract Article PDF–19M

Select item 87419448.

The effects of fructose diphosphate on routine coagulation tests in vitro

Tongqing Chen, Duan Chen, Lu Chen, Zhengxu Chen, Baolong Wang, Daoping Zhou

Sci Rep. 2022; 12: 304. Published online 2022 Jan 7. doi: 10.1038/s41598-021-04263-y

PMCID:: PMC8741944

Abstract Article PDF–1.1M

Select item 82854289.

Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development

Jianli He, Xun Shangguan, Wei Zhou, Ying Cao, Quan Zheng, Jun Tu, Gaolei Hu, Zi Liang, Cen Jiang, Liufu Deng, Shengdian Wang, Wen Yang, Yong Zuo, Jiao Ma, Rong Cai, Yalan Chen, Qiuju Fan, Baijun Dong, Wei Xue, Hongsheng Tan, Yitao Qi, Jianmin Gu, Bing Su, Y. Eugene Chin, Guoqiang Chen, Qi Wang, Tianshi Wang, Jinke Cheng

Nat Commun. 2021; 12: 4371. Published online 2021 Jul 16. doi: 10.1038/s41467-021-24619-2

PMCID:: PMC8285428

Abstract Article PDF–3.8M

Select item 820162010.

The phosphate moiety of phosphoenolpyruvate does NOT contribute to allosteric regulation of liver pyruvate kinase by fructose-1,6-bisphosphate

Benjamin M. Chappell, Aron W. Fenton

Arch Biochem Biophys. Author manuscript; available in PMC 2021 Nov 30.

Published in final edited form as: Arch Biochem Biophys. 2020 Nov 30; 695: 108633. Published online 2020 Oct 16. doi: 10.1016/j.abb.2020.108633

PMCID:: PMC8201620

Abstract Article PDF–980K

Select item 786726511.

Phosphofructokinases A and B from Mycobacterium tuberculosis Display Different Catalytic Properties and Allosteric Regulation

Jan Snášel, Iva Machová, Veronika Šolínová, Václav Kašička, Marcela Krečmerová, Iva Pichová

Int J Mol Sci. 2021 Feb; 22(3): 1483. Published online 2021 Feb 2. doi: 10.3390/ijms22031483

PMCID:: PMC7867265

Abstract Article PDF–2.8M

Select item 761185312.

Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly

Gea Cereghetti, Caroline Wilson-Zbinden, Vera M. Kissling, Maren Diether, Alexandra Arm, Haneul Yoo, Ilaria Piazza, Shady Saad, Paola Picotti, D. Allan Drummond, Uwe Sauer, Reinhard Dechant, Matthias Peter

Nat Cell Biol. Author manuscript; available in PMC 2022 Apr 6.

Published in final edited form as: Nat Cell Biol. 2021 Oct 1; 23(10): 1085–1094. Published online 2021 Oct 6. doi: 10.1038/s41556-021-00760-4

PMCID:: PMC7611853

Abstract Article PDF–3.8M

Select item 759396813.

Aberrant Intracellular pH Regulation Limiting Glyceraldehyde-3-Phosphate Dehydrogenase Activity in the Glucose-Sensitive Yeast tps1Δ Mutant

Frederik Van Leemputte, Ward Vanthienen, Stefanie Wijnants, Griet Van Zeebroeck, Johan M. Thevelein

mBio. 2020 Sep-Oct; 11(5): e02199-20. Published online 2020 Oct 27. doi: 10.1128/mBio.02199-20

PMCID:: PMC7593968

Abstract Article PDF–1.6M

Select item 692070314.

Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor

Francisca Monteiro, Georg Hubmann, Vakil Takhaveev, Silke R Vedelaar, Justin Norder, Johan Hekelaar, Joana Saldida, Athanasios Litsios, Hein J Wijma, Alexander Schmidt, Matthias Heinemann

Mol Syst Biol. 2019 Dec; 15(12): e9071. Published online 2019 Dec 19. doi: 10.15252/msb.20199071

PMCID:: PMC6920703

Abstract Article PDF–1.7M

Select item 686128615.

Functional tunability from a distance: Rheostat positions influence allosteric coupling between two distant binding sites

Tiffany Wu, Liskin Swint-Kruse, Aron W. Fenton

Sci Rep. 2019; 9: 16957. Published online 2019 Nov 18. doi: 10.1038/s41598-019-53464-z

PMCID:: PMC6861286

Abstract Article PDF–1.9M

Select item 681429516.

Distinctive regulatory properties of pyruvate kinase 1 from Aedes aegypti mosquitoes

Natthida Petchampai, Claribel Murillo-Solano, Jun Isoe, Juan C. Pizarro, Patricia Y. Scaraffia

Insect Biochem Mol Biol. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Insect Biochem Mol Biol. 2019 Jan; 104: 82–90. Published online 2018 Dec 19. doi: 10.1016/j.ibmb.2018.12.010

PMCID:: PMC6814295

Abstract Article PDF–2.1M

Select item 678751317.

Beta‐elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation

Yanhong Pan, Wei Wang, Shuai Huang, Wenting Ni, Zhonghong Wei, Yuzhu Cao, Suyun Yu, Qi Jia, Yuanyuan Wu, Chuan Chai, Qian Zheng, Lei Zhang, Aiyun Wang, Zhiguang Sun, Shile Huang, Shijun Wang, Wenxing Chen, Yin Lu

J Cell Mol Med. 2019 Oct; 23(10): 6846–6858. Published online 2019 Jul 25. doi: 10.1111/jcmm.14568

PMCID:: PMC6787513

Abstract Article PDF–2.9M

Select item 673863318.

Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts

Henrique Bregolin Dias, Jarbas Rodrigues de Oliveira, Márcio Vinícius Fagundes Donadio, Shioko Kimura

PLoS One. 2019; 14(9): e0222202. Published online 2019 Sep 11. doi: 10.1371/journal.pone.0222202

PMCID:: PMC6738633

Abstract Article PDF–3.3M

Select item 667338319.

Fructose-1,6-Bisphosphate Has Anticonvulsant Activity in Models of Acute Seizures in Adult Rats

Xiao-Yuan Lian, Firdous A. Khan, Janet L. Stringer

J Neurosci. 2007 Oct 31; 27(44): 12007–12011. doi: 10.1523/JNEUROSCI.3163-07.2007

PMCID:: PMC6673383

Abstract Article PDF–468K

Select item 663699820.

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation

Jamie A Macpherson, Alina Theisen, Laura Masino, Louise Fets, Paul C Driscoll, Vesela Encheva, Ambrosius P Snijders, Stephen R Martin, Jens Kleinjung, Perdita E Barran, Franca Fraternali, Dimitrios Anastasiou

eLife. 2019; 8: e45068. Published online 2019 Jul 2. doi: 10.7554/eLife.45068