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Items: 1 to 20 of 5394

1.
Distinct subcellular localization of tau and alpha-synuclein in lewy body disease
D. Luke Fischer, Marissa Menard, Omar Z. Abdelaziz, Nicholas M. Kanaan, Virginia G. Cobbs, Richard E. Kennedy, Geidy E. Serrano, Thomas G. Beach, Laura A. Volpicelli-Daley
Acta Neuropathol Commun. 2025; 13: 14. Published online 2025 Jan 21. doi: 10.1186/s40478-024-01913-w
PMCID:
PMC11752823
ArticlePDF–20M
2.
Recursive seed amplification detects distinct α-synuclein strains in cerebrospinal fluid of patients with Parkinson’s disease
Stefan Bräuer, Iñaki Schniewind, Elisabeth Dinter, Björn H. Falkenburger
Acta Neuropathol Commun. 2025; 13: 13. Published online 2025 Jan 20. doi: 10.1186/s40478-024-01923-8
PMCID:
PMC11749544
ArticlePDF–6.1M
3.
Lipidic folding pathway of α-Synuclein via a toxic oligomer
Vrinda Sant, Dirk Matthes, Hisham Mazal, Leif Antonschmidt, Franz Wieser, Kumar T. Movellan, Kai Xue, Evgeny Nimerovsky, Marianna Stampolaki, Magdeline Nathan, Dietmar Riedel, Stefan Becker, Vahid Sandoghdar, Bert L. de Groot, Christian Griesinger, Loren B. Andreas
Nat Commun. 2025; 16: 760. Published online 2025 Jan 17. doi: 10.1038/s41467-025-55849-3
PMCID:
PMC11742675
ArticlePDF–2.2M
4.
Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform
Dorothea Böken, Zengjie Xia, Jeff Y. L. Lam, Emre Fertan, Yunzhao Wu, Elizabeth A. English, Juraj Konc, Florence Layburn, Gonçalo J. L. Bernardes, Henrik Zetterberg, Matthew R. Cheetham, David Klenerman
Anal Chem. 2025 Jan 14; 97(1): 290–299. Published online 2024 Dec 24. doi: 10.1021/acs.analchem.4c04188
PMCID:
PMC11740166
ArticlePDF–3.0M
5.
Peripheral proteinopathy in neurodegenerative diseases
Bin Xu, Xia Lei, Ying Yang, Jiayi Yu, Jun Chen, Zhi Xu, Keqiang Ye, Jing Zhang
Transl Neurodegener. 2025; 14: 2. Published online 2025 Jan 16. doi: 10.1186/s40035-024-00461-6
PMCID:
PMC11737199
ArticlePDF–1.2M
6.
A nanoparticle-based wireless deep brain stimulation system that reverses Parkinson’s disease
Junguang Wu, Xuejing Cui, Lin Bao, Guanyu Liu, Xiaoyu Wang, Chunying Chen
Sci Adv. 2025 Jan 17; 11(3): eado4927. Published online 2025 Jan 15. doi: 10.1126/sciadv.ado4927
PMCID:
PMC11734722
ArticlePDF–13M
7.
Spiral volumetric optoacoustic tomography of reduced oxygen saturation in the spinal cord of M83 mouse model of Parkinson’s disease
Benjamin F. Combes, Sandeep Kumar Kalva, Pierre-Louis Benveniste, Agathe Tournant, Man Hoi Law, Joshua Newton, Maik Krüger, Rebecca Z. Weber, Inês Dias, Daniela Noain, Xose Luis Dean-Ben, Uwe Konietzko, Christian R. Baumann, Per-Göran Gillberg, Christoph Hock, Roger M. Nitsch, Julien Cohen-Adad, Daniel Razansky, Ruiqing Ni
Eur J Nucl Med Mol Imaging. 2025; 52(2): 427–443. Published online 2024 Oct 9. doi: 10.1007/s00259-024-06938-w
PMCID:
PMC11732882
ArticlePDF–9.7M
8.
Iron(ing) out parkinsonisms: The interplay of proteinopathy and ferroptosis in Parkinson's disease and tau-related parkinsonisms
Maria João da Costa Caiado, Amalia M. Dolga, Wilfred F.A. den Dunnen
Redox Biol. 2025 Feb; 79: 103478. Published online 2024 Dec 19. doi: 10.1016/j.redox.2024.103478
PMCID:
PMC11732237
ArticlePDF–4.1M
9.
Cryo‐EM structure of a novel α‐synuclein filament subtype from multiple system atrophy
Nicholas L. Yan, Francisco Candido, Eric Tse, Arthur A. Melo, Stanley B. Prusiner, Daniel A. Mordes, Daniel R. Southworth, Nick A. Paras, Gregory E. Merz
FEBS Lett. 2025 Jan; 599(1): 33–40. Published online 2024 Nov 7. doi: 10.1002/1873-3468.15048
PMCID:
PMC11726156
ArticlePDF–1.5M
10.
HDAC6 inhibitor-loaded brain-targeted nanocarrier-mediated neuroprotection in methamphetamine-driven Parkinson's disease
Khang-Yen Pham, Shristi Khanal, Ganesh Bohara, Nikesh Rimal, Sang-Hoon Song, Thoa Thi Kim Nguyen, In-Sun Hong, Jinkyung Cho, Jong-Sun Kang, Sooyeun Lee, Dong-Young Choi, Simmyung Yook
Redox Biol. 2025 Feb; 79: 103457. Published online 2024 Dec 5. doi: 10.1016/j.redox.2024.103457
PMCID:
PMC11722933
ArticlePDF–25M
11.
The α-Synuclein Seeding Amplification Assay for Parkinson’s Disease
Ling-Xiao Yi, Eng King Tan, Zhi Dong Zhou
Int J Mol Sci. 2025 Jan; 26(1): 389. Published online 2025 Jan 4. doi: 10.3390/ijms26010389
PMCID:
PMC11720040
ArticlePDF–274K
12.
Angiotensin-(1-7) relieves behavioral defects and α-synuclein expression through NEAT1/miR-153-3p axis in Parkinson’s disease
Qing Gao, Xiaoyuan Li, Ting Huang, Li Gao, Siyu Wang, Yang Deng, Feng Wang, Xue Xue, Rui Duan
Aging (Albany NY) 2024 Nov 30; 16(21): 13304–13322. Published online 2024 Oct 17. doi: 10.18632/aging.206028
PMCID:
PMC11719108
ArticlePDF–2.7M
13.
Human Microglia–Like Cells Differentiated from Monocytes with GM-CSF and IL-34 Show Phagocytosis of α-Synuclein Aggregates and C/EBPβ-Dependent Proinflammatory Activation
Andrea Llaves-López, Elia Micoli, Carla Belmonte-Mateos, Gerard Aguilar, Clara Alba, Anais Marsal, Marta Pulido-Salgado, Neus Rabaneda-Lombarte, Carme Solà, Joan Serratosa, Jose M. Vidal-Taboada, Josep Saura
Mol Neurobiol. 2025; 62(1): 756–772. Published online 2024 Jun 20. doi: 10.1007/s12035-024-04289-z
PMCID:
PMC11711251
ArticlePDF–1.8M
14.
Are oligodendrocytes bystanders or drivers of Parkinson’s disease pathology?
José María Salazar Campos, Lena F. Burbulla, Sarah Jäkel
PLoS Biol. 2025 Jan; 23(1): e3002977. Published online 2025 Jan 8. doi: 10.1371/journal.pbio.3002977
PMCID:
PMC11709285
ArticlePDF–1.4M
15.
Distinct transcriptional alterations distinguish Lewy body disease from Alzheimer’s disease
Kimberly C Olney, Benjamin E Rabichow, Aleksandra M Wojtas, Michael DeTure, Pamela J McLean, Dennis W Dickson, Rui Chang, Owen A Ross, John D Fryer
Brain. 2025 Jan; 148(1): 69–88. Published online 2024 Jun 25. doi: 10.1093/brain/awae202
PMCID:
PMC11706328
ArticlePDF–10M
16.
Positron emission tomography tracers for synucleinopathies
Jie Xiang, Zhentao Zhang, Shengxi Wu, Keqiang Ye
Mol Neurodegener. 2025; 20: 1. Published online 2025 Jan 5. doi: 10.1186/s13024-024-00787-9
PMCID:
PMC11702101
ArticlePDF–1.2M
17.
Young rat microbiota extracts strongly inhibit fibrillation of α-synuclein and protect neuroblastoma cells and zebrafish against α-synuclein toxicity
Mohaddeseh Ghorbani Shiraz, Janni Nielsen, Jeremias Widmann, Ka Hang Karen Chung, Thomas Paul Davis, Casper Rasmussen, Carsten Scavenius, Jan J. Enghild, Camille Martin-Gallausiaux, Yogesh Singh, Ibrahim Javed, Daniel E. Otzen
Mol Cells. 2025 Jan; 48(1): 100161. Published online 2024 Nov 26. doi: 10.1016/j.mocell.2024.100161
PMCID:
PMC11699742
ArticlePDF–7.8M
18.
Site-specific seeding of Lewy pathology induces distinct pre-motor cellular and dendritic vulnerabilities in the cortex
Hammad F. Khan, Sayan Dutta, Alicia N. Scott, Shulan Xiao, Saumitra Yadav, Xiaoling Chen, Uma K. Aryal, Tamara L. Kinzer-Ursem, Jean-Christophe Rochet, Krishna Jayant
Nat Commun. 2024; 15: 10775. Published online 2024 Dec 30. doi: 10.1038/s41467-024-54945-0
PMCID:
PMC11685769
ArticlePDF–7.1M
19.
Parkin通过介导PINK 1/Parkin线粒体自噬信号通路加速小鼠帕金森病发展及加剧神经炎症发生
姜 诚诚, 李 洋洋, 段 可欣, 詹 婷婷, 陈 子龙, 王 永雪, 赵 蕊, 马 彩云, 郭 俣, 刘 长青
Nan Fang Yi Ke Da Xue Xue Bao. 2024 Dec 20; 44(12): 2359–2366. Chinese. doi: 10.12122/j.issn.1673-4254.2024.12.11
PMCID:
PMC11683357
ArticlePDF–3.7M
20.
The Search for a Universal Treatment for Defined and Mixed Pathology Neurodegenerative Diseases
Danton H. O’Day
Int J Mol Sci. 2024 Dec; 25(24): 13424. Published online 2024 Dec 14. doi: 10.3390/ijms252413424
PMCID:
PMC11678063
ArticlePDF–2.4M

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