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Items: 1 to 20 of 38

1.
Leonurine Exerts Anti-Inflammatory Effects in Lipopolysaccharide (LPS)-Induced Endometritis by Modulating Mouse JAK-STAT/PI3K-Akt/PPAR Signaling Pathways
Yongbin Shao, Yan Luo, Yaoqiang Sun, Jingbo Jiang, Zhiyuan Li, Zhen Wang, Mengmeng Wang, Xinli Gu
Genes (Basel) 2024 Jul; 15(7): 857. Published online 2024 Jun 29. doi: 10.3390/genes15070857
PMCID:
PMC11276431
AbstractArticlePDF–3.2M
2.
Assessment of the Effect of Leonurine Hydrochloride in a Mouse Model of PCOS by Gene Expression Profiling
Mengmeng Wang, Li Yang, Guojie Sun, Yongbin Shao, Yuran Liu, Huiying Yang, Yan Wang, Mengyuan Zhang, Yunxia Shang, Xinli Gu
Genes (Basel) 2024 Apr; 15(4): 507. Published online 2024 Apr 18. doi: 10.3390/genes15040507
PMCID:
PMC11050333
AbstractArticlePDF–5.9M
3.
Leonurine pretreatment protects the heart from myocardial ischemia-reperfusion injury
Huiping Lu, Jingru Gong, Tongtong Zhang, Zhe Jiang, Wenmin Dong, Jing Dai, Fenfen Ma
Exp Biol Med (Maywood) 2023 Sep; 248(18): 1566–1578. Published online 2023 Oct 24. doi: 10.1177/15353702231198066
PMCID:
PMC10676124
AbstractArticlePDF–11M
4.
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis
Pan Meng, Xi Zhang, Dandan Li, Hui Yang, Xiaoyuan Lin, Hongqing Zhao, Ping Li, Yuhong Wang, Xiaoye Wang, Jinwen Ge
Neural Plast. 2023; 2023: 1455634. Published online 2023 Jan 7. doi: 10.1155/2023/1455634
PMCID:
PMC9840550
AbstractArticlePDF–2.4M
5.
Inhibitory Effects of Standardized Leonurus japonicus Extract and Its Bioactive Leonurine on TNF-α-Induced Muscle Atrophy in L6 Myotubes
Jiyeon Lee, Changhee Kim, Hyerin Lee,, Jae-Kwan Hwang
J Microbiol Biotechnol. 2020 Dec 28; 30(12): 1896–1904. Published online 2020 Jun 19. doi: 10.4014/jmb.2005.05023
PMCID:
PMC9728349
AbstractArticlePDF–4.6M
6.
Leonurine inhibits cardiomyocyte pyroptosis to attenuate cardiac fibrosis via the TGF-β/Smad2 signalling pathway
Zhaoyi Li, Keyuan Chen, Yi Zhun Zhu
PLoS One. 2022; 17(11): e0275258. Published online 2022 Nov 3. doi: 10.1371/journal.pone.0275258
PMCID:
PMC9632889
AbstractArticlePDF–3.2M
7.
Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver–Cardiac Crosstalk Metabolomics Study
Weiwei Rong, Jiejia Li, Dingyi Pan, Qinbei Zhou, Yexuan Zhang, Qianxing Lu, Liyun Wang, Andong Wang, Yizhun Zhu, Qing Zhu
Biomolecules. 2022 Oct; 12(10): 1512. Published online 2022 Oct 19. doi: 10.3390/biom12101512
PMCID:
PMC9599793
AbstractArticlePDF–2.4M
8.
Leonurine Reduces Oxidative Stress and Provides Neuroprotection against Ischemic Injury via Modulating Oxidative and NO/NOS Pathway
Ziteng Deng, Jiao Li, Xiaoquan Tang, Dan Li, Yazhou Wang, Shengxi Wu, Kai Fan, Yunfei Ma
Int J Mol Sci. 2022 Sep; 23(17): 10188. Published online 2022 Sep 5. doi: 10.3390/ijms231710188
PMCID:
PMC9456230
AbstractArticlePDF–4.0M
9.
SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals
Yi-Kong Lin, Yun-Yun Li, Yue Li, Da-Jin Li, Xiao-Lin Wang, Li Wang, Min Yu, Yi-Zhun Zhu, Jia-Jing Cheng, Mei-Rong Du
Front Endocrinol (Lausanne) 2022; 13: 858176. Published online 2022 Jun 15. doi: 10.3389/fendo.2022.858176
PMCID:
PMC9245568
AbstractArticlePDF–12M
10.
Leonurine Protects Bone Mesenchymal Stem Cells from Oxidative Stress by Activating Mitophagy through PI3K/Akt/mTOR Pathway
Bingkun Zhao, Qian Peng, Dan Wang, Rong Zhou, Raorao Wang, Yizhun Zhu, Shengcai Qi
Cells. 2022 Jun; 11(11): 1724. Published online 2022 May 24. doi: 10.3390/cells11111724
PMCID:
PMC9179429
AbstractArticlePDF–5.5M
11.
SCM-198 Alleviates Endometriosis by Suppressing Estrogen-ERα mediated Differentiation and Function of CD4+CD25+ Regulatory T Cells
Yun-yun Li, Yi-kong Lin, Yue Li, Xin-hua Liu, Da-jin Li, Xiao-lin Wang, Li Wang, Yi-zhun Zhu, Min Yu, Mei-rong Du
Int J Biol Sci. 2022; 18(5): 1961–1973. Published online 2022 Feb 21. doi: 10.7150/ijbs.68224
PMCID:
PMC8935231
AbstractArticlePDF–3.5M
12.
Oxidative Injury in Ischemic Stroke: A Focus on NADPH Oxidase 4
Ganglei Li, Changsheng Ye, Yu Zhu, Tiesong Zhang, Jun Gu, Jianwei Pan, Feng Wang, Fan Wu, Kaiyuan Huang, Kangli Xu, Xiaomin Wu, Jian Shen
Oxid Med Cell Longev. 2022; 2022: 1148874. Published online 2022 Feb 3. doi: 10.1155/2022/1148874
PMCID:
PMC8831073
AbstractArticlePDF–1.1M
13.
Alkaloid leonurine exerts anti‐inflammatory effects via modulating MST1 expression in trophoblast cells
Fang Zong, Yingzi Zhao
Immun Inflamm Dis. 2021 Dec; 9(4): 1439–1446. Published online 2021 Jul 28. doi: 10.1002/iid3.493
PMCID:
PMC8589353
AbstractArticlePDF–1.7M
14.
Leonurine affected homocysteine‐methionine metabolism based on metabolomics and gut microbiota studies of clinical trial samples
Junyi Liao, Rinkiko Suguro, Xia Zhao, Yue Yu, Yimin Cui, Yi Zhun Zhu
Clin Transl Med. 2021 Oct; 11(10): e535. Published online 2021 Oct 12. doi: 10.1002/ctm2.535
PMCID:
PMC8506629
ArticlePDF–1.3M
15.
Leonurine Ameliorates Oxidative Stress and Insufficient Angiogenesis by Regulating the PI3K/Akt-eNOS Signaling Pathway in H2O2-Induced HUVECs
Li Liao, Lihong Gong, Mengting Zhou, Xinyan Xue, Yunxia Li, Cheng Peng
Oxid Med Cell Longev. 2021; 2021: 9919466. Published online 2021 Aug 3. doi: 10.1155/2021/9919466
PMCID:
PMC8357476
AbstractArticlePDF–2.6M
16.
Leonurine, a potential drug for the treatment of cardiovascular system and central nervous system diseases
Lu Huang, Ding‐Qiao Xu, Yan‐Yan Chen, Shi‐Jun Yue, Yu‐Ping Tang
Brain Behav. 2021 Feb; 11(2): e01995. Published online 2020 Dec 10. doi: 10.1002/brb3.1995
PMCID:
PMC7882174
AbstractArticlePDF–1.0M
17.
Leonurine Regulates Treg/Th17 Balance to Attenuate Rheumatoid Arthritis Through Inhibition of TAZ Expression
Yan-Yi Du, Zhi-Xin Chen, Min-Ying Liu, Qing-Ping Liu, Chang-Song Lin, Cong-Qiu Chu, Qiang Xu
Front Immunol. 2020; 11: 556526. Published online 2020 Oct 7. doi: 10.3389/fimmu.2020.556526
PMCID:
PMC7575723
AbstractArticlePDF–2.2M
18.
Leonurine Promotes Cisplatin Sensitivity in Human Cervical Cancer Cells Through Increasing Apoptosis and Inhibiting Drug-Resistant Proteins
Min Lin, Chunyu Pan, Wenbin Xu, Jingwei Li, Xueqiong Zhu
Drug Des Devel Ther. 2020; 14: 1885–1895. Published online 2020 May 15. doi: 10.2147/DDDT.S252112
PMCID:
PMC7237110
AbstractArticlePDF–7.5M
19.
CYP2A13 Acts as the Main Metabolic CYP450s Enzyme for Activating Leonurine in Human Bronchial Epithelial Cells
Ting Xu, Xuxu Li, Tian Leng, Tianchi Zhuang, Yan Sun, Yajun Tang, Li Wang, Muyi Yang, Minghui Ji
Med Sci Monit. 2020; 26: e922149-1–e922149-7. Prepublished online 2020 Feb 17. Published online 2020 Apr 14. doi: 10.12659/MSM.922149
PMCID:
PMC7174896
AbstractArticlePDF–599K
20.
The Guanidine Pseudoalkaloids 10-Methoxy-Leonurine and Leonurine Act as Competitive Inhibitors of Tyrosinase
Jang Hoon Kim, Hyun Hee Leem, Ga Young Lee
Biomolecules. 2020 Feb; 10(2): 174. Published online 2020 Jan 23. doi: 10.3390/biom10020174
PMCID:
PMC7072302
AbstractArticlePDF–1.2M

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