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Select item 117737311.

Functions of thyroid hormone signaling in regulating melanophore, iridophore, erythrophore, and pigment pattern formation in spotted scat (Scatophagus argus)

Yongguan Liao, Tong Han, Dongneng Jiang, Chunhua Zhu, Gang Shi, GuangLi Li, Hongjuan Shi

BMC Genomics. 2025; 26: 79. Published online 2025 Jan 27. doi: 10.1186/s12864-025-11286-6

PMCID:: PMC11773731

Article PDF–12M

Select item 117109242.

Contents of sensitising rubber accelerators in disposable rubber gloves: A Copenhagen market survey

Christoffer Kursawe Larsen, Jakob F. B. Schwensen, Claus Zachariae, Cecilia Svedman, Jeanne D. Johansen, Ola Bergendorff

Contact Dermatitis. 2025 Feb; 92(2): 131–136. Published online 2024 Oct 5. doi: 10.1111/cod.14709

PMCID:: PMC11710924

Article PDF–1.2M

Select item 115875133.

Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics

Susantha K. Ganegamage, Taiwo A. Ademoye, Henika Patel, Heba Alnakhala, Arati Tripathi, Cuong Calvin Duc Nguyen, Khai Pham, Germán Plascencia-Villa, Xiongwei Zhu, George Perry, Shiliang Tian, Ulf Dettmer, Cristian Lasagna-Reeves, Jessica S. Fortin

ACS Chem Neurosci. 2024 Nov 6; 15(21): 3915–3931. Published online 2024 Oct 22. doi: 10.1021/acschemneuro.4c00282

PMCID:: PMC11587513

Article PDF–13M

Select item 115443974.

Endoplasmic reticulum stress induces renal fibrosis in high‑fat diet mice via the TGF‑β/SMAD pathway

Zhidan Mu, Bin Li, Mingyang Chen, Chen Liang, Wei Gu, Juan Su

Mol Med Rep. 2024 Dec; 30(6): 235. Published online 2024 Oct 14. doi: 10.3892/mmr.2024.13360

PMCID:: PMC11544397

Article PDF–10M

Select item 114428015.

Defective regulation of the eIF2-eIF2B translational axis underlies depressive-like behavior in mice and correlates with major depressive disorder in humans

Alinny R. Isaac, Mariana G. Chauvet, Ricardo Lima-Filho, Beatriz de A. Wagner, Bruno G. Caroli, Renata E. P. Leite, Claudia K. Suemoto, Paula Villela Nunes, Fernanda G. De Felice, Sergio T. Ferreira, Mychael V. Lourenco

Transl Psychiatry. 2024; 14: 397. Published online 2024 Oct 1. doi: 10.1038/s41398-024-03128-y

PMCID:: PMC11442801

Article PDF–1.2M

Select item 113994066.

Thiourea and arginine synergistically preserve redox homeostasis and ionic balance for alleviating salinity stress in wheat

Jingkun Li, Li Xu, Peng Xuan, Zhixiang Tian, Runqiang Liu

Sci Rep. 2024; 14: 21375. Published online 2024 Sep 13. doi: 10.1038/s41598-024-72614-6

PMCID:: PMC11399406

Article PDF–4.0M

Select item 113965497.

In Vitro Cytotoxic Potential and In Vivo Antitumor Effects of NOS/PDK-Inhibitor T1084

Marina Filimonova, Anna Shitova, Ljudmila Shevchenko, Olga Soldatova, Valentina Surinova, Vitaly Rybachuk, Alexander Kosachenko, Kirill Nikolaev, Irina Volkova, Grigory Demyashkin, Tatjana P. Stanojkovic, Zeljko Zizak, Sergey Ivanov, Petr Shegay, Andrey Kaprin, Alexander Filimonov

Int J Mol Sci. 2024 Sep; 25(17): 9711. Published online 2024 Sep 8. doi: 10.3390/ijms25179711

PMCID:: PMC11396549

Article PDF–9.6M

Select item 113947428.

Discovery of Indole–Thiourea Derivatives as Tyrosinase Inhibitors: Synthesis, Biological Evaluation, Kinetic Studies, and In Silico Analysis

Yang Xu, Xuhui Liang, Chang-Gu Hyun

Int J Mol Sci. 2024 Sep; 25(17): 9636. Published online 2024 Sep 5. doi: 10.3390/ijms25179636

PMCID:: PMC11394742

Article PDF–4.9M

Select item 113286039.

Design, synthesis, and biological evaluation of (thio)urea derivatives as potent Escherichia coli β-glucuronidase inhibitors

Keren Xu, Leyi Ying, Titi Ying, Qihao Wu, Lin Du, Yanlei Yu, Youmin Ying, Bin Wei, Hong Wang, Zhikun Yang

J Enzyme Inhib Med Chem. 2024; 39(1): 2387415. Published online 2024 Aug 14. doi: 10.1080/14756366.2024.2387415

PMCID:: PMC11328603

Article PDF–1.2M

Select item 1131412910.

Synthesis, Computational Study, and In Vitro α-Glucosidase Inhibitory Action of Thiourea Derivatives Based on 3-Aminopyridin-2(1H)-Ones

Zarina Shulgau, Irina Palamarchuk, Shynggys Sergazy, Assel Urazbayeva, Alexander Gulyayev, Yerlan Ramankulov, Ivan Kulakov

Molecules. 2024 Aug; 29(15): 3627. Published online 2024 Jul 31. doi: 10.3390/molecules29153627

PMCID:: PMC11314129

Article PDF–4.4M

Select item 1123704711.

Mitigating drought-induced oxidative stress in wheat (Triticum aestivum L.) through foliar application of sulfhydryl thiourea

Nazia Ishfaq, Ejaz Ahmad Waraich, Muhammad Ahmad, Saddam Hussain, Usman Zulfiqar, Kaleem Ul Din, Arslan Haider, Jean Wan Hong Yong, Syed Muhammad Hassan Askri, Hayssam M. Ali

Sci Rep. 2024; 14: 15985. Published online 2024 Jul 10. doi: 10.1038/s41598-024-66506-y

PMCID:: PMC11237047

Article PDF–2.1M

Select item 1120654912.

Design and Synthesis of Thiourea-Conjugating Organic Arsenic D-Glucose with Anticancer Activities

Boqiao Fu, Wenxuan Liu, Yufeng Wang, Guorui Li, Yingsha Wang, Xinyuan Huang, Hongan Shi, Caiqin Qin

Molecules. 2024 Jun; 29(12): 2850. Published online 2024 Jun 14. doi: 10.3390/molecules29122850

PMCID:: PMC11206549

Article PDF–2.0M

Select item 1113341013.

Thiourea improves yield and quality traits of Brassica napus L. by upregulating the antioxidant defense system under high temperature stress

Muhammad Ahmad, Ejaz Ahmad Waraich, Usman Zulfiqar, Jean Wan Hong Yong, Muhammad Ishfaq, Kaleem ul din, Aman Ullah, Adeel Abbas, Masood Iqbal Awan, Ihab Mohamed Moussa, Mohamed S. Elshikh

Sci Rep. 2024; 14: 12195. Published online 2024 May 28. doi: 10.1038/s41598-024-62257-y

PMCID:: PMC11133410

Article PDF–3.1M

Select item 1108061314.

Lysosomal BK channels facilitate silica-induced inflammation in macrophages

Rebekah L. Kendall, Andrij Holian

Inhal Toxicol. Author manuscript; available in PMC 2025 Jan 23.

Published in final edited form as: Inhal Toxicol. 2024 Jan; 36(1): 31–43. Published online 2024 Jan 23. doi: 10.1080/08958378.2024.2305112

PMCID:: PMC11080613

Article PDF–943K

Select item 1107894515.

A green, facile, and practical preparation of capsaicin derivatives with thiourea structure

Lina Chen, Zhenhua Gao, Ye Zhang, Xiandong Dai, Fanhua Meng, Yongbiao Guo

Sci Rep. 2024; 14: 10576. Published online 2024 May 8. doi: 10.1038/s41598-024-61014-5

PMCID:: PMC11078945

Article PDF–1.3M

Select item 1102757216.

Salubrinal promotes phospho-eIF2α-dependent activation of UPR leading to autophagy-mediated attenuation of iron-induced insulin resistance

Khang Nguyen, Jialing Tang, Sungji Cho, Fan Ying, Hye Kyoung Sung, James Wonsuk Jahng, Kostas Pantopoulos, Gary Sweeney

Mol Metab. 2024 May; 83: 101921. Published online 2024 Mar 26. doi: 10.1016/j.molmet.2024.101921

PMCID:: PMC11027572

Article PDF–2.3M

Select item 1101301417.

Design, Synthesis, Computational Studies, and Anti-Proliferative Evaluation of Novel Ethacrynic Acid Derivatives Containing Nitrogen Heterocycle, Urea, and Thiourea Moieties as Anticancer Agents

Abdelmoula El Abbouchi, Khaoula Mkhayar, Souad Elkhattabi, Nabil El Brahmi, Marie-Aude Hiebel, Jérôme Bignon, Gérald Guillaumet, Franck Suzenet, Saïd El Kazzouli

Molecules. 2024 Apr; 29(7): 1437. Published online 2024 Mar 23. doi: 10.3390/molecules29071437

PMCID:: PMC11013014

Article PDF–3.7M

Select item 1101241718.

Inhibition of the Sodium–Calcium Exchanger Reverse Mode Activity Reduces Alcohol Consumption in Rats

Gleice Kelli Silva-Cardoso, Prosper N’Gouemo

Int J Mol Sci. 2024 Apr; 25(7): 4132. Published online 2024 Apr 8. doi: 10.3390/ijms25074132

PMCID:: PMC11012417

Article PDF–3.0M

Select item 1095474019.

Structural basis of ligand recognition and design of antihistamines targeting histamine H₄ receptor

Ruixue Xia, Shuang Shi, Zhenmei Xu, Henry F. Vischer, Albert D. Windhorst, Yu Qian, Yaning Duan, Jiale Liang, Kai Chen, Anqi Zhang, Changyou Guo, Rob Leurs, Yuanzheng He

Nat Commun. 2024; 15: 2493. Published online 2024 Mar 20. doi: 10.1038/s41467-024-46840-5