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Select item 113194741.

Malonate given at reperfusion prevents post-myocardial infarction heart failure by decreasing ischemia/reperfusion injury

Jiro Abe, Ana Vujic, Hiran A. Prag, Michael P. Murphy, Thomas Krieg

Basic Res Cardiol. 2024; 119(4): 691–697. Published online 2024 Jun 12. doi: 10.1007/s00395-024-01063-z

PMCID:: PMC11319474

Abstract Article PDF–913K

Select item 110815212.

Addition of sodium malonate alters the morphology and increases the critical flux during tangential flow filtration of precipitated immunoglobulins

Ali Behboudi, Mirko Minervini, Zachary S. Badinger, William W. Haddad, Andrew L. Zydney

Protein Sci. 2024 Jun; 33(6): e5010. Published online 2024 May 9. doi: 10.1002/pro.5010

PMCID:: PMC11081521

Abstract Article PDF–13M

Select item 110664673.

A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding

Annabel Sorby-Adams, Tracy A. Prime, Jan Lj Miljkovic, Hiran A. Prag, Thomas Krieg, Michael P. Murphy

Redox Biol. 2024 Jun; 72: 103161. Published online 2024 Apr 24. doi: 10.1016/j.redox.2024.103161

Correction in:: Redox Biol. 2024 Aug; 74: 103210.

PMCID:: PMC11066467

Abstract Article PDF–4.2M

Select item 110502514.

Long-Term Protective Effects of Succinate Dehydrogenase Inhibition during Reperfusion with Malonate on Post-Infarction Left Ventricular Scar and Remodeling in Mice

Laura Valls-Lacalle, Marta Consegal, Freddy G. Ganse, Laia Yáñez-Bisbe, Javier Pastor, Marisol Ruiz-Meana, Javier Inserte, Begoña Benito, Ignacio Ferreira-González, Antonio Rodríguez-Sinovas

Int J Mol Sci. 2024 Apr; 25(8): 4366. Published online 2024 Apr 15. doi: 10.3390/ijms25084366

PMCID:: PMC11050251

Abstract Article PDF–4.7M

Select item 107174875.

Tolfenamic acid inhibits ROS-generating oxidase Nox1-regulated p53 activity in intrastriatal injection of malonic acid rats

Xin Yang, Heling Zhang, Tong Qu, Yi Wang, Yongxian Zhong, Yuchen Yan, Xuefei Ji, Tiayan Chi, Peng Liu, Libo Zou

J Physiol Sci. 2022; 72: 15. Published online 2022 Jul 18. doi: 10.1186/s12576-022-00842-4

PMCID:: PMC10717487

Abstract Article PDF–3.2M

Select item 105741016.

The Formulation and Evaluation of Deep Eutectic Vehicles for the Topical Delivery of Azelaic Acid for Acne Treatment

Dhari K. Luhaibi, Hiba H. Mohammed Ali, Israa Al-Ani, Naeem Shalan, Faisal Al-Akayleh, Mayyas Al-Remawi, Jehad Nasereddin, Nidal A. Qinna, Isi Al-Adham, Mai Khanfar

Molecules. 2023 Oct; 28(19): 6927. Published online 2023 Oct 4. doi: 10.3390/molecules28196927

PMCID:: PMC10574101

Abstract Article PDF–1.3M

Select item 104666847.

Metabolic engineering strategies for naringenin production enhancement in Streptomyces albidoflavus J1074

Suhui Ye, Patricia Magadán-Corpas, Álvaro Pérez-Valero, Claudio J. Villar, Felipe Lombó

Microb Cell Fact. 2023; 22: 167. Published online 2023 Aug 29. doi: 10.1186/s12934-023-02172-5

PMCID:: PMC10466684

Abstract Article PDF–2.0M

Select item 100062388.

Decrypting the programming of β-methylation in virginiamycin M biosynthesis

Sabrina Collin, Russell J. Cox, Cédric Paris, Christophe Jacob, Benjamin Chagot, Kira J. Weissman, Arnaud Gruez

Nat Commun. 2023; 14: 1327. Published online 2023 Mar 10. doi: 10.1038/s41467-023-36974-3

PMCID:: PMC10006238

Abstract Article PDF–2.7M

Select item 96692419.

Regiodivergent Palladium-Catalyzed Alkene Difunctionalization Reactions for the Construction of Methylene Cyclobutanes and Methylene Cyclopentanes

Evan C. Bornowski, James H. Shepich, Paige M. Carpenter, Derick R. White, Jessica E. Hatt, John P. Wolfe

Org Lett. Author manuscript; available in PMC 2023 Nov 11.

Published in final edited form as: Org Lett. 2022 Nov 11; 24(44): 8208–8212. Published online 2022 Oct 31. doi: 10.1021/acs.orglett.2c03308

PMCID:: PMC9669241

Abstract Article PDF–1.4M

Select item 877041410.

Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo

Hiran A. Prag, Laura Pala, Duvaraka Kula-Alwar, John F. Mulvey, Du Luping, Timothy E. Beach, Lee M. Booty, Andrew R. Hall, Angela Logan, Volha Sauchanka, Stuart T. Caldwell, Ellen L. Robb, Andrew M. James, Zhelong Xu, Kourosh Saeb-Parsy, Richard C. Hartley, Michael P. Murphy, Thomas Krieg

Cardiovasc Drugs Ther. 2022; 36(1): 1–13. Published online 2020 Jul 9. doi: 10.1007/s10557-020-07033-6

PMCID:: PMC8770414

Abstract Article PDF–895K

Select item 865800611.

Heterogenous Clinical Landscape in a Consanguineous Malonic Aciduria Family

Sarah Snanoudj, Stéphanie Torre, Bénédicte Sudrié-Arnaud, Lenaig Abily-Donval, Alice Goldenberg, Gajja S. Salomons, Stéphane Marret, Soumeya Bekri, Abdellah Tebani

Int J Mol Sci. 2021 Dec; 22(23): 12633. Published online 2021 Nov 23. doi: 10.3390/ijms222312633

PMCID:: PMC8658006

Abstract Article PDF–1.9M

Select item 846181512.

Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome

Jessica N. Peoples, Nasab Ghazal, Duc M. Duong, Katherine R. Hardin, Janet R. Manning, Nicholas T. Seyfried, Victor Faundez, Jennifer Q. Kwong

Am J Physiol Cell Physiol. 2021 Sep 1; 321(3): C519–C534. Published online 2021 Jul 28. doi: 10.1152/ajpcell.00156.2021

PMCID:: PMC8461815

Abstract Article

Select item 825238313.

Promoterless, Nuclease‐Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia

Randy J. Chandler, Leah E. Venturoni, Jing Liao, Brandon T. Hubbard, Jessica L. Schneller, Victoria Hoffmann, Susana Gordo, Shengwen Zang, Chih‐Wei Ko, Nelson Chau, Kyle Chiang, Mark A. Kay, Adi Barzel, Charles P. Venditti

Hepatology. 2021 Jun; 73(6): 2223–2237. Published online 2021 May 21. doi: 10.1002/hep.31570

Correction in:: Hepatology. 2022 Nov; 76(5): 1551.

PMCID:: PMC8252383

Abstract Article PDF–1.4M

Select item 803861514.

Natural Deep Eutectic Solvents for the Extraction of Bioactive Steroidal Saponins from Dioscoreae Nipponicae Rhizoma

Gui-Ya Yang, Jun-Na Song, Ya-Qing Chang, Lei Wang, Yu-Guang Zheng, Dan Zhang, Long Guo

Molecules. 2021 Apr; 26(7): 2079. Published online 2021 Apr 5. doi: 10.3390/molecules26072079

PMCID:: PMC8038615

Abstract Article PDF–3.1M

Select item 800260015.

The Influence of Metabolic Inhibitors, Antibiotics, and Microgravity on Intact Cell MALDI-TOF Mass Spectra of the Cyanobacterium Synechococcus Sp. UPOC S4

Marek Šebela, Martin Raus, Vladan Ondřej, Petr Hašler

Molecules. 2021 Mar; 26(6): 1683. Published online 2021 Mar 17. doi: 10.3390/molecules26061683

PMCID:: PMC8002600

Abstract Article PDF–20M

Select item 780374916.

Collective synthesis of acetylenic pharmaceuticals via enantioselective Nickel/Lewis acid-catalyzed propargylic alkylation

Xihao Chang, Jiayin Zhang, Lingzi Peng, Chang Guo

Nat Commun. 2021; 12: 299. Published online 2021 Jan 12. doi: 10.1038/s41467-020-20644-9

PMCID:: PMC7803749

Abstract Article PDF–1.4M

Select item 768370917.

Identification of the rhizospheric microbe and metabolites that led by the continuous cropping of ramie (Boehmeria nivea L. Gaud)

Yanzhou Wang, Siyuan Zhu, Touming Liu, Bing Guo, Fu Li, Xuehua Bai

Sci Rep. 2020; 10: 20408. Published online 2020 Nov 23. doi: 10.1038/s41598-020-77475-3

PMCID:: PMC7683709

Abstract Article PDF–5.6M

Select item 750730018.

A Korean child diagnosed with malonic aciduria harboring a novel start codon mutation following presentation with dilated cardiomyopathy

Seung Hoon Lee, Jung Min Ko, Mi‐Kyoung Song, Junghan Song, Kyung Sun Park

Mol Genet Genomic Med. 2020 Sep; 8(9): e1379. Published online 2020 Jun 30. doi: 10.1002/mgg3.1379

PMCID:: PMC7507300

Abstract Article PDF–379K

Select item 748239719.

Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker

Hiran A. Prag, Duvaraka Kula-Alwar, Laura Pala, Stuart T. Caldwell, Timothy E. Beach, Andrew M. James, Kourosh Saeb-Parsy, Thomas Krieg, Richard C. Hartley, Michael P. Murphy

Mol Pharm. 2020 Sep 8; 17(9): 3526–3540. Published online 2020 Jul 21. doi: 10.1021/acs.molpharmaceut.0c00533