PMC Links for Protein (Select 1084352541) - PMC

Select item 63833771.

Crohn’s disease IRGM risk alleles are associated with altered gene expression in human tissues

Teminioluwa A. Ajayi, Cynthia L. Innes, Sara A. Grimm, Prashant Rai, Ryan Finethy, Jörn Coers, Xuting Wang, Douglas A. Bell, John A. McGrath, Shepherd H. Schurman, Michael B. Fessler

Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1; 316(1): G95–G105. Published online 2018 Oct 18. doi: 10.1152/ajpgi.00196.2018

PMCID:: PMC6383377

Abstract Article

Select item 63720822.

The Crohn’s Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy

Subhash Mehto, Kautilya Kumar Jena, Parej Nath, Swati Chauhan, Srinivasa Prasad Kolapalli, Saroj Kumar Das, Pradyumna Kumar Sahoo, Ashish Jain, Gregory A. Taylor, Santosh Chauhan

Mol Cell. 2019 Feb 7; 73(3): 429–445.e7. doi: 10.1016/j.molcel.2018.11.018

PMCID:: PMC6372082

Abstract Article PDF–4.9M

Select item 60162173.

Polymorphisms in Autophagy-Related Gene IRGM Are Associated with Susceptibility to Autoimmune Thyroid Diseases

Qiu-ming Yao, Yuan-feng Zhu, Wen Wang, Zhen-yu Song, Xiao-qing Shao, Ling Li, Rong-hua Song, Xiao-fei An, Qiu Qin, Qian Li, Jin-an Zhang

Biomed Res Int. 2018; 2018: 7959707. Published online 2018 Jun 11. doi: 10.1155/2018/7959707

PMCID:: PMC6016217

Abstract Article PDF–701K

Select item 26285414.

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn disease susceptibility

Miles Parkes, Jeffrey C Barrett, Natalie Prescott, Mark Tremelling, Carl A Anderson, Sheila A Fisher, Roland G Roberts, Elaine R Nimmo, Fraser R Cummings, Dianne Soars, Hazel Drummond, Charlie W Lees, Saud A Khawaja, Richard Bagnall, Denis A Burke, Catherine E Todhunter, Tariq Ahmad, Clive M Onnie, Wendy McArdle, David Strachan, Graeme Bethel, Claire Bryan, Panos Deloukas, Alastair Forbes, Jeremy Sanderson, Derek P Jewell, Jack Satsangi, John C Mansfield, the Wellcome Trust Case Control Consortium, Lon Cardon, Christopher G Mathew

Nat Genet. Author manuscript; available in PMC 2009 Jan 19.

Published in final edited form as: Nat Genet. 2007 Jul; 39(7): 830–832. Published online 2007 Jun 6. doi: 10.1038/ng2061

PMCID:: PMC2628541

Abstract Article PDF–101K

Select item 12976485.

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

Cemalettin Bekpen, Julia P Hunn, Christoph Rohde, Iana Parvanova, Libby Guethlein, Diane M Dunn, Eva Glowalla, Maria Leptin, Jonathan C Howard

Genome Biol. 2005; 6(11): R92. Published online 2005 Oct 31. doi: 10.1186/gb-2005-6-11-r92

PMCID:: PMC1297648

Abstract Article PDF–1.7M

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