PMC Links for Protein (Select 12643334) - PMC

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Select item 64397201.

Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy

Lynne Rumping, Benjamin Büttner, Oliver Maier, Holger Rehmann, Maarten Lequin, Jan-Ulrich Schlump, Bernhard Schmitt, Birgit Schiebergen-Bronkhorst, Hubertus C. M. T. Prinsen, Michele Losa, Ralph Fingerhut, Johannes R. Lemke, Fried J. T. Zwartkruis, Roderick H. J. Houwen, Judith J. M. Jans, Nanda M. Verhoeven-Duif, Peter M. van Hasselt, Rami Jamra

JAMA Neurol. 2019 Mar; 76(3): 342–350. Published online 2018 Dec 21. doi: 10.1001/jamaneurol.2018.2941

PMCID:: PMC6439720

Abstract Article

Select item 63001662.

Design and Evaluation of Novel Glutaminase Inhibitors

Lee A. McDermott, Prema Iyer, Larry Vernetti, Shawn Rimer, Jingran Sun, Melissa Boby, Tianyi Yang, Michael Fioravanti, Jason O’Neil, Liwei Wang, Dylan Drakes, William Katt, Qingqiu Huang, Richard Cerione

Bioorg Med Chem. Author manuscript; available in PMC 2018 Dec 19.

Published in final edited form as: Bioorg Med Chem. 2016 Apr 15; 24(8): 1819–1839. Published online 2016 Mar 7. doi: 10.1016/j.bmc.2016.03.009

PMCID:: PMC6300166

Abstract Article PDF–2.1M

Select item 58461603.

Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism

Qingqiu Huang, Clint Stalnecker, Chengliang Zhang, Lee A. McDermott, Prema Iyer, Jason O'Neill, Shawn Reimer, Richard A. Cerione, William P. Katt

J Biol Chem. 2018 Mar 9; 293(10): 3535–3545. Published online 2018 Jan 9. doi: 10.1074/jbc.M117.810101

PMCID:: PMC5846160

Abstract Article PDF–3.3M

Select item 55008184.

The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats

Camila Cristina Pasquali, Zeyaul Islam, Douglas Adamoski, Igor Monteze Ferreira, Ricardo Diogo Righeto, Jefferson Bettini, Rodrigo Villares Portugal, Wyatt Wai-yin Yue, Ana Gonzalez, Sandra Martha Gomes Dias, Andre Luis Berteli Ambrosio

J Biol Chem. 2017 Jul 7; 292(27): 11572–11585. Published online 2017 May 19. doi: 10.1074/jbc.M117.787291

PMCID:: PMC5500818

Abstract Article PDF–3.6M

Select item 49296875.

Structural Basis for the Active Site Inhibition Mechanism of Human Kidney-Type Glutaminase (KGA)

K. Thangavelu, Qing Yun Chong, Boon Chuan Low, J. Sivaraman

Sci Rep. 2014; 4: 3827. Published online 2014 Jan 23. doi: 10.1038/srep03827

PMCID:: PMC4929687

Abstract Article PDF–1.8M

Select item 33566766.

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

K. Thangavelu, Catherine Qiurong Pan, Tobias Karlberg, Ganapathy Balaji, Mahesh Uttamchandani, Valiyaveettil Suresh, Herwig Schüler, Boon Chuan Low, J. Sivaraman

Proc Natl Acad Sci U S A. 2012 May 15; 109(20): 7705–7710. Published online 2012 Apr 26. doi: 10.1073/pnas.1116573109

PMCID:: PMC3356676

Abstract Article PDF–993K

Select item 32682727.

Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism

Alexandre Cassago, Amanda P. S. Ferreira, Igor M. Ferreira, Camila Fornezari, Emerson R. M. Gomes, Kai Su Greene, Humberto M. Pereira, Richard C. Garratt, Sandra M. G. Dias, Andre L. B. Ambrosio

Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4): 1092-1097. Published online 2012 Jan 6. doi: 10.1073/pnas.1112495109

PMCID:: PMC3268272

Abstract Article PDF–1.4M

Select item 30395708.

Initial characterization of the human central proteome

Thomas R Burkard, Melanie Planyavsky, Ines Kaupe, Florian P Breitwieser, Tilmann Bürckstümmer, Keiryn L Bennett, Giulio Superti-Furga, Jacques Colinge

BMC Syst Biol. 2011; 5: 17. Published online 2011 Jan 26. doi: 10.1186/1752-0509-5-17

PMCID:: PMC3039570

Abstract Article PDF–2.3M

Select item 5289289.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 693358010.

P-MAPA and IL-12 Differentially Regulate Proteins Associated with Ovarian Cancer Progression: A Proteomic Study

Luiz Antonio Lupi Júnior, Maira Smaniotto Cucielo, Raquel Fantin Domeniconi, Lucilene Delazari dos Santos, Henrique Spaulonci Silveira, Iseu da Silva Nunes, Marcelo Martinez, Francisco Eduardo Martinez, Wagner José Fávaro, Luiz Gustavo de Almeida Chuffa

ACS Omega. 2019 Dec 24; 4(26): 21761–21777. Published online 2019 Dec 11. doi: 10.1021/acsomega.9b02512

PMCID:: PMC6933580

Abstract Article PDF–6.2M

Select item 650506711.

Quantitative proteomic analyses of CD4⁺ and CD8⁺ T cells reveal differentially expressed proteins in multiple sclerosis patients and healthy controls

Tone Berge, Anna Eriksson, Ina Skaara Brorson, Einar August Høgestøl, Pål Berg-Hansen, Anne Døskeland, Olav Mjaavatten, Steffan Daniel Bos, Hanne F. Harbo, Frode Berven

Clin Proteomics. 2019; 16: 19. Published online 2019 May 8. doi: 10.1186/s12014-019-9241-5

PMCID:: PMC6505067

Abstract Article PDF–2.2M

Select item 643804012.

Hepatic protein Carbonylation profiles induced by lipid accumulation and oxidative stress for investigating cellular response to non-alcoholic fatty liver disease in vitro

Peerut Chienwichai, Onrapak Reamtong, Usa Boonyuen, Trairak Pisitkun, Poorichaya Somparn, Prapin Tharnpoophasiam, Suwalee Worakhunpiset, Supachai Topanurak

Proteome Sci. 2019; 17: 1. Published online 2019 Mar 27. doi: 10.1186/s12953-019-0149-9

PMCID:: PMC6438040

Abstract Article PDF–2.7M

Select item 639354813.

Differential epithelial and stromal protein profiles in cone and non-cone regions of keratoconus corneas

Gary Hin-Fai Yam, Matthias Fuest, Lei Zhou, Yu-Chi Liu, Lu Deng, Anita Sook-Yee Chan, Hon Shing Ong, Wei-Boon Khor, Marcus Ang, Jodhbir S. Mehta

Sci Rep. 2019; 9: 2965. Published online 2019 Feb 27. doi: 10.1038/s41598-019-39182-6

PMCID:: PMC6393548

Abstract Article PDF–2.5M

Select item 628485914.

Tissue proteomics outlines AGR2 AND LOX5 as markers for biochemical recurrence of prostate cancer

Giovanny Rodríguez-Blanco, Lona Zeneyedpour, Diederick Duijvesz, A. Marije Hoogland, Esther I. Verhoef, Charlotte F. Kweldam, Peter C. Burgers, Peter Sillevis Smitt, Chris H. Bangma, Guido Jenster, Geert J.L.H. van Leenders, Lennard J.M. Dekker, Theo M. Luider

Oncotarget. 2018 Nov 23; 9(92): 36444–36456. Published online 2018 Nov 23. doi: 10.18632/oncotarget.26342

PMCID:: PMC6284859

Abstract Article PDF–3.2M

Select item 627475115.

IL-18 and S100A12 Are Upregulated in Experimental Central Retinal Vein Occlusion

Lasse Jørgensen Cehofski, Anders Kruse, Svend Kirkeby, Alexander Nørgård Alsing, Jonas Ellegaard Nielsen, Kentaro Kojima, Bent Honoré, Henrik Vorum

Int J Mol Sci. 2018 Nov; 19(11): 3328. Published online 2018 Oct 25. doi: 10.3390/ijms19113328

PMCID:: PMC6274751

Abstract Article PDF–4.4M

Select item 609281916.

K_v1.3 channel blockade with the Vm24 scorpion toxin attenuates the CD4⁺ effector memory T cell response to TCR stimulation

José Ignacio Veytia-Bucheli, Juana María Jiménez-Vargas, Erika Isabel Melchy-Pérez, Monserrat Alba Sandoval-Hernández, Lourival Domingos Possani, Yvonne Rosenstein

Cell Commun Signal. 2018; 16: 45. Published online 2018 Aug 14. doi: 10.1186/s12964-018-0257-7