PMC Links for Protein (Select 166979751) - PMC

Select item 56564291.

Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP

Li Zhang, Prashant Rajbhandari, Christina Priest, Jaspreet Sandhu, Xiaohui Wu, Ryan Temel, Antonio Castrillo, Thomas Q de Aguiar Vallim, Tamer Sallam, Peter Tontonoz

eLife. 2017; 6: e28766. Published online 2017 Oct 25. doi: 10.7554/eLife.28766

PMCID:: PMC5656429

Abstract Article PDF–1.8M

Select item 30865782.

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-induced Insulin Resistant Mice

Yu Li, Shanqin Xu, Maria Mihaylova, Bin Zheng, Xiuyun Hou, Bingbing Jiang, Ogyi Park, Zhijun Luo, Etienne Lefai, John Y-J. Shyy, Bin Gao, Michel Wierzbicki, Tony J. Verbeuren, Reuben J. Shaw, Richard A. Cohen, Mengwei Zang

Cell Metab. Author manuscript; available in PMC 2012 Apr 6.

Published in final edited form as: Cell Metab. 2011 Apr 6; 13(4): 376–388. doi: 10.1016/j.cmet.2011.03.009

PMCID:: PMC3086578

Abstract Article PDF–3.1M

Select item 26803413.

Lineage-Specific Biology Revealed by a Finished Genome Assembly of the Mouse

Deanna M. Church, Leo Goodstadt, LaDeana W. Hillier, Michael C. Zody, Steve Goldstein, Xinwe She, Carol J. Bult, Richa Agarwala, Joshua L. Cherry, Michael DiCuccio, Wratko Hlavina, Yuri Kapustin, Peter Meric, Donna Maglott, Zoë Birtle, Ana C. Marques, Tina Graves, Shiguo Zhou, Brian Teague, Konstantinos Potamousis, Christopher Churas, Michael Place, Jill Herschleb, Ron Runnheim, Daniel Forrest, James Amos-Landgraf, David C. Schwartz, Ze Cheng, Kerstin Lindblad-Toh, Evan E. Eichler, Chris P. Ponting, The Mouse Genome Sequencing Consortium

PLoS Biol. 2009 May; 7(5): e1000112. Published online 2009 May 26. doi: 10.1371/journal.pbio.1000112

PMCID:: PMC2680341

Abstract Article PDF–1006K

Select item 5088224.

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

J D Horton, I Shimomura, M S Brown, R E Hammer, J L Goldstein, H Shimano

J Clin Invest. 1998 Jun 1; 101(11): 2331–2339. doi: 10.1172/JCI2961

PMCID:: PMC508822

Summary PDF–505K

Select item 1509685.

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, Joseph L. Goldstein, Michael S. Brown

J Clin Invest. 2002 May 1; 109(9): 1125–1131. doi: 10.1172/JCI15593

PMCID:: PMC150968

Article PDF–934K

Select item 47775256.

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway

Kevin A. Robertson, Wei Yuan Hsieh, Thorsten Forster, Mathieu Blanc, Hongjin Lu, Peter J. Crick, Eylan Yutuc, Steven Watterson, Kimberly Martin, Samantha J. Griffiths, Anton J. Enright, Mami Yamamoto, Madapura M. Pradeepa, Kimberly A. Lennox, Mark A. Behlke, Simon Talbot, Jürgen Haas, Lars Dölken, William J. Griffiths, Yuqin Wang, Ana Angulo, Peter Ghazal

PLoS Biol. 2016 Mar; 14(3): e1002364. Published online 2016 Mar 3. doi: 10.1371/journal.pbio.1002364

PMCID:: PMC4777525

Abstract Article PDF–7.0M

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