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Select item 58464541.

De novo variants in CAMK2A and CAMK2B cause neurodevelopmental disorders

Tenpei Akita, Kazushi Aoto, Mitsuhiro Kato, Masaaki Shiina, Hiroki Mutoh, Mitsuko Nakashima, Ichiro Kuki, Shin Okazaki, Shinichi Magara, Takashi Shiihara, Kenji Yokochi, Kaori Aiba, Jun Tohyama, Chihiro Ohba, Satoko Miyatake, Noriko Miyake, Kazuhiro Ogata, Atsuo Fukuda, Naomichi Matsumoto, Hirotomo Saitsu

Ann Clin Transl Neurol. 2018 Mar; 5(3): 280–296. Published online 2018 Jan 29. doi: 10.1002/acn3.528

PMCID:: PMC5846454

Article PDF–1.5M

Select item 32360322.

Analysis of CaM-kinase Signaling in Cells

Gary A. Wayman, Hiroshi Tokumitsu, Monika A. Davare, Thomas R. Soderling

Cell Calcium. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Cell Calcium. 2011 Jul; 50(1): 1–8. Published online 2011 Apr 29. doi: 10.1016/j.ceca.2011.02.007

PMCID:: PMC3236032

Article PDF–1.4M

Select item 28829613.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Article PDF–1.2M

Select item 27127194.

Patterns of somatic mutation in human cancer genomes

Christopher Greenman, Philip Stephens, Raffaella Smith, Gillian L. Dalgliesh, Christopher Hunter, Graham Bignell, Helen Davies, Jon Teague, Adam Butler, Claire Stevens, Sarah Edkins, Sarah O'Meara, Imre Vastrik, Esther E. Schmidt, Tim Avis, Syd Barthorpe, Gurpreet Bhamra, Gemma Buck, Bhudipa Choudhury, Jody Clements, Jennifer Cole, Ed Dicks, Simon Forbes, Kris Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jon Hinton, Andy Jenkinson, David Jones, Andy Menzies, Tatiana Mironenko, Janet Perry, Keiran Raine, Dave Richardson, Rebecca Shepherd, Alexandra Small, Calli Tofts, Jennifer Varian, Tony Webb, Sofie West, Sara Widaa, Andy Yates, Daniel P. Cahill, David N. Louis, Peter Goldstraw, Andrew G. Nicholson, Francis Brasseur, Leendert Looijenga, Barbara L. Weber, Yoke-Eng Chiew, Anna deFazio, Mel F. Greaves, Anthony R. Green, Peter Campbell, Ewan Birney, Douglas F. Easton, Georgia Chenevix-Trench, Min-Han Tan, Sok Kean Khoo, Bin Tean Teh, Siu Tsan Yuen, Suet Yi Leung, Richard Wooster, P. Andrew Futreal, Michael R. Stratton

Nature. Author manuscript; available in PMC 2009 Jul 20.

Published in final edited form as: Nature. 2007 Mar 8; 446(7132): 153–158. doi: 10.1038/nature05610

PMCID:: PMC2712719

Article PDF–867K

Select item 27091995.

Large-scale Proteomics Analysis of the Human Kinome

Felix S. Oppermann, Florian Gnad, Jesper V. Olsen, Renate Hornberger, Zoltán Greff, György Kéri, Matthias Mann, Henrik Daub

Mol Cell Proteomics. 2009 Jul; 8(7): 1751–1764. Published online 2009 Apr 15. doi: 10.1074/mcp.M800588-MCP200

PMCID:: PMC2709199

Article PDF–993K

Select item 26647436.

Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity

Gary A. Wayman, Yong-Seok Lee, Hiroshi Tokumitsu, Alcino Silva, Thomas R. Soderling

Neuron. Author manuscript; available in PMC 2009 Apr 2.

Published in final edited form as: Neuron. 2008 Sep 25; 59(6): 914–931. doi: 10.1016/j.neuron.2008.08.021

Correction in:: volume 64 on page 590

PMCID:: PMC2664743

Article PDF–1.5M

Select item 18177507.

Ca²⁺–calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise

Adam J Rose, Bente Kiens, Erik A Richter

J Physiol. 2006 Aug 1; 574(Pt 3): 889–903. Published online 2006 May 11. doi: 10.1113/jphysiol.2006.111757

PMCID:: PMC1817750

Article PDF–702K

Select item 5289288.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Article PDF–140K

Select item 70166879.

CD38, CD157, and RAGE as Molecular Determinants for Social Behavior

Haruhiro Higashida, Minako Hashii, Yukie Tanaka, Shigeru Matsukawa, Yoshihiro Higuchi, Ryosuke Gabata, Makoto Tsubomoto, Noriko Seishima, Mitsuyo Teramachi, Taiki Kamijima, Tsuyoshi Hattori, Osamu Hori, Chiharu Tsuji, Stanislav M. Cherepanov, Anna A. Shabalova, Maria Gerasimenko, Kana Minami, Shigeru Yokoyama, Sei-ichi Munesue, Ai Harashima, Yasuhiko Yamamoto, Alla B. Salmina, Olga Lopatina

Cells. 2020 Jan; 9(1): 62. Published online 2019 Dec 25. doi: 10.3390/cells9010062

PMCID:: PMC7016687

Article PDF–2.2M

Select item 681496610.

ATXN1 N-terminal region explains the binding differences of wild-type and expanded forms

Sara Rocha, Jorge Vieira, Noé Vázquez, Hugo López-Fernández, Florentino Fdez-Riverola, Miguel Reboiro-Jato, André D. Sousa, Cristina P. Vieira

BMC Med Genomics. 2019; 12: 145. Published online 2019 Oct 26. doi: 10.1186/s12920-019-0594-4

PMCID:: PMC6814966

Article PDF–2.1M

Select item 650506711.

Quantitative proteomic analyses of CD4⁺ and CD8⁺ T cells reveal differentially expressed proteins in multiple sclerosis patients and healthy controls

Tone Berge, Anna Eriksson, Ina Skaara Brorson, Einar August Høgestøl, Pål Berg-Hansen, Anne Døskeland, Olav Mjaavatten, Steffan Daniel Bos, Hanne F. Harbo, Frode Berven

Clin Proteomics. 2019; 16: 19. Published online 2019 May 8. doi: 10.1186/s12014-019-9241-5

PMCID:: PMC6505067

Article PDF–2.2M

Select item 608776412.

System Pharmacology-Based Strategy to Decode the Synergistic Mechanism of Zhi-zhu Wan for Functional Dyspepsia

Chun Wang, Qing Ren, Xue-Tong Chen, Zhi-Qian Song, Zhang-Chi Ning, Jia-He Gan, Xin-Ling Ma, Dong-Rui Liang, Dao-Gang Guan, Zhen-Li Liu, Ai-Ping Lu

Front Pharmacol. 2018; 9: 841. Published online 2018 Aug 6. doi: 10.3389/fphar.2018.00841

PMCID:: PMC6087764

Article PDF–4.7M

Select item 606532613.

A network pharmacology-based approach to analyse potential targets of traditional herbal formulas: An example of Yu Ping Feng decoction

Huali Zuo, Qianru Zhang, Shibing Su, Qilong Chen, Fengqing Yang, Yuanjia Hu

Sci Rep. 2018; 8: 11418. Published online 2018 Jul 30. doi: 10.1038/s41598-018-29764-1

PMCID:: PMC6065326

Article PDF–3.6M

Select item 584679414.

Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy

Silvia Parolo, Luca Marchetti, Mario Lauria, Karla Misselbeck, Marie-Pier Scott-Boyer, Laura Caberlotto, Corrado Priami

PLoS One. 2018; 13(3): e0194225. Published online 2018 Mar 12. doi: 10.1371/journal.pone.0194225

PMCID:: PMC5846794

Article PDF–7.2M

Select item 584411415.

Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila, Andrea Bileck, Besnik Muqaku, Lukas Janker, Ossia M. Eichhoff, Phil F. Cheng, Reinhard Dummer, Mitchell P. Levesque, Christopher Gerner, Verena Paulitschke

Clin Proteomics. 2018; 15: 13. Published online 2018 Mar 9. doi: 10.1186/s12014-018-9189-x

PMCID:: PMC5844114

Article PDF–2.9M

Select item 581348916.

The Maternal Plasma Proteome Changes as a Function of Gestational Age in Normal Pregnancy: a Longitudinal Study

Roberto Romero, Offer Erez, Eli Maymon, Piya Chaemsaithong, Zhonghui Xu, Percy Pacora, Tinnakorn Chaiworapongsa, Bogdan Done, Sonia S. Hassan, Adi L. Tarca

Am J Obstet Gynecol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Am J Obstet Gynecol. 2017 Jul; 217(1): 67.e1–67.e21. Published online 2017 Mar 3. doi: 10.1016/j.ajog.2017.02.037

PMCID:: PMC5813489

Article PDF–872K

Select item 567367117.

De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability

Sébastien Küry, Geeske M. van Woerden, Thomas Besnard, Martina Proietti Onori, Xénia Latypova, Meghan C. Towne, Megan T. Cho, Trine E. Prescott, Melissa A. Ploeg, Stephan Sanders, Holly A.F. Stessman, Aurora Pujol, Ben Distel, Laurie A. Robak, Jonathan A. Bernstein, Anne-Sophie Denommé-Pichon, Gaëtan Lesca, Elizabeth A. Sellars, Jonathan Berg, Wilfrid Carré, Øyvind Løvold Busk, Bregje W.M. van Bon, Jeff L. Waugh, Matthew Deardorff, George E. Hoganson, Katherine B. Bosanko, Diana S. Johnson, Tabib Dabir, Øystein Lunde Holla, Ajoy Sarkar, Kristian Tveten, Julitta de Bellescize, Geir J. Braathen, Paulien A. Terhal, Dorothy K. Grange, Arie van Haeringen, Christina Lam, Ghayda Mirzaa, Jennifer Burton, Elizabeth J. Bhoj, Jessica Douglas, Avni B. Santani, Addie I. Nesbitt, Katherine L. Helbig, Marisa V. Andrews, Amber Begtrup, Sha Tang, Koen L.I. van Gassen, Jane Juusola, Kimberly Foss, Gregory M. Enns, Ute Moog, Katrin Hinderhofer, Nagarajan Paramasivam, Sharyn Lincoln, Brandon H. Kusako, Pierre Lindenbaum, Eric Charpentier, Catherine B. Nowak, Elouan Cherot, Thomas Simonet, Claudia A.L. Ruivenkamp, Sihoun Hahn, Catherine A. Brownstein, Fan Xia, Sébastien Schmitt, Wallid Deb, Dominique Bonneau, Mathilde Nizon, Delphine Quinquis, Jamel Chelly, Gabrielle Rudolf, Damien Sanlaville, Philippe Parent, Brigitte Gilbert-Dussardier, Annick Toutain, Vernon R. Sutton, Jenny Thies, Lisenka E.L.M. Peart-Vissers, Pierre Boisseau, Marie Vincent, Andreas M. Grabrucker, Christèle Dubourg, Undiagnosed Diseases Network, Wen-Hann Tan, Nienke E. Verbeek, Martin Granzow, Gijs W.E. Santen, Jay Shendure, Bertrand Isidor, Laurent Pasquier, Richard Redon, Yaping Yang, Matthew W. State, Tjitske Kleefstra, Benjamin Cogné, GEM HUGO, Deciphering Developmental Disorders Study, Slavé Petrovski, Kyle Retterer, Evan E. Eichler, Jill A. Rosenfeld, Pankaj B. Agrawal, Stéphane Bézieau, Sylvie Odent, Ype Elgersma, Sandra Mercier

Am J Hum Genet. 2017 Nov 2; 101(5): 768–788. Published online 2017 Nov 2. doi: 10.1016/j.ajhg.2017.10.003

PMCID:: PMC5673671

Article PDF–3.3M

Select item 533310218.

Identification of serum protein biomarkers for utrophin based DMD therapy

Simon Guiraud, Benjamin Edwards, Sarah E. Squire, Arran Babbs, Nandini Shah, Adam Berg, Huijia Chen, Kay E. Davies

Sci Rep. 2017; 7: 43697. Published online 2017 Mar 2. doi: 10.1038/srep43697

PMCID:: PMC5333102

Article PDF–1.2M

Select item 510112419.

Mass spectrometric phosphoproteome analysis of HIV-infected brain reveals novel phosphorylation sites and differential phosphorylation patterns

Lerna Uzasci, Sungyoung Auh, Robert J. Cotter, Avindra Nath

Proteomics Clin Appl. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Proteomics Clin Appl. 2016 Feb; 10(2): 126–135. Published online 2015 Aug 12. doi: 10.1002/prca.201400134

PMCID:: PMC5101124

Article PDF–737K

Select item 471954220.

Combining patient proteomics and in vitro cardiomyocyte phenotype testing to identify potential mediators of heart failure with preserved ejection fraction

Roseanne Raphael, Diana Purushotham, Courtney Gastonguay, Marla A. Chesnik, Wai-Meng Kwok, Hsiang-En Wu, Sanjiv J. Shah, Shama P. Mirza, Jennifer L. Strande

J Transl Med. 2016; 14: 18. Published online 2016 Jan 20. doi: 10.1186/s12967-016-0774-3

PMCID:: PMC4719542

Article PDF–1.2M

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