PMC Links for Protein (Select 49574546) - PMC

Select item 67786451.

Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome

Yasuo Kubota, Kumiko Uryu, Tatsuya Ito, Masafumi Seki, Tomoko Kawai, Tomoya Isobe, Tadayuki Kumagai, Tsutomu Toki, Kenichi Yoshida, Hiromichi Suzuki, Keisuke Kataoka, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Kentaro Ohki, Nobutaka Kiyokawa, Jiro Kagawa, Satoru Miyano, Akira Oka, Yasuhide Hayashi, Seishi Ogawa, Kiminori Terui, Atsushi Sato, Kenichiro Hata, Etsuro Ito, Junko Takita

Cancer Sci. 2019 Oct; 110(10): 3358–3367. Published online 2019 Sep 10. doi: 10.1111/cas.14160

PMCID:: PMC6778645

Abstract Article PDF–2.1M

Select item 66702202.

RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer

Qingyuan Li, Qiuhua Lai, Chengcheng He, Yuxin Fang, Qun Yan, Yue Zhang, Xinke Wang, Chuncai Gu, Yiqing Wang, Liangying Ye, Lu Han, Xin Lin, Junsheng Chen, Jianqun Cai, Aimin Li, Side Liu

J Exp Clin Cancer Res. 2019; 38: 334. Published online 2019 Aug 1. doi: 10.1186/s13046-019-1330-9

PMCID:: PMC6670220

Abstract Article PDF–4.4M

Select item 65028103.

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription

Navdeep Malik, Hualong Yan, Nellie Moshkovich, Murali Palangat, Howard Yang, Vanesa Sanchez, Zhuo Cai, Tyler J. Peat, Shunlin Jiang, Chengyu Liu, Maxwell Lee, Beverly A. Mock, Stuart H. Yuspa, Daniel Larson, Lalage M. Wakefield, Jing Huang

Nat Commun. 2019; 10: 2071. Published online 2019 May 6. doi: 10.1038/s41467-019-10102-6

PMCID:: PMC6502810

Abstract Article PDF–3.1M

Select item 529424.

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

H Miyoshi, K Shimizu, T Kozu, N Maseki, Y Kaneko, M Ohki

Proc Natl Acad Sci U S A. 1991 Dec 1; 88(23): 10431–10434. doi: 10.1073/pnas.88.23.10431

PMCID:: PMC52942

Summary Page Browse PDF–965K

Select item 58802545.

Identification of novel MECOM gene fusion and personalized therapeutic targets through integrative clinical sequencing in secondary acute myeloid leukemia in a patient with severe congenital neutropenia: a case report and literature review

James A. Connelly, Rajen J. Mody, Yi-Mi Wu, Dan R. Robinson, Robert J. Lonigro, Pankaj Vats, Erica Rabban, Bailey Anderson, Kelly Walkovich

Cold Spring Harb Mol Case Stud. 2018 Apr; 4(2): a002204. doi: 10.1101/mcs.a002204

PMCID:: PMC5880254

Abstract Article PDF–2.6M

Select item 55350276.

The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1–RUNX1T1

Taishi Yonezawa, Hirotaka Takahashi, Shiori Shikata, Xiaoxiao Liu, Moe Tamura, Shuhei Asada, Tsuyoshi Fukushima, Tomofusa Fukuyama, Yosuke Tanaka, Tatsuya Sawasaki, Toshio Kitamura, Susumu Goyama

J Biol Chem. 2017 Jul 28; 292(30): 12528–12541. Published online 2017 May 23. doi: 10.1074/jbc.M117.785675

PMCID:: PMC5535027

Abstract Article PDF–2.9M

Select item 50466467.

Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defects

Ben Johnson, Gillian C. Lowe, Jane Futterer, Marie Lordkipanidzé, David MacDonald, Michael A. Simpson, Isabel Sanchez-Guiú, Sian Drake, Danai Bem, Vincenzo Leo, Sarah J. Fletcher, Ban Dawood, José Rivera, David Allsup, Tina Biss, Paula HB Bolton-Maggs, Peter Collins, Nicola Curry, Charlotte Grimley, Beki James, Mike Makris, Jayashree Motwani, Sue Pavord, Katherine Talks, Jecko Thachil, Jonathan Wilde, Mike Williams, Paul Harrison, Paul Gissen, Stuart Mundell, Andrew Mumford, Martina E. Daly, Steve P. Watson, Neil V. Morgan

Haematologica. 2016 Oct; 101(10): 1170–1179. doi: 10.3324/haematol.2016.146316

PMCID:: PMC5046646

Abstract Article PDF–820K

Select item 40071978.

RUNX family members are covalently modified and regulated by PIAS1-mediated sumoylation

J-H Kim, J-W Jang, Y-S Lee, J-W Lee, X-Z Chi, Y-H Li, M-K Kim, D-M Kim, B-S Choi, J Kim, H-M Kim, A van Wijnen, IlY Park, S-C Bae

Oncogenesis. 2014 Apr; 3(4): e101. Published online 2014 Apr 28. doi: 10.1038/oncsis.2014.15

PMCID:: PMC4007197

Abstract Article PDF–1.0M

Select item 37349019.

Recognizing familial myeloid leukemia in adults

Eric M. Nickels, Jesse Soodalter, Jane E. Churpek, Lucy A. Godley

Ther Adv Hematol. 2013 Aug; 4(4): 254–269. doi: 10.1177/2040620713487399

PMCID:: PMC3734901

Abstract Article PDF–749K

Select item 325723610.

SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b

Bhavna Varshney, Sudhakar Agnihotram, Yee-Joo Tan, Ralph Baric, Sunil K. Lal

PLoS One. 2012; 7(1): e29542. Published online 2012 Jan 12. doi: 10.1371/journal.pone.0029542

Correction in:: PLoS One. 2012; 7(3): 10.1371/annotation/64ae6047-0f9b-4d17-a065-e08c153aa435.

PMCID:: PMC3257236

Abstract Article PDF–461K

Select item 289603311.

Expression analysis of Runx3 and other Runx family members during Xenopus development

Byung-Yong Park, Jean-Pierre Saint-Jeannet

Gene Expr Patterns. Author manuscript; available in PMC 2010 Jul 2.

Published in final edited form as: Gene Expr Patterns. 2010 Jun; 10(4-5): 159–166. Published online 2010 Apr 28. doi: 10.1016/j.gep.2010.04.004

PMCID:: PMC2896033

Abstract Article PDF–4.6M

Select item 257280212.

PEBP2-β/CBF-β–dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis

Hee-Jun Wee, Dominic Chih-Cheng Voon, Suk-Chul Bae, Yoshiaki Ito

Blood. 2008 Nov 1; 112(9): 3777–3787. Prepublished online 2008 Aug 11. doi: 10.1182/blood-2008-01-134122

PMCID:: PMC2572802

Abstract Article

Select item 226553113.

Evolution of a Core Gene Network for Skeletogenesis in Chordates

Jochen Hecht, Sigmar Stricker, Ulrike Wiecha, Asita Stiege, Georgia Panopoulou, Lars Podsiadlowski, Albert J. Poustka, Christoph Dieterich, Siegfried Ehrich, Julia Suvorova, Stefan Mundlos, Volkhard Seitz

PLoS Genet. 2008 Mar; 4(3): e1000025. Published online 2008 Mar 21. doi: 10.1371/journal.pgen.1000025

PMCID:: PMC2265531

Abstract Article PDF–781K

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