PMC Links for Protein (Select 729008) - PMC

Select item 69859361.

2-Amino-2,3-dihydro-1H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy

Dongsheng Zhu, Huocong Huang, Daniel M. Pinkas, Jinfeng Luo, Debolina Ganguly, Alice E. Fox, Emily Arner, Qiuping Xiang, Zheng-Chao Tu, Alex N. Bullock, Rolf A. Brekken, Ke Ding, Xiaoyun Lu

J Med Chem. 2019 Aug 22; 62(16): 7431–7444. Published online 2019 Jul 16. doi: 10.1021/acs.jmedchem.9b00365

PMCID:: PMC6985936

Abstract Article PDF–4.2M

Select item 62878922.

Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-isopropyl-N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2

Zhen Wang, Yali Zhang, Daniel M. Pinkas, Alice E. Fox, Jinfeng Luo, Huocong Huang, Shengyang Cui, Qiuping Xiang, Tingting Xu, Qiuju Xun, Dongsheng Zhu, Zhengchao Tu, Xiaomei Ren, Rolf A. Brekken, Alex N. Bullock, Guang Liang, Ke Ding, Xiaoyun Lu

J Med Chem. 2018 Sep 13; 61(17): 7977–7990. Published online 2018 Aug 3. doi: 10.1021/acs.jmedchem.8b01045

PMCID:: PMC6287892

Abstract Article PDF–6.7M

Select item 62506013.

Phosphocode-dependent functional dichotomy of a common co-receptor in plant signaling

Artemis Perraki, Thomas A. DeFalco, Paul Derbyshire, Julian Avila, David Séré, Jan Sklenar, Xingyun Qi, Lena Stransfeld, Benjamin Schwessinger, Yasuhiro Kadota, Alberto P. Macho, Shushu Jiang, Daniel Couto, Keiko U. Torii, Frank L.H. Menke, Cyril Zipfel

Nature. Author manuscript; available in PMC 2019 Mar 3.

Published in final edited form as: Nature. 2018 Sep; 561(7722): 248–252. Published online 2018 Sep 3. doi: 10.1038/s41586-018-0471-x

Correction in:: Nature. 2018 Nov; 563(7733): E30.

PMCID:: PMC6250601

Abstract Article PDF–8.9M

Select item 58609614.

Application of large scale aptamer-based proteomic profiling to “planned” myocardial infarctions

Jaison Jacob, Debby Ngo, Nancy Finkel, Rebecca Pitts, Scott Gleim, Mark D. Benson, Michelle J. Keyes, Laurie A. Farrell, Thomas Morgan, Lori L. Jennings, Robert E. Gerszten

Circulation. Author manuscript; available in PMC 2019 Mar 20.

Published in final edited form as: Circulation. 2018 Mar 20; 137(12): 1270–1277. Published online 2017 Dec 8. doi: 10.1161/CIRCULATIONAHA.117.029443

PMCID:: PMC5860961

Abstract Article PDF–204K

Select item 58134895.

The Maternal Plasma Proteome Changes as a Function of Gestational Age in Normal Pregnancy: a Longitudinal Study

Roberto Romero, Offer Erez, Eli Maymon, Piya Chaemsaithong, Zhonghui Xu, Percy Pacora, Tinnakorn Chaiworapongsa, Bogdan Done, Sonia S. Hassan, Adi L. Tarca

Am J Obstet Gynecol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Am J Obstet Gynecol. 2017 Jul; 217(1): 67.e1–67.e21. Published online 2017 Mar 3. doi: 10.1016/j.ajog.2017.02.037

PMCID:: PMC5813489

Abstract Article PDF–872K

Select item 56506616.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors

Stephen PH Alexander, Doriano Fabbro, Eamonn Kelly, Neil V Marrion, John A Peters, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators

Br J Pharmacol. 2017 Dec; 174(Suppl Suppl 1): S225–S271. Published online 2017 Oct 21. doi: 10.1111/bph.13876

PMCID:: PMC5650661

Abstract Article PDF–1.1M

Select item 55447727.

Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis

Nicholas Johnson, Jana Březinová, Elaine Stephens, Emma Burbridge, Matthew Freeman, Colin Adrain, Kvido Strisovsky

Sci Rep. 2017; 7: 7283. Published online 2017 Aug 4. doi: 10.1038/s41598-017-07556-3

PMCID:: PMC5544772

Abstract Article PDF–4.0M

Select item 55283568.

Effect of antiangiogenic therapy on tumor growth, vasculature and kinase activity in basal‐ and luminal‐like breast cancer xenografts

Evita M. Lindholm, Alexandr Kristian, Hawa Nalwoga, Kristi Krüger, Ståle Nygård, Lars A. Akslen, Gunhild M. Mælandsmo, Olav Engebraaten

Mol Oncol. 2012 Aug; 6(4): 418–427. Published online 2012 Mar 31. doi: 10.1016/j.molonc.2012.03.006

Correction in:: Mol Oncol. 2013 Oct; 7(5): 1000.

PMCID:: PMC5528356

Abstract Article PDF–590K

Select item 50553579.

Large-Scale Off-Target Identification Using Fast and Accurate Dual Regularized One-Class Collaborative Filtering and Its Application to Drug Repurposing

Hansaim Lim, Aleksandar Poleksic, Yuan Yao, Hanghang Tong, Di He, Luke Zhuang, Patrick Meng, Lei Xie

PLoS Comput Biol. 2016 Oct; 12(10): e1005135. Published online 2016 Oct 7. doi: 10.1371/journal.pcbi.1005135

Correction in:: PLoS Comput Biol. 2017 Jan; 13(1): e1005312.

PMCID:: PMC5055357

Abstract Article PDF–6.0M

Select item 471820810.

The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors

Stephen PH Alexander, Doriano Fabbro, Eamonn Kelly, Neil Marrion, John A Peters, Helen E Benson, Elena Faccenda, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators

Br J Pharmacol. 2015 Dec; 172(24): 5979–6023. Published online 2015 Dec 9. doi: 10.1111/bph.13353

PMCID:: PMC4718208

Abstract Article PDF–1.2M

Select item 405874711.

Structural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase Inhibitors

Peter Canning, Li Tan, Kiki Chu, Sam W. Lee, Nathanael S. Gray, Alex N. Bullock

J Mol Biol. 2014 Jun 26; 426(13): 2457–2470. doi: 10.1016/j.jmb.2014.04.014

PMCID:: PMC4058747

Abstract Article PDF–3.0M

Select item 404746912.

Quantitative Chemical Proteomics Identifies Novel Targets of the Anti-cancer Multi-kinase Inhibitor E-3810

Mara Colzani, Roberta Noberini, Mauro Romanenghi, Gennaro Colella, Maurizio Pasi, Daniele Fancelli, Mario Varasi, Saverio Minucci, Tiziana Bonaldi

Mol Cell Proteomics. 2014 Jun; 13(6): 1495–1509. Published online 2014 Apr 2. doi: 10.1074/mcp.M113.034173

PMCID:: PMC4047469

Abstract Article PDF–1.2M

Select item 403636213.

Normal Activation of Discoidin Domain Receptor 1 Mutants with Disulfide Cross-links, Insertions, or Deletions in the Extracellular Juxtamembrane Region: MECHANISTIC IMPLICATIONS

Huifang Xu, Takemoto Abe, Justin K. H. Liu, Irina Zalivina, Erhard Hohenester, Birgit Leitinger

J Biol Chem. 2014 May 9; 289(19): 13565–13574. Published online 2014 Mar 26. doi: 10.1074/jbc.M113.536144

PMCID:: PMC4036362

Abstract Article PDF–3.0M

Select item 389229114.

The Concise Guide to Pharmacology 2013/14: Catalytic Receptors

Stephen PH Alexander, Helen E Benson, Elena Faccenda, Adam J Pawson, Joanna L Sharman, Michael Spedding, John A Peters, Anthony J Harmar

Br J Pharmacol. 2013 Dec; 170(8): 1676–1705. Published online 2013 Dec 17. doi: 10.1111/bph.12449

PMCID:: PMC3892291

Abstract Article PDF–939K

Select item 332071215.

Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling

Federico Carafoli, Marie Cathrin Mayer, Kazushige Shiraishi, Mira Anguelova Pecheva, Lai Yi Chan, Ruodan Nan, Birgit Leitinger, Erhard Hohenester

Structure. 2012 Apr 4; 20-178(4): 688–697. doi: 10.1016/j.str.2012.02.011

PMCID:: PMC3320712

Abstract Article PDF–1.2M

Select item 326812116.

Leucine-Rich repeat receptor kinases are sporadically distributed in eukaryotic genomes

Anne Diévart, Nicolas Gilbert, Gaétan Droc, Agnès Attard, Matthieu Gourgues, Emmanuel Guiderdoni, Christophe Périn

BMC Evol Biol. 2011; 11: 367. Published online 2011 Dec 20. doi: 10.1186/1471-2148-11-367

PMCID:: PMC3268121

Abstract Article PDF–469K

Select item 313690517.

Differential occurrence of protein intrinsic disorder in the cytoplasmic signaling domains of cell receptors

Alexander B Sigalov, Vladimir N Uversky

Self Nonself. 2011 Jan-Mar; 2(1): 55–72. Published online 2011 Jan 1. doi: 10.4161/self.2.1.14790

PMCID:: PMC3136905

Abstract Article PDF–11M

Select item 5854918.

Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinases

Shin-Han Shiu, Anthony B. Bleecker

Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19): 10763–10768. Published online 2001 Aug 28. doi: 10.1073/pnas.181141598

PMCID:: PMC58549

Abstract Article PDF–722K

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