PMC Links for Protein (Select 730230) - PMC

Select item 35167481.

Serine 363 Is Required for Nociceptin/Orphanin FQ Opioid Receptor (NOPR) Desensitization, Internalization, and Arrestin Signaling

Nancy R. Zhang, William Planer, Edward R. Siuda, Hu-Chen Zhao, Lucy Stickler, Steven D. Chang, Madison A. Baird, Yu-Qing Cao, Michael R. Bruchas

J Biol Chem. 2012 Dec 7; 287(50): 42019–42030. Published online 2012 Oct 19. doi: 10.1074/jbc.M112.405696

PMCID:: PMC3516748

Article PDF–2.5M

Select item 33569282.

Structure of the Nociceptin/Orphanin FQ Receptor in Complex with a Peptide Mimetic

Aaron A. Thompson, Wei Liu, Eugene Chun, Vsevolod Katritch, Huixian Wu, Eyal Vardy, Xi-Ping Huang, Claudio Trapella, Remo Guerrini, Girolamo Calo, Bryan L. Roth, Vadim Cherezov, Raymond C. Stevens

Nature. Author manuscript; available in PMC 2012 Nov 16.

Published in final edited form as: Nature. 2012 May 17; 485(7398): 395–399. Published online 2012 May 16. doi: 10.1038/nature11085

PMCID:: PMC3356928

Article PDF–1.1M

Select item 5289283.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Article PDF–140K

Select item 60877644.

System Pharmacology-Based Strategy to Decode the Synergistic Mechanism of Zhi-zhu Wan for Functional Dyspepsia

Chun Wang, Qing Ren, Xue-Tong Chen, Zhi-Qian Song, Zhang-Chi Ning, Jia-He Gan, Xin-Ling Ma, Dong-Rui Liang, Dao-Gang Guan, Zhen-Li Liu, Ai-Ping Lu

Front Pharmacol. 2018; 9: 841. Published online 2018 Aug 6. doi: 10.3389/fphar.2018.00841

PMCID:: PMC6087764

Article PDF–4.7M

Select item 60453675.

Support Vector Machine Classification and Regression Prioritize Different Structural Features for Binary Compound Activity and Potency Value Prediction

Raquel Rodríguez-Pérez, Martin Vogt, Jürgen Bajorath

ACS Omega. 2017 Oct 31; 2(10): 6371–6379. Published online 2017 Oct 4. doi: 10.1021/acsomega.7b01079

PMCID:: PMC6045367

Article PDF–1.3M

Select item 56506676.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein‐coupled receptors

Stephen PH Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Neil V Marrion, John A Peters, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators

Br J Pharmacol. 2017 Dec; 174(Suppl Suppl 1): S17–S129. Published online 2017 Oct 21. doi: 10.1111/bph.13878

PMCID:: PMC5650667

Article PDF–3.7M

Select item 54175947.

Influence of Varying Training Set Composition and Size on Support Vector Machine-Based Prediction of Active Compounds

Raquel Rodríguez-Pérez, Martin Vogt, Jürgen Bajorath

J Chem Inf Model. 2017 Apr 24; 57(4): 710–716. Published online 2017 Apr 4. doi: 10.1021/acs.jcim.7b00088

PMCID:: PMC5417594

Article PDF–1.5M

Select item 51612618.

Estimation of Maximum Recommended Therapeutic Dose Using Predicted Promiscuity and Potency

T Liu, T Oprea, O Ursu, C Hasselgren, RB Altman

Clin Transl Sci. 2016 Dec; 9(6): 311–320. Published online 2016 Oct 13. doi: 10.1111/cts.12422

PMCID:: PMC5161261

Article PDF–319K

Select item 47182109.

The Concise Guide to PHARMACOLOGY 2015/16: G protein‐coupled receptors

Stephen PH Alexander, Anthony P Davenport, Eamonn Kelly, Neil Marrion, John A Peters, Helen E Benson, Elena Faccenda, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators

Br J Pharmacol. 2015 Dec; 172(24): 5744–5869. Published online 2015 Dec 9. doi: 10.1111/bph.13348

PMCID:: PMC4718210

Article PDF–4.3M

Select item 461945410.

Target prediction utilising negative bioactivity data covering large chemical space

Lewis H. Mervin, Avid M. Afzal, Georgios Drakakis, Richard Lewis, Ola Engkvist, Andreas Bender

J Cheminform. 2015; 7: 51. Published online 2015 Oct 24. doi: 10.1186/s13321-015-0098-y

PMCID:: PMC4619454

Article PDF–2.0M

Select item 403451511.

Topography Prediction of Helical Transmembrane Proteins by a New Modification of the Sliding Window Method

Maria N. Simakova, Nikolai N. Simakov

Biomed Res Int. 2014; 2014: 921218. Published online 2014 May 11. doi: 10.1155/2014/921218

Correction in:: Biomed Res Int. 2017; 2017: 7180293.

PMCID:: PMC4034515

Article PDF–650K

Select item 391524112.

Chemogenomics knowledgebased polypharmacology analyses of drug abuse related G-protein coupled receptors and their ligands

Xiang-Qun Xie, Lirong Wang, Haibin Liu, Qin Ouyang, Cheng Fang, Weiwei Su

Front Pharmacol. 2014; 5: 3. Prepublished online 2013 Dec 4. Published online 2014 Feb 6. doi: 10.3389/fphar.2014.00003

PMCID:: PMC3915241

Article PDF–1.1M

Select item 389228713.

The Concise Guide to Pharmacology 2013/14: G Protein-Coupled Receptors

Stephen PH Alexander, Helen E Benson, Elena Faccenda, Adam J Pawson, Joanna L Sharman, Michael Spedding, John A Peters, Anthony J Harmar

Br J Pharmacol. 2013 Dec; 170(8): 1459–1581. Published online 2013 Dec 17. doi: 10.1111/bph.12445

PMCID:: PMC3892287

Article PDF–2.9M

Select item 341882314.

Synthesis and Properties of Dodecyl Trehaloside Detergents for Membrane Protein Studies

Houchao Tao, Yu Fu, Aaron Thompson, Sung Chang Lee, Nicholas Mahoney, Raymond C. Stevens, Qinghai Zhang

Langmuir. Author manuscript; available in PMC 2013 Jul 31.

Published in final edited form as: Langmuir. 2012 Jul 31; 28(30): 11173–11181. Published online 2012 Jul 20. doi: 10.1021/la3020404

PMCID:: PMC3418823

Article PDF–3.0M

Select item 326475515.

GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles

Aaron A. Thompson, Jeffrey J. Liu, Eugene Chun, Daniel Wacker, Huixian Wu, Vadim Cherezov, Raymond C. Stevens

Methods. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Methods. 2011 Dec; 55(4): 310–317. Published online 2011 Oct 21. doi: 10.1016/j.ymeth.2011.10.011

PMCID:: PMC3264755

Article PDF–2.4M

Select item 317197116.

Molecular Architecture of G Protein-Coupled Receptors

A. Michiel van Rhee, Kenneth A. Jacobson

Drug Dev Res. Author manuscript; available in PMC 2011 Sep 13.

Published in final edited form as: Drug Dev Res. 1996 Jan 1; 37(1): 1–38. doi: 10.1002/(SICI)1098-2299(199601)37:1<1::AID-DDR1>3.0.CO;2-S

PMCID:: PMC3171971

Article PDF–1.0M

Select item 294592117.

The systematic annotation of the three main GPCR families in Reactome

Bijay Jassal, Steven Jupe, Michael Caudy, Ewan Birney, Lincoln Stein, Henning Hermjakob, Peter D’Eustachio

Database (Oxford) 2010; 2010: baq018. Published online 2010 Jul 29. doi: 10.1093/database/baq018

PMCID:: PMC2945921

Article PDF–101K

Select item 40369118.

Adaptive Evolution of MRG, a Neuron-Specific Gene Family Implicated in Nociception

Sun Shim Choi, Bruce T. Lahn

Genome Res. 2003 Oct; 13(10): 2252–2259. doi: 10.1101/gr.1431603

PMCID:: PMC403691

Article PDF–353K

Select item 3470819.

Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R

Andreas W. Sailer, Hideki Sano, Zhizhen Zeng, Terrence P. McDonald, Jie Pan, Sheng-Shung Pong, Scott D. Feighner, Carina P. Tan, Takehiro Fukami, Hisashi Iwaasa, Donna L. Hreniuk, Nancy R. Morin, Sharon J. Sadowski, Makoto Ito, Masahiko Ito, Alka Bansal, Betty Ky, David J. Figueroa, Qingping Jiang, Christopher P. Austin, Douglas J. MacNeil, Akane Ishihara, Masaki Ihara, Akio Kanatani, Lex H. T. Van der Ploeg, Andrew D. Howard, Qingyun Liu

Proc Natl Acad Sci U S A. 2001 Jun 19; 98(13): 7564–7569. Published online 2001 Jun 12. doi: 10.1073/pnas.121170598

PMCID:: PMC34708

Article PDF–680K

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