PMC Links for Protein (Select 968121888) - PMC

Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 61110172.

DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling

Nanda Kumar Sasi, Flavie Coquel, Yea-Lih Lin, Jeffrey P MacKeigan, Philippe Pasero, Michael Weinreich

Neoplasia. 2018 Oct; 20(10): 985–995. Published online 2018 Aug 26. doi: 10.1016/j.neo.2018.08.001

PMCID:: PMC6111017

Abstract Article PDF–1004K

Select item 60650153.

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

Subhalakshmi Sharma, Kateřina Čermáková, Jan De Rijck, Jonas Demeulemeester, Milan Fábry, Sara El Ashkar, Siska Van Belle, Martin Lepšík, Petr Tesina, Vojtěch Duchoslav, Petr Novák, Martin Hubálek, Pavel Srb, Frauke Christ, Pavlína Řezáčová, H. Courtney Hodges, Zeger Debyser, Václav Veverka

Proc Natl Acad Sci U S A. 2018 Jul 24; 115(30): E7053–E7062. Published online 2018 Jul 11. doi: 10.1073/pnas.1803909115

PMCID:: PMC6065015

Abstract Article PDF–1.8M

Select item 57170014.

Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer

An Ning Cheng, Chi-Chen Fan, Yu-Kang Lo, Cheng-Liang Kuo, Hui-Chun Wang, I.-Hsin Lien, Shu-Yu Lin, Chung-Hsing Chen, Shih Sheng Jiang, I.-Shou Chang, Hsueh-Fen Juan, Ping-Chiang Lyu, Alan Yueh-Luen Lee

Sci Rep. 2017; 7: 17024. Published online 2017 Dec 5. doi: 10.1038/s41598-017-17126-2

PMCID:: PMC5717001

Abstract Article PDF–3.9M

Select item 55316115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 11716376.

Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication.

W Jiang, D McDonald, T J Hope, T Hunter

EMBO J. 1999 Oct 15; 18(20): 5703–5713. doi: 10.1093/emboj/18.20.5703

PMCID:: PMC1171637

Summary PDF–390K

Select item 843517.

A Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G₁/S Transition in Mammalian Cells

Hiroyuki Kumagai, Noriko Sato, Masayuki Yamada, Daniel Mahony, Wolfgang Seghezzi, Emma Lees, Ken-Ichi Arai, Hisao Masai

Mol Cell Biol. 1999 Jul; 19(7): 5083–5095. doi: 10.1128/mcb.19.7.5083

PMCID:: PMC84351

Abstract Article PDF–2.7M

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