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Full record GDS4334

B7x effect on CD8 T cell-mediated diabetes model AI4αβ: pancreatic CD8 T cells

Analysis of pancreatic AI4αβ CD8 T cells isolated from Rip-B7xAI4αβ (overexpressing B7x in the β cells) and AI4αβ (lacking B7x) mice. B7x inhibits CD8 T cell-induced diabetes. Results provide insight into the molecular basis for abrogation of diabetes by B7x overexpression in β cells.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 disease state, 2 genotype/variation sets
Platform:
GPL6246
Series:
GSE40225
6 Samples
Download data: CEL

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