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Scamp2 secretory carrier membrane protein 2 [ Mus musculus (house mouse) ]

Gene ID: 24044, updated on 9-Dec-2024

Summary

Official Symbol
Scamp2provided by MGI
Official Full Name
secretory carrier membrane protein 2provided by MGI
Primary source
MGI:MGI:1346518
See related
Ensembl:ENSMUSG00000040188 AllianceGenome:MGI:1346518
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sc2
Summary
Predicted to be involved in protein transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in recycling endosome membrane and trans-Golgi network membrane. Orthologous to human SCAMP2 (secretory carrier membrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in large intestine adult (RPKM 92.7), testis adult (RPKM 90.3) and 28 other tissues See more
Orthologs
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Genomic context

See Scamp2 in Genome Data Viewer
Location:
9 B; 9 31.05 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (57468227..57496081)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (57560944..57588798)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11408 Neighboring gene cytochrome c oxidase subunit 5A Neighboring gene family with sequence similarity 219, member B Neighboring gene mannose phosphate isomerase Neighboring gene STARR-positive B cell enhancer ABC_E3834 Neighboring gene STARR-positive B cell enhancer ABC_E3835 Neighboring gene unc-51-like kinase 3 Neighboring gene complexin 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

General gene information

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in protein transport  
involved_in protein transport  
involved_in protein transport  
Component Evidence Code Pubs
located_in Golgi apparatus  
located_in intracellular membrane-bounded organelle  
located_in membrane  
located_in membrane  
is_active_in recycling endosome membrane  
located_in recycling endosome membrane  
located_in recycling endosome membrane  
is_active_in trans-Golgi network membrane  
located_in trans-Golgi network membrane  
located_in trans-Golgi network membrane  

General protein information

Preferred Names
secretory carrier-associated membrane protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001378928.1NP_001365857.1  secretory carrier-associated membrane protein 2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC122528, AC164548
    UniProtKB/TrEMBL
    Q3TU28
    Conserved Domains (1) summary
    pfam04144
    Location:161336
    SCAMP; SCAMP family
  2. NM_022813.3NP_073724.1  secretory carrier-associated membrane protein 2 isoform 2

    See identical proteins and their annotated locations for NP_073724.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AF295402, AK161002, CA979044, CX217627
    Consensus CDS
    CCDS23224.1
    UniProtKB/Swiss-Prot
    Q9ERN0
    UniProtKB/TrEMBL
    Q3TAL2, Q3TU28
    Related
    ENSMUSP00000038350.10, ENSMUST00000045791.11
    Conserved Domains (1) summary
    pfam04144
    Location:118293
    SCAMP; SCAMP family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    57468227..57496081
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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