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    spds-1 PABS domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174914, updated on 9-Dec-2024

    Summary

    Official Symbol
    spds-1
    Official Full Name
    PABS domain-containing protein
    Primary source
    WormBase:WBGene00012909
    Locus tag
    CELE_Y46G5A.19
    See related
    AllianceGenome:WB:WBGene00012909
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable spermidine synthase activity. Predicted to be involved in spermidine biosynthetic process. Predicted to be active in cytosol. Orthologous to human SRM (spermidine synthase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See spds-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (12806899..12810872)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene R3H-associated N-terminal domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Nuclear receptor domain-containing protein Neighboring gene Phospholipid/glycerol acyltransferase domain-containing protein Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables catalytic activity  
    enables spermidine synthase activity  
    enables spermidine synthase activity  
    enables transferase activity  
    Process Evidence Code Pubs
    involved_in polyamine biosynthetic process  
    involved_in polyamine metabolic process  
    involved_in spermidine biosynthetic process  
    Component Evidence Code Pubs
    is_active_in cytosol  

    General protein information

    Preferred Names
    PABS domain-containing protein
    NP_001366953.1
    • Confirmed by transcript evidence
    NP_001367196.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12806899..12810872
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381635.2NP_001366953.1  PABS domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFG3
      Conserved Domains (1) summary
      cl17173
      Location:7314
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    2. NM_001381634.1NP_001367196.1  PABS domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B4E3X6
      Conserved Domains (1) summary
      cl17173
      Location:7366
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
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