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arx-4 putative actin-related protein 2/3 complex subunit 2 [ Caenorhabditis elegans ]

Gene ID: 175247, updated on 9-Dec-2024

Summary

Official Symbol
arx-4
Official Full Name
putative actin-related protein 2/3 complex subunit 2
Primary source
WormBase:WBGene00021170
Locus tag
CELE_Y6D11A.2
See related
AllianceGenome:WB:WBGene00021170
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable actin filament binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in epithelial cell migration and morphogenesis of embryonic epithelium. Predicted to be located in actin cytoskeleton and cytoplasm. Predicted to be part of Arp2/3 protein complex. Is expressed in head; intestine; pharynx; and tail. Orthologous to human ARPC2 (actin related protein 2/3 complex subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See arx-4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (862306..865398)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Putative ATP-dependent DNA helicase Q1 Neighboring gene Exoribonuclease phosphorolytic domain-containing protein Neighboring gene ZSWIM3 N-terminal domain-containing protein Neighboring gene Protein DPCD

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables actin binding  
enables actin filament binding  
enables structural constituent of cytoskeleton  
Component Evidence Code Pubs
part_of Arp2/3 protein complex  
part_of Arp2/3 protein complex  
located_in actin cytoskeleton  
located_in cytoplasm  
located_in cytoskeleton  

General protein information

Preferred Names
putative actin-related protein 2/3 complex subunit 2
NP_001370783.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    862306..865398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001384017.1NP_001370783.1  putative actin-related protein 2/3 complex subunit 2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8WTM6
    Conserved Domains (1) summary
    pfam04045
    Location:57286
    P34-Arc; Arp2/3 complex, 34 kD subunit p34-Arc
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