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Full record GDS5012

ash-2 knockdown effect on germline-deficient glp-1(e2141ts) mutant: day 8 (mid-life stage)

Analysis of day 8 germline-deficient glp-1 mutants treated with ash-2 RNAi. The ASH-2 trithorax complex trimethylates histone H3 at lysine 4 (H3K4); an intact germline is required for ASH-2-induced lifespan extension. Results provide insight into the role of histone methylation in longevity.
Organism:
Caenorhabditis elegans
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets
Platform:
GPL200
Series:
GSE30505
11 Samples
Download data: CEL

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