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klp-15 Kinesin motor domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172213, updated on 9-Dec-2024

Summary

Official Symbol
klp-15
Official Full Name
Kinesin motor domain-containing protein
Primary source
WormBase:WBGene00002225
Locus tag
CELE_M01E11.6
See related
AllianceGenome:WB:WBGene00002225
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables minus-end-directed microtubule motor activity. Involved in chromosome segregation and microtubule-based movement. Predicted to be located in cytoskeleton. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in germ line and hypodermis. Orthologous to human KIFC1 (kinesin family member C1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See klp-15 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (5577070..5579194, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene CSD domain-containing protein Neighboring gene RecQ-mediated genome instability protein 1 homolog Neighboring gene Beta-catenin-like protein 1 N-terminal domain-containing protein Neighboring gene Protein-S-isoprenylcysteine O-methyltransferase Neighboring gene Tensin homolog

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding  
enables ATP hydrolysis activity  
enables cytoskeletal motor activity  
enables microtubule binding  
enables microtubule binding  
enables microtubule motor activity  
enables microtubule motor activity  
enables minus-end-directed microtubule motor activity PubMed 
Process Evidence Code Pubs
involved_in chromosome segregation PubMed 
involved_in microtubule-based movement  
involved_in microtubule-based movement PubMed 
involved_in microtubule-based movement  
involved_in mitotic spindle assembly  
Component Evidence Code Pubs
is_active_in cytoplasm  
located_in cytoplasm  
located_in cytoskeleton  
part_of kinesin complex  
is_active_in microtubule  
is_active_in microtubule organizing center  
is_active_in mitotic spindle  
is_active_in nucleus  

General protein information

Preferred Names
Kinesin motor domain-containing protein
NP_491633.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5577070..5579194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059232.5NP_491633.1  Kinesin motor domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491633.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91400, Q9NL41
    Conserved Domains (4) summary
    PHA03378
    Location:27153
    PHA03378; EBNA-3B; Provisional
    cd00106
    Location:248564
    KISc; Kinesin motor domain
    pfam12718
    Location:147242
    Tropomyosin_1; Tropomyosin like
    pfam16326
    Location:147193
    ABC_tran_CTD; ABC transporter C-terminal domain
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