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    CG13392 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34157, updated on 4-Jan-2025

    Summary

    Official Symbol
    CG13392provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032033
    Locus tag
    Dmel_CG13392
    See related
    AllianceGenome:FB:FBgn0032033
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    2L11; Dmel\CG13392; dTMEM126B
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex I assembly. Is active in mitochondrion. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 29 and optic atrophy 7. Orthologous to human TMEM126A (transmembrane protein 126A) and TMEM126B (transmembrane protein 126B). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See CG13392 in Genome Data Viewer
    Location:
    29B3-29B4; 2-31 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8381821..8382807, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8381821..8382807, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Alanyl-tRNA synthetase Neighboring gene Reduction in Cnn dots 4 Neighboring gene Defender against apoptotic cell death 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in mitochondrion  
    is_active_in mitochondrion PubMed 

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG13392-PA
    CG13392-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8381821..8382807 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273318.1NP_001260247.1  uncharacterized protein Dmel_CG13392, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260247.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLM7
      Conserved Domains (1) summary
      pfam07114
      Location:39207
      DUF1370; Protein of unknown function (DUF1370)
    2. NM_135376.2NP_609220.1  uncharacterized protein Dmel_CG13392, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609220.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLM7
      Related
      FBpp0079325
      Conserved Domains (1) summary
      pfam07114
      Location:39207
      DUF1370; Protein of unknown function (DUF1370)
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