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Akap17b A kinase anchor protein 17B [ Mus musculus (house mouse) ]

Gene ID: 338351, updated on 4-Jan-2025

Summary

Official Symbol
Akap17bprovided by MGI
Official Full Name
A kinase anchor protein 17Bprovided by MGI
Primary source
MGI:MGI:2443758
See related
Ensembl:ENSMUSG00000059708 AllianceGenome:MGI:2443758
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Talia; PRKA17B; Sfrs17b; Srsf17b; AKAP-17B; B230333C21Rik; C230056F04Rik
Summary
Predicted to enable protein kinase A binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in cytosol and nuclear speck. Predicted to be part of spliceosomal complex. Is expressed in several structures, including extraembryonic component; heart; liver; lung; and spleen. Orthologous to several human genes including AKAP17A (A-kinase anchoring protein 17A). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in CNS E18 (RPKM 2.2), frontal lobe adult (RPKM 1.8) and 21 other tissues See more
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Genomic context

See Akap17b in Genome Data Viewer
Location:
X A3.3; X 21.01 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (35871832..35909021, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (36608173..36645465, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene 14569 Neighboring gene progesterone receptor membrane component 1 Neighboring gene STARR-seq mESC enhancer starr_46998 Neighboring gene ribosomal protein L7, pseudogene 9 Neighboring gene predicted gene, 57674

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding  
enables molecular_function  
enables protein kinase A binding  
Process Evidence Code Pubs
involved_in RNA splicing  
involved_in biological_process  
involved_in mRNA processing  
Component Evidence Code Pubs
located_in cytosol  
located_in nuclear speck  
located_in nuclear speck  
located_in nucleus  
part_of spliceosomal complex  

General protein information

Preferred Names
A-kinase anchor protein 17B
Names
A kinase (PRKA) anchor protein 17B
protein Talia
protein kinase A-anchoring protein 17B
serine/arginine-rich splicing factor 17B
splicing factor, arginine/serine-rich 17b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081956.2NP_001075425.1  A-kinase anchor protein 17B isoform 1

    See identical proteins and their annotated locations for NP_001075425.1

    Status: VALIDATED

    Source sequence(s)
    AL450397
    Consensus CDS
    CCDS40924.1
    UniProtKB/Swiss-Prot
    A2A3V1, B0QZD2, Q0P534, Q8BR01, Q8C6P6
    Related
    ENSMUSP00000052042.7, ENSMUST00000051906.13
    Conserved Domains (1) summary
    cd12264
    Location:143262
    RRM_AKAP17A; RNA recognition motif found in A-kinase anchor protein 17A (AKAP-17A) and similar proteins
  2. NM_001419768.1NP_001406697.1  A-kinase anchor protein 17B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL450397
    UniProtKB/Swiss-Prot
    A2A3V1, B0QZD2, Q0P534, Q8BR01, Q8C6P6
  3. NM_001419769.1NP_001406698.1  A-kinase anchor protein 17B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL450397

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    35871832..35909021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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