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Chain A, TOXIN FS2

PDB: 1TFS_A

Identical Proteins FASTA Graphics 

LOCUS       1TFS_A                    60 aa            linear   VRT 23-OCT-2024
DEFINITION  Chain A, TOXIN FS2.
ACCESSION   1TFS_A
VERSION     1TFS_A
DBSOURCE    pdb: molecule 1TFS, chain A, release Oct 23, 2024;
            deposition: Jan 26, 1995;
            class: TOXIN;
            source: Mmdb_id: 57453, Pdb_id 1: 1TFS;
            Exp. method: Solution NMR.
KEYWORDS    .
SOURCE      Dendraspis polylepis polylepis (black mamba)
  ORGANISM  Dendraspis polylepis polylepis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata;
            Toxicofera; Serpentes; Colubroidea; Elapidae; Elapinae;
            Dendroaspis.
REFERENCE   1  (residues 1 to 60)
  AUTHORS   Albrand,J.P., Blackledge,M.J., Pascaud,F., Hollecker,M. and
            Marion,D.
  TITLE     NMR and restrained molecular dynamics study of the
            three-dimensional solution structure of toxin FS2, a specific
            blocker of the L-type calcium channel, isolated from black mamba
            venom
  JOURNAL   Biochemistry 34 (17), 5923-5937 (1995)
   PUBMED   7727450
REFERENCE   2  (residues 1 to 60)
  AUTHORS   Albrand,J.-P., Blackledge,M.J., Pascaud,F., Hollecker,M. and
            Marion,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-1995)
COMMENT     On Nov 7, 2007 this sequence version replaced gi:157833934.
            NMR AND RESTRAINED MOLECULAR DYNAMICS STUDY OF THE
            THREE-DIMENSIONAL SOLUTION STRUCTURE OF TOXIN FS2, A SPECIFIC
            BLOCKER OF THE L-TYPE CALCIUM CHANNEL, ISOLATED FROM BLACK MAMBA
            VENOM.
FEATURES             Location/Qualifiers
     source          1..60
                     /organism="Dendraspis polylepis polylepis"
                     /db_xref="taxon:8620"
     Region          1..59
                     /region_name="TFP_snake_toxin"
                     /note="Snake toxin domain; cd00206"
                     /db_xref="CDD:467061"
     SecStr          1..6
                     /sec_str_type="sheet"
                     /note="strand 1"
     Bond            bond(3,22)
                     /bond_type="disulfide"
     SecStr          12..17
                     /sec_str_type="sheet"
                     /note="strand 2"
     Bond            bond(17,39)
                     /bond_type="disulfide"
     SecStr          21..27
                     /sec_str_type="sheet"
                     /note="strand 3"
     SecStr          35..40
                     /sec_str_type="sheet"
                     /note="strand 4"
     Bond            bond(41,52)
                     /bond_type="disulfide"
     SecStr          48..54
                     /sec_str_type="sheet"
                     /note="strand 5"
     Bond            bond(53,58)
                     /bond_type="disulfide"
ORIGIN      
        1 ricyshkasl pratktcven tcykmfirth reyisergcg cptamwpyqt ecckgdrcnk
//
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