RecName: Full=Serine protease HTRA1; AltName: Full=High-temperature re - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

TGF-β/Smad Signalling Activation by HTRA1 Regulates the Function of Human Lens Epithelial Cells and Its Mechanism in Posterior Subcapsular Congenital Cataract. [Int J Mol Sci. 2022]
TGF-β/Smad Signalling Activation by HTRA1 Regulates the Function of Human Lens Epithelial Cells and Its Mechanism in Posterior Subcapsular Congenital Cataract.
Lin X, Yang T, Liu X, Fan F, Zhou X, Li H, Luo Y. Int J Mol Sci. 2022 Nov 20; 23(22). Epub 2022 Nov 20.
Endoplasmic reticulum stress-regulated high temperature requirement A1 (HTRA1) modulates invasion and angiogenesis-related genes in human trophoblasts. [J Pharmacol Sci. 2022]
Endoplasmic reticulum stress-regulated high temperature requirement A1 (HTRA1) modulates invasion and angiogenesis-related genes in human trophoblasts.
Yoshida K, Kusama K, Azumi M, Yoshie M, Kato K, Tamura K. J Pharmacol Sci. 2022 Dec; 150(4):267-274. Epub 2022 Oct 7.
Clinical features and pathogenicity assessment in patients with HTRA1-autosomal dominant disease. [Neurol Sci. 2023]
Clinical features and pathogenicity assessment in patients with HTRA1-autosomal dominant disease.
He Z, Wang L, Zhang Y, Yin C, Niu Y. Neurol Sci. 2023 Feb; 44(2):639-647. Epub 2022 Oct 18.

RefSeq genomic sequence
See the genomic reference sequence for the HTRA1 gene (NG_011554.1).
RefSeq protein
See the reference protein sequence for serine protease HTRA1 precursor (NP_002766.1).

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Q92743 [Domain Mapping of Disease Mut...]
Q92743
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Serine protease HTRA1; AltName: Full=High-temperature requirement ...
RecName: Full=Serine protease HTRA1; AltName: Full=High-temperature requirement A serine peptidase 1; AltName: Full=L56; AltName: Full=Serine protease 11; Flags: Precursor
gi|18202620|sp|Q92743.1|HTRA1_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein