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G-protein coupled receptor GRL101 isoform X1 [Octopus sinensis]

NCBI Reference Sequence: XP_036356975.1

Identical Proteins FASTA Graphics 

LOCUS       XP_036356975            1123 aa            linear   INV 08-OCT-2020
DEFINITION  G-protein coupled receptor GRL101 isoform X1 [Octopus sinensis].
ACCESSION   XP_036356975
VERSION     XP_036356975.1
DBLINK      BioProject: PRJNA551489
DBSOURCE    REFSEQ: accession XM_036501082.1
KEYWORDS    RefSeq.
SOURCE      Octopus sinensis (East Asian common octopus)
  ORGANISM  Octopus sinensis
            Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca;
            Cephalopoda; Coleoidea; Octopodiformes; Octopoda; Incirrata;
            Octopodidae; Octopus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_042999.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Octopus sinensis Annotation Release
                                           101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1123
                     /organism="Octopus sinensis"
                     /db_xref="taxon:2607531"
                     /linkage_group="LG3"
     Protein         1..1123
                     /product="G-protein coupled receptor GRL101 isoform X1"
                     /calculated_mol_wt=127624
     Region          67..101
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(72,80,91..92)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(84,87,91,97..98)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            94..98
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          106..140
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(111,119,130..131)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(123,126,130,136..137)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            133..137
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          145..179
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(150,158,169..170)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(162,165,169,175..176)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            172..176
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          180..213
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(183,191,202..203)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(195,198,202,209..210)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            206..210
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          215..242
                     /region_name="LDLa"
                     /note="Low-density lipoprotein receptor domain class A;
                     smart00192"
                     /db_xref="CDD:197566"
     Site            order(221,229,240..241)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(233,236,240,247..248)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            order(243,245..248)
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          256..295
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(262,271,282..283)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(275,278,282,291..292)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            order(285,289..292)
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          309..338
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(309,317,328..329)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(321,324,328,334..335)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            331..335
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          343..377
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(348,356,367..368)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(360,363,367,373..374)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            370..374
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          382..416
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(387,395,406..407)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(399,402,406,412..413)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            409..413
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          465..500
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(470,478,489..490)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(482,485,489,496..497)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            493..497
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          536..558
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          <545..>707
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          559..582
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          583..606
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          607..630
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          631..654
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          655..678
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          679..702
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          741..1023
                     /region_name="7tmA_Relaxin_R"
                     /note="relaxin family peptide receptors, member of the
                     class A family of seven-transmembrane G protein-coupled
                     receptors; cd15137"
                     /db_xref="CDD:320265"
     Region          741..767
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320265"
     Region          774..799
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320265"
     Site            order(795,798..799,819..824,826..827,830,874,876..880,909,
                     912..914,916..918,920..921,972,975..976,978..979,982,
                     990..991,993..995,998,1001..1002)
                     /site_type="other"
                     /note="putative peptide ligand binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:320265"
     Region          819..849
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320265"
     Region          860..882
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320265"
     Region          909..938
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320265"
     Region          952..982
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320265"
     Region          991..1016
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320265"
     CDS             1..1123
                     /gene="LOC115209347"
                     /coded_by="XM_036501082.1:854..4225"
                     /db_xref="GeneID:115209347"
ORIGIN      
        1 meshllvfiv lisatatiya sflipcqten aftcdeaske cisaeqkcng isecsngfde
       61 svktcgclph efqcnetncv dlvkrcdtvq dcdagedein cesyvcpvhr tkcknylcvp
      121 stamcnfidd cgdnsdeenc kyrscylaef rcnnsecipe sllcdgiqdc vdgsdetece
      181 shfqcsngly ihkdkvcdfh rdclidhdde tncgkcperk yqcqsgecid isnqcdgicd
      241 cahtcddenk cgsmwcqage qfmcpknyrc ikkeflcdgf ndckntwrgt desfcvnssn
      301 scnifksnfm cqegrclpsl lqcntfidcl ngedesnctl qlctknefrc sdnrcidkky
      361 rcdgkgncyd rsdehgcety dcppghrkcr ggqciaenkw cdfwrdcpdn sdeedcelrp
      421 ckrdefkcdn gqcipgylrc fkgpntdrlg cadyshlkqc qntkcesdqf kcrnaycitq
      481 kqvcngktdc lmskwdefhc aykcpyptde cvcfdismnc tnrglfhvpn nnegsiqfhl
      541 agnflnytls adtfkiydlt tldisnnsls tippdcfagl wrlqslnlad nqlteiendt
      601 fvglsglrsl niernniqti lpnafrglss lstldlskqr ltfieknvfn glrklrflnl
      661 sgnqitnied gafnglknll tldisnnmli tigenvfhgl tnlhtlytde yrfcclakgv
      721 pdcnpkpdef sscedlmsny vlrasiwilg itasfgnviv iiwrtrdkrs gkvhsflitn
      781 lalgdmfmgv ylmiiavadt yyrgsyilyd klwrssilch fagfiatfss elsvftltvi
      841 tldrlicilf pfrshrmglk eaqlamlalw ifvfflsavp lfgieyfkdf ysrsgvclal
      901 hitpdrprgw eysvmiflav nllsfliifi sylwmfivak ktrsavrtae tktdsamakr
      961 itlivltdff cwipiiilgi aslcgqripp evyawvavfi lpvnsainpv lytlstapfl
     1021 gnvrkratkf rksfmtsltf dtkhsyvedr tsgnywertn snyrqfeimr mrpmtkcsss
     1081 qtpanngikv eeyipkdmkl eklkseqdsa hsqvevtqte dfv
//
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the LOC115209347 gene (XM_036501082.1).
  • RefSeq protein isoforms
    See the other reference sequence protein isoform for the LOC115209347 gene (XP_029633576.2).

More about the gene LOC115209347

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