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regulating synaptic membrane exocytosis protein 2 isoform X11 [Rattus norvegicus]

NCBI Reference Sequence: XP_038934208.1

Identical Proteins FASTA Graphics 

LOCUS       XP_038934208            1643 aa            linear   ROD 22-FEB-2024
DEFINITION  regulating synaptic membrane exocytosis protein 2 isoform X11
            [Rattus norvegicus].
ACCESSION   XP_038934208
VERSION     XP_038934208.1
DBLINK      BioProject: PRJNA1074393
DBSOURCE    REFSEQ: accession XM_039078280.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086025) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Rattus norvegicus"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     Protein         1..1643
                     /product="regulating synaptic membrane exocytosis protein
                     2 isoform X11"
                     /calculated_mol_wt=185590
     Region          174..206
                     /region_name="BRcat_Rcat_RBR"
                     /note="BRcat (benign-catalytic) and Rcat
                     (required-for-catalysis) domains, part of the RBR
                     (RING1-BRcat-Rcat) domain; cl45895"
                     /db_xref="CDD:459240"
     Site            order(176,192,195,200,203)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:438995"
     Region          <192..240
                     /region_name="FYVE_like_SF"
                     /note="FYVE domain like superfamily; cl28890"
                     /db_xref="CDD:333710"
     Region          711..810
                     /region_name="PDZ_RIM-like"
                     /note="PDZ domain of Rab3-interacting molecule 1 (RIM),
                     RIM2, piccolo and related domains; cd06714"
                     /db_xref="CDD:467198"
     Site            order(735..741,756,759,789,793,796..797)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467198"
     Region          881..1004
                     /region_name="C2A_RIM1alpha"
                     /note="C2 domain first repeat contained in
                     Rab3-interacting molecule (RIM) proteins; cd04031"
                     /db_xref="CDD:175997"
     Site            order(909,915,970,972,980)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:175997"
     Region          1474..1619
                     /region_name="C2B_RIM1alpha"
                     /note="C2 domain second repeat contained in
                     Rab3-interacting molecule (RIM) proteins; cd04028"
                     /db_xref="CDD:175994"
     Site            order(1531,1535..1536,1538,1541,1569,1571,1573,1617..1618)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:175994"
     CDS             1..1643
                     /gene="Rims2"
                     /gene_synonym="Nim2; Rim2"
                     /coded_by="XM_039078280.2:259..5190"
                     /db_xref="GeneID:116839"
                     /db_xref="RGD:620001"
ORIGIN      
        1 mylsqprrlp qppapqpplp velppcfprv vrlhqtcrlh sgpgaarlpp rrplsllrsp
       61 rcrtsatsrk rrgkssrlsw ivrrkkrrrs spcsrskkst nhnrhitlfa ylnrwfpfsg
      121 itelvnnvlq pqqkqhneke pptklhqqfe mykeqvkkmg eesqqqqeqk gdaptcgich
      181 ktkfadgcgh ncsycqtkfc arcggrvslr snkedkvvmw vcnlcrkqqe iltksgawfy
      241 nsgsntpqqp dqkalrglrs eeapqekkak lheqtqfqgp pgdssvpave rgrahgltrq
      301 dsikngsgmk hqiasdmpsd rkrspsvsrd qnrrydqsee reeysqyvps dstmprspsd
      361 yadrrsqrep qfyeepdhln yrdsnrrghr hskeyivdde dvesrdeyer qrreeeyqar
      421 yrsdpnlary pvkpqpyeeq mrihaevsra rherrhsdvs lanaeledsr isllrmdrps
      481 rqrsvserra amenqrsysm ertreaqgqs sypqrttnhs pptprrspip ldrpelrrad
      541 slrkqhhldp ssavrktkre kmetmlrnds lssdqsesvr pppprphksk kggkmrqvsl
      601 ssseeelast peytscddve iesesvsekg dsqkgkrkts eqavwsdsnt rserqkkvmy
      661 sgghsldedl ewsepqtkds gvdtcssttl neershsdeh pvtwqpskdg drligrilln
      721 krlkdgsvpr dsgamlglkv vggkmtesgr lcafitkvkk gsladtvghl rpgdevlewn
      781 grllqgatfe evyniilesk pepqvelvvs rpigdmprip dsthaqless sssfesqkmd
      841 rpsisvtspm spgmlrdvpq flsgqlssqs lsrrttpfvp rvqiklwfdk vghqlivtil
      901 gakdlpsred grprnpyvki yflpdrsdkn krrtktvkkt lepkwnqtfi yspvhrrefr
      961 ermleitlwd qarvreeese flgeiliele tallddephw yklqthdvss lplphpspym
     1021 prrqlhgesp trrlqnkalc scssgskris dsevsdydce dgvgvvsdyr hdgrdlqsst
     1081 lsvpeqvmss nhcspsgsph rvdvigrtrs wspsvpppqr nveqglrgtr atghyntisr
     1141 mdrhrvmddh ysserdrshp rtgsvqtsps stpvtgrrgr qlpqlppkgt lermitedmd
     1201 strkrnsgam dieernrqmk lnkykqvags dprleqdyhs kyrsgwdphr gadtvstkss
     1261 dsdvsdvsav srtssasrfs stsymsvqse rprgnrkisf splvqecgaq apvqpplipl
     1321 gpdinvftsk mqsrqmgvsg ksmakstsis gdmcsleknd gsqsdtavga lgtsgkkrrs
     1381 sigakmvaiv glsrksrsas qlsqtegggk klrstvqrst etglavemrn wmtrqasres
     1441 tdgsmnsyss egnlifpgvr lasdsqfsdf ldglgpaqlv grqtlatpam gdiqvgmmdk
     1501 kgqleveiir arglvvkpgs ktlpapyvkv ylldngvcia kkktkvarkt leplyqqlls
     1561 feespqgkvl qiivwgdygr mdhksfmgva qilldelels nmvigwfklf ppsslvdptl
     1621 apltrrasqs slesstgpsy srs
//
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