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lymphocyte associated receptor of death 1a [Homo sapiens]

GenBank: AAC51306.1

Identical Proteins FASTA Graphics 

LOCUS       AAC51306                 417 aa            linear   PRI 14-MAY-1997
DEFINITION  lymphocyte associated receptor of death 1a [Homo sapiens].
ACCESSION   AAC51306
VERSION     AAC51306.1
DBSOURCE    locus HSU94501 accession U94501.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 417)
  AUTHORS   Screaton,G.R., Xu,X.N., Olsen,A.L., Cowper,A.E., Tan,R.,
            McMichael,A.J. and Bell,J.I.
  TITLE     LARD: a new lymphoid-specific death domain containing receptor
            regulated by alternative pre-mRNA splicing
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 94 (9), 4615-4619 (1997)
   PUBMED   9114039
REFERENCE   2  (residues 1 to 417)
  AUTHORS   Screaton,G.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-MAR-1997) Molecular Immunology Group, Institute of
            Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3
            9DU, UK
COMMENT     Method: conceptual translation supplied by author.
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /cell_line="HeLa"
                     /cell_type="lymphocyte"
     Protein         1..417
                     /product="lymphocyte associated receptor of death 1a"
                     /function="mediates apoptosis"
                     /name="LARD-1a; membrane protein"
     Region          32..145
                     /region_name="TNFRSF25"
                     /note="tumor necrosis factor receptor superfamily member
                     25 (TNFRSF25), also known as death receptor 3 (DR3);
                     cd13420"
                     /db_xref="CDD:276925"
     Region          35..70
                     /region_name="CRD1"
                     /note="CRD1 [structural motif]"
                     /db_xref="CDD:276925"
     Region          73..115
                     /region_name="CRD2"
                     /note="CRD2 [structural motif]"
                     /db_xref="CDD:276925"
     Region          117..141
                     /region_name="CRD3"
                     /note="CRD3 [structural motif]"
                     /db_xref="CDD:276925"
     Region          334..410
                     /region_name="Death_TNFRSF25_DR3"
                     /note="Death domain of Tumor Necrosis Factor Receptor
                     superfamily 25; cd08815"
                     /db_xref="CDD:176793"
     CDS             1..417
                     /coded_by="U94501.1:1..1254"
                     /note="similar to Fas and TNF-R1; contains a death domain"
ORIGIN      
        1 meqrprgcaa vaaalllvll garaqggtrs prcdcagdfh kkiglfccrg cpaghylkap
       61 ctepcgnstc lvcpqdtfla wenhhnseca rcqacdeqas qvalencsav adtrcgckpg
      121 wfvecqvsqc vssspfycqp cldcgalhrh trllcsrrdt dcgtclpgfy ehgdgcvscp
      181 tstlgscper caavcgwrqm fwvqvllagl vvplllgatl tytyrhcwph kplvtadeag
      241 mealtpppat hlspldsaht llappdssek ictvqlvgns wtpgypetqe alcpqvtwsw
      301 dqlpsralgp aaaptlspes pagspammlq pgpqlydvmd avparrwkef vrtlglreae
      361 ieaveveigr frdqqyemlk rwrqqqpagl gavyaalerm gldgcvedlr srlqrgp
//
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